Found 80 Enz. Inhib. hit(s) for PDB: 6D6T TargetGamma-aminobutyric acid receptor subunit alpha-1 [G157C]/beta-2 [26-512]/gamma-2 [40-467](Homo sapiens (Human))
University Of Wisconsin At Madison
University Of Wisconsin At Madison
Affinity DataKi: 0.190nM ΔG°: -55.5kJ/moleT: 2°CAssay Description:Membrane homogenates were incubated at room temperature with a sub-Kd concentration of radioligand in the absence or presence of seven different conc...More data for this Ligand-Target Pair
3D Structure (crystal)TargetGamma-aminobutyric acid receptor subunit alpha-1(Homo sapiens (Human))
UniversitÄT Heidelberg
Curated by PDSP Ki Database
UniversitÄT Heidelberg
Curated by PDSP Ki Database
TargetGamma-aminobutyric acid receptor subunit alpha-1(Homo sapiens (Human))
UniversitÄT Heidelberg
Curated by PDSP Ki Database
UniversitÄT Heidelberg
Curated by PDSP Ki Database
TargetGamma-aminobutyric acid receptor subunit alpha-1/beta-2/gamma-2(Rattus norvegicus (Rat))
Heidelberg
Curated by ChEMBL
Heidelberg
Curated by ChEMBL
Affinity DataKi: 0.5nMAssay Description:Binding affinity for rat GABA-A receptor alpha-1-beta-2-gamma-2 subunits expressed in HEK293 cellsMore data for this Ligand-Target Pair
TargetGABA-A receptor; alpha-5/beta-3/gamma-2(Homo sapiens (Human))
University Of Wisconsin-Milwaukee
Curated by ChEMBL
University Of Wisconsin-Milwaukee
Curated by ChEMBL
Affinity DataKi: 0.600nMAssay Description:Binding affinity for Gamma-aminobutyric-acid A receptor alpha5-beta3-gamma2More data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-3/beta-2/gamma-2(Rattus norvegicus (Rat))
Heidelberg
Curated by ChEMBL
Heidelberg
Curated by ChEMBL
Affinity DataKi: 0.600nMAssay Description:Binding affinity for rat GABA-A receptor alpha-3-beta-2-gamma-2 subunits expressed in HEK293 cellsMore data for this Ligand-Target Pair
TargetGABA-A receptor; alpha-5/beta-3/gamma-2(Homo sapiens (Human))
University Of Wisconsin-Milwaukee
Curated by ChEMBL
University Of Wisconsin-Milwaukee
Curated by ChEMBL
Affinity DataKi: 0.600nMAssay Description:Binding affinity for human recombinant gamma-aminobutyric-acid (GABA) A receptor alpha-5-beta-3-gamma-2More data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-1/beta-3/gamma-2(Homo sapiens (Human))
University Of Wisconsin-Milwaukee
Curated by ChEMBL
University Of Wisconsin-Milwaukee
Curated by ChEMBL
Affinity DataKi: 0.800nMAssay Description:Binding affinity for human recombinant gamma-aminobutyric-acid (GABA) A receptor alpha-1-beta-3-gamma-2More data for this Ligand-Target Pair
Target InfoGoogleScholar
TargetGamma-aminobutyric acid receptor subunit alpha-1/beta-3/gamma-2(Homo sapiens (Human))
University Of Wisconsin-Milwaukee
Curated by ChEMBL
University Of Wisconsin-Milwaukee
Curated by ChEMBL
Affinity DataKi: 0.800nMAssay Description:Binding affinity against alpha1-beta3-gamma2 GABAA/BzR receptor subtype.More data for this Ligand-Target Pair
Target InfoGoogleScholar
TargetGamma-aminobutyric acid receptor subunit alpha-1(Rattus norvegicus (Rat))
Tokyo Dental College
Curated by PDSP Ki Database
Tokyo Dental College
Curated by PDSP Ki Database
TargetGABA-A receptor; alpha-2/beta-3/gamma-2(Homo sapiens (Human))
University Of Wisconsin-Milwaukee
Curated by ChEMBL
University Of Wisconsin-Milwaukee
Curated by ChEMBL
Affinity DataKi: 0.900nMAssay Description:Binding affinity to human recombinant gamma-aminobutyric-acid (GABA) A receptor alpha-2-beta-3-gamma-2More data for this Ligand-Target Pair
TargetGABA-A receptor; alpha-2/beta-3/gamma-2(Homo sapiens (Human))
University Of Wisconsin-Milwaukee
Curated by ChEMBL
University Of Wisconsin-Milwaukee
Curated by ChEMBL
Affinity DataKi: 0.900nMAssay Description:Binding affinity of the compound tested against alpha2-beta3-gamma2 GABAA/BzR receptor subtype.More data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-2(Homo sapiens (Human))
UniversitÄT Heidelberg
