Affinity DataIC50: 1.37E+4nMpH: 7.5 T: 25°CAssay Description:Briefly, recombinant human or murine FD catalytic domain (10 nM concentration) were incubated with compound at various concentrations for 1 h at room...More data for this Ligand-Target Pair
3D Structure (crystal)Affinity DataIC50: 1.40E+4nMAssay Description:Binding affinity against alpha-2 adrenergic receptor from calf cerebral cortex, using [3H]prazosin as the radioligandMore data for this Ligand-Target Pair
Affinity DataIC50: 1.40E+4nMAssay Description:Inhibition of recombinant human complement factor D catalytic domain (G24 to A253 residues) expressed in Escherichia coli Rosetta using Z-Lys-thioben...More data for this Ligand-Target Pair
Affinity DataIC50: 1.40E+4nMAssay Description:Inhibition of human complement factor D using Z-L-Lys-SBzl hydrochloride as substrate preincubated for 15 mins followed by substrate addition and mea...More data for this Ligand-Target Pair
Affinity DataIC50: 1.40E+4nMAssay Description:Inhibition of recombinant complement factor D catalytic domain (unknown origin) using Z-Lys-thiobenzyl as substrate pretreated for 1 hr followed by s...More data for this Ligand-Target Pair
Affinity DataIC50: 1.40E+4nMAssay Description:Inhibition of recombinant human factor D expressed in Escherichia coli using Z-Lys-thiobenzyl as substrate after 1 hr by spectrofluorimetryMore data for this Ligand-Target Pair
Affinity DataIC50: >1.40E+4nMAssay Description:Inhibition of recombinant human CFD catalytic domain (G24 to A253 residues) expressed in Escherichia coli (Rosetta) using Z-Lys-thiobenzyl and 2,4-di...More data for this Ligand-Target Pair
Affinity DataIC50: 3.32E+4nMpH: 7.4 T: 4°CAssay Description:Recombinant human FD (10 nM concentration) was incubated with compound
at various concentrations for 1 h at room temperature in 0.1 M PBS (pH
7.4) ...More data for this Ligand-Target Pair
