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Report error Found 3 Enz. Inhib. hit(s) for PDB: 5LMA
TargetTyrosine-protein kinase SYK(Human)
Glaxosmithkline R&D

Curated by ChEMBL
LigandPNGBDBM50535081(CHEMBL4436576)
Affinity DataIC50:  251nMAssay Description:Inhibition of N-terminal 6His-tagged full length human recombinant SYK expressed in baculovirus using Biotin-AAAEEIYGEI as substrate after 60 mins by...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetTyrosine-protein kinase SYK(Human)
Glaxosmithkline R&D

Curated by ChEMBL
LigandPNGBDBM50535081(CHEMBL4436576)
Affinity DataIC50:  1.26E+3nMAssay Description:Inhibition of SYK in human Ramos cells assessed as suppression of anti-IgM induced Erk1/2 phosphorylation preincubated for 30 mins followed by anti-I...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetTyrosine-protein kinase SYK(Human)
Glaxosmithkline R&D

Curated by ChEMBL
LigandPNGBDBM50535081(CHEMBL4436576)
Affinity DataIC50:  2.51E+3nMAssay Description:Inhibition of SYK in human B cells assessed as suppression of anti-IgM-induced CD69 surface expression preincubated for 30 mins followed by anti-IgM ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB