Affinity Data by PDB ID

PDB code 5HE0

Found 1 hit Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Beta-adrenergic receptor kinase 1 (630/641 = 98%)^† (Homo sapiens (Human))	BDBM50173310 (CHEMBL3808660 \| US10023564, Example 1) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar	CHEMBL PC cid PC sid PDB UniChem Patents	PDB US Patent	n/a	n/a	150	n/a	n/a	n/a	n/a	7.0	n/a
The Regents of the University of Michigan US Patent					Assay Description GRK1, 2 and 5 kinetic assays were conducted in a buffer containing 20 mM HEPES pH 7.0, 5 μM ATP, 2 mM MgCl2, and 0.025% DDM with 50 nM GRK and e...				US Patent US10023564 (2018) BindingDB Entry DOI: 10.7270/Q2V126V5
The Regents of the University of Michigan US Patent					More data for this Ligand-Target Pair				3D Structure (crystal)

_* indicates data uncertainty>20%
* 0.9 Tanimoto similarity
† Identities from BLAST output