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Report error Found 2 Enz. Inhib. hit(s) for PDB: 5UOR
TargetMitogen-activated protein kinase kinase kinase 5(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50212261(CHEMBL3946139)
Affinity DataIC50:  6.30nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged ASK1 catalytic domain (654 to 971 residues) expressed in baculovirus infected sf21 cells using ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedPDB3D3D Structure (crystal)

TargetMitogen-activated protein kinase kinase kinase 5(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50212261(CHEMBL3946139)
Affinity DataEC50:  6.30nMAssay Description:Inhibition of human ASK1 expressed in HEK293 cells assessed as inhibition of H2O2-induced JNK phosphorylation preincubated for 30 mins followed by H2...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedPDB3D3D Structure (crystal)