Compile Data Set for Download or QSAR
maximum 50k data
Found 3 Enz. Inhib. hit(s) for PDB: 5KU3
TargetBromodomain-containing protein 4(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM50200445(CHEMBL3897393 | US9763922, Example 300)
Affinity DataIC50:  5.49E+3nMAssay Description:His/Flag epitope tagged BRD4 BD142-168 was cloned, expressed, and purified to. BRD4 binding and inhibition was assessed by monitoring the engagement ...More data for this Ligand-Target Pair
TargetBromodomain-containing protein 4(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM340520(US9763922, Example 51)
Affinity DataIC50:  1.05E+4nMAssay Description:His/Flag epitope tagged BRD4 BD142-168 was cloned, expressed, and purified to. BRD4 binding and inhibition was assessed by monitoring the engagement ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetBromodomain-containing protein 4(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM50200445(CHEMBL3897393 | US9763922, Example 300)
Affinity DataIC50:  1.30E+4nMAssay Description:Displacement of biotinylated histone H3K14 peptide ligand from human recombinant His-tagged BRD4 bromodomain-1 measured after 10 mins by TR-FRET assa...More data for this Ligand-Target Pair