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Report error Found 5 Enz. Inhib. hit(s) for PDB: 6BMX
TargetTyrosine-protein phosphatase non-receptor type 11(Human)
Soochow University

Curated by ChEMBL
LigandPNGBDBM50546211(CHEMBL4796034)
Affinity DataIC50:  1.89E+4nMAssay Description:Inhibition of Geranylgeranyl transferase type I from porcine brain tissueMore data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 11(Human)
Soochow University

Curated by ChEMBL
LigandPNGBDBM50546211(CHEMBL4796034)
Affinity DataIC50:  1.89E+4nMAssay Description:Allosteric inhibition of IRS1_pY1172(dPEG8)pY1222 activated-human full length SHP2 (Met1 to Leu525 residues) expressed in Escherichia coli BL21 Star ...More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 11(Human)
Soochow University

Curated by ChEMBL
LigandPNGBDBM50546211(CHEMBL4796034)
Affinity DataIC50:  1.89E+4nMAssay Description:Inhibition of SHP2 (unknown origin)More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 11(Human)
Soochow University

Curated by ChEMBL
LigandPNGBDBM50546211(CHEMBL4796034)
Affinity DataIC50:  6.00E+4nMAssay Description:Allosteric inhibition of wild-type human SHP2 (1 to 535 residues) using DiFMUP and 2p-IRS1 peptide as substrates preincubated for 1 hr and followed b...More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 11(Human)
Soochow University

Curated by ChEMBL
LigandPNGBDBM50546211(CHEMBL4796034)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of SHP2 PTP domain (unknown origin)More data for this Ligand-Target Pair