Affinity Data by PDB ID

PDB code 5IA5

Found 2 hits Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Ephrin type-A receptor 2 (EPHA2) (305/305 = 100%)^† (Homo sapiens (Human))	BDBM50100615 (E-7050 \| E7050 \| GOLVATINIB \| Golvatinib) Show SMILES Show InChI	PDB GoogleScholar	Purchase PC cid PC sid PDB UniChem Similars	PDB Article PubMed	n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
Technical University of Munich					Assay Description Refer to Reaction Biology Corps.				ACS Chem Biol 11: 3400-3411 (2016) Article DOI: 10.1021/acschembio.6b00709 BindingDB Entry DOI: 10.7270/Q2TD9W5M
Technical University of Munich					More data for this Ligand-Target Pair				3D Structure (crystal)
Ephrin type-A receptor 2 (EPHA2) (305/305 = 100%)^† (Homo sapiens (Human))	BDBM50100615 (E-7050 \| E7050 \| GOLVATINIB \| Golvatinib) Show SMILES Show InChI	PDB GoogleScholar	Purchase PC cid PC sid PDB UniChem Similars	PDB Article PubMed	n/a	n/a	n/a	25	n/a	n/a	n/a	n/a	n/a
Technical University of Munich					Assay Description Kinobeads competition assays were performed in 96-well format as previously described using mixed protein lysates of four cancer cell lines (K-562, M...				ACS Chem Biol 11: 3400-3411 (2016) Article DOI: 10.1021/acschembio.6b00709 BindingDB Entry DOI: 10.7270/Q2TD9W5M
Technical University of Munich					More data for this Ligand-Target Pair				3D Structure (crystal)

_* indicates data uncertainty>20%
* 0.9 Tanimoto similarity
† Identities from BLAST output