Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Beta-secretase 1 (389/390 > 99%)† (Homo sapiens (Human)) | BDBM202615![]() (US9242943, 24) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar | PC cid PC sid PDB UniChem | US Patent | n/a | n/a | 250 | n/a | n/a | n/a | n/a | n/a | n/a |
Siena Biotech SpA US Patent | Assay Description DNA of the human APP wt gene (APP695) were used to assess the potency of the compounds in a cellular assay. The cells were seeded in 96-well microtit... | US Patent US9242943 (2016) BindingDB Entry DOI: 10.7270/Q2833QV5 | |||||||||||
More data for this Ligand-Target Pair |