TargetBromodomain-containing protein 4(Homo sapiens (Human))
Celgene Quanticel Research
Curated by ChEMBL
Celgene Quanticel Research
Curated by ChEMBL
Affinity DataIC50: 50nMAssay Description:Inhibition of His-tagged human BRD4-BD1 using H4K5acK8acK12acK16ac as substrate preincubated for 30 mins followed by substrate addition measured afte...More data for this Ligand-Target Pair
TargetBromodomain-containing protein 4(Homo sapiens (Human))
Celgene Quanticel Research
Curated by ChEMBL
Celgene Quanticel Research
Curated by ChEMBL
Affinity DataIC50: 110nMAssay Description:Inhibition of BRD4-BD1 in human Raji cells assessed as downregulation of MYC gene expression by PCR methodMore data for this Ligand-Target Pair
TargetBromodomain-containing protein 4(Homo sapiens (Human))
Celgene Quanticel Research
Curated by ChEMBL
Celgene Quanticel Research
Curated by ChEMBL
Affinity DataIC50: <500nMpH: 7.3Assay Description:Determination of the IC50 for the heterocyclic derivative BRD4 inhibitors disclosed herein was performed as follows. His-tagged BRD4 was cloned, expr...More data for this Ligand-Target Pair
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