Affinity Data by PDB ID

PDB code 5F00

Found 1 hit Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Beta-secretase 1 (389/390 > 99%)^† (Homo sapiens (Human))	BDBM202615 (US9242943, 24) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar	PC cid PC sid PDB UniChem	US Patent	n/a	n/a	250	n/a	n/a	n/a	n/a	n/a	n/a
SIENA BIOTECH S.P.A.; HOFFMANN-LA ROCHE INC. US Patent					Assay Description DNA of the human APP wt gene (APP695) were used to assess the potency of the compounds in a cellular assay. The cells were seeded in 96-well microtit...				US Patent US9242943 (2016) BindingDB Entry DOI: 10.7270/Q2833QV5
SIENA BIOTECH S.P.A.; HOFFMANN-LA ROCHE INC. US Patent					More data for this Ligand-Target Pair

_* indicates data uncertainty>20%
* 0.9 Tanimoto similarity
† Identities from BLAST output