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Report error Found 5 Enz. Inhib. hit(s) for PDB: 5TIN
TargetGlycine receptor subunit alpha-3(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50229715(CHEMBL4070615)
Affinity DataEC50:  50nMAssay Description:Positive allosteric modulation of human glycine alpha3 receptor expressed in HEK293T cells assessed as potentiation of glycine-induced increase in ch...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedPDB3D3D Structure (crystal)

TargetGlycine receptor subunit alpha-3(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50229715(CHEMBL4070615)
Affinity DataKd:  11nMAssay Description:Binding affinity to human glycine alpha3 receptor expressed in HEK293T cells by SPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedPDB3D3D Structure (crystal)

TargetGlycine receptor subunit alpha-1/beta(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50229715(CHEMBL4070615)
Affinity DataEC50:  16nMAssay Description:Positive allosteric modulation of human glycine alpha1beta receptor expressed in HEK293T cells assessed as glycine-induced increase in current respon...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedPDB3D3D Structure (crystal)

TargetGlycine receptor subunit alpha-3(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50229715(CHEMBL4070615)
Affinity DataEC50:  50nMAssay Description:Positive allosteric modulation of human glycine alpha3 receptor expressed in HEK293T cells assessed as glycine-induced increase in current response a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedPDB3D3D Structure (crystal)

TargetGlycine receptor subunit alpha-1(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50229715(CHEMBL4070615)
Affinity DataEC50:  32nMAssay Description:Positive allosteric modulation of human glycine alpha1 receptor expressed in HEK293T cells assessed as glycine-induced increase incurrent response af...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedPDB3D3D Structure (crystal)