Compile Data Set for Download or QSAR
maximum 50k data
Found 2 Enz. Inhib. hit(s) for PDB: 5V8O
TargetCyclic GMP-AMP synthase(Homo sapiens)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50250110(CHEMBL4065757)
Affinity DataIC50:  7.80E+4nMAssay Description:Inhibition of human cGAS (2 to 522 residues) expressed in Sf9 insect cells assessed as reduction in cGAMP level using ISD DNA as substrate in presenc...More data for this Ligand-Target Pair
TargetCyclic GMP-AMP synthase(Homo sapiens)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50250110(CHEMBL4065757)
Affinity DataKd:  1.71E+5nMAssay Description:Inhibition of human cGAS (2 to 522 residues) expressed in Sf9 insect cells assessed as reduction in cGAMP level using ISD DNA as substrate in presenc...More data for this Ligand-Target Pair