Curated by PDSP Ki Database
UniversitÄT Heidelberg
Curated by PDSP Ki Database
TargetGamma-aminobutyric acid receptor subunit alpha-3/beta-3/gamma-2(Homo sapiens (Human))
University Of Wisconsin-Milwaukee
Curated by ChEMBL
University Of Wisconsin-Milwaukee
Curated by ChEMBL
Affinity DataKi: 1.10nMAssay Description:Binding affinity against alpha3-beta3-gamma2 GABAA/BzR receptor subtype.More data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-3/beta-3/gamma-2(Homo sapiens (Human))
University Of Wisconsin-Milwaukee
Curated by ChEMBL
University Of Wisconsin-Milwaukee
Curated by ChEMBL
Affinity DataKi: 1.10nMAssay Description:Binding affinity for human recombinant gamma-aminobutyric-acid (GABA) A receptor alpha-3-beta-3-gamma-2More data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-2(Homo sapiens (Human))
UniversitÄT Heidelberg
Curated by PDSP Ki Database
UniversitÄT Heidelberg
Curated by PDSP Ki Database
TargetGamma-aminobutyric acid receptor subunit alpha-1 [V202C]/beta-2 [26-512]/gamma-2 [40-467](Homo sapiens (Human))
University Of Wisconsin At Madison
University Of Wisconsin At Madison
Affinity DataKi: 1.5nM ΔG°: -50.4kJ/moleT: 2°CAssay Description:Membrane homogenates were incubated at room temperature with a sub-Kd concentration of radioligand in the absence or presence of seven different conc...More data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-1(Rattus norvegicus (Rat))
Tokyo Dental College
Curated by PDSP Ki Database
Tokyo Dental College
Curated by PDSP Ki Database
TargetGamma-aminobutyric acid receptor subunit alpha-5 [32-462]/beta-2 [26-512]/gamma-2 [40-467](Homo sapiens (Human))
University Of Wisconsin At Madison
University Of Wisconsin At Madison
Affinity DataKi: 2nM ΔG°: -49.2kJ/molepH: 7.4 T: 2°CAssay Description:Membrane homogenates were incubated at room temperature with a sub-Kd concentration of radioligand in the absence or presence of seven different conc...More data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-1 [T206C]/beta-2 [26-512]/gamma-2 [40-467](Homo sapiens (Human))
University Of Wisconsin At Madison
University Of Wisconsin At Madison
Affinity DataKi: 2.10nM ΔG°: -49.5kJ/moleT: 2°CAssay Description:Membrane homogenates were incubated at room temperature with a sub-Kd concentration of radioligand in the absence or presence of seven different conc...More data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-1 [T162C]/beta-2 [26-512]/gamma-2 [40-467](Homo sapiens (Human))
University Of Wisconsin At Madison
University Of Wisconsin At Madison
Affinity DataKi: 2.20nM ΔG°: -49.4kJ/moleT: 2°CAssay Description:Membrane homogenates were incubated at room temperature with a sub-Kd concentration of radioligand in the absence or presence of seven different conc...More data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-1(Homo sapiens (Human))
UniversitÄT Heidelberg
Curated by PDSP Ki Database
UniversitÄT Heidelberg
Curated by PDSP Ki Database
TargetGamma-aminobutyric acid receptor subunit alpha-1 [G200C]/beta-2 [26-512]/gamma-2 [40-467](Homo sapiens (Human))
University Of Wisconsin At Madison
University Of Wisconsin At Madison
Affinity DataKi: 3nM ΔG°: -48.6kJ/moleT: 2°CAssay Description:Membrane homogenates were incubated at room temperature with a sub-Kd concentration of radioligand in the absence or presence of seven different conc...More data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-1 [28-456]/beta-2 [26-512]/gamma-2 [40-467,D95C](Homo sapiens (Human))
University Of Wisconsin At Madison
University Of Wisconsin At Madison
Affinity DataKi: 3.10nM ΔG°: -48.6kJ/moleT: 2°CAssay Description:Membrane homogenates were incubated at room temperature with a sub-Kd concentration of radioligand in the absence or presence of seven different conc...More data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-1 [28-456]/beta-2 [26-512]/gamma-2 [40-467,R224C](Homo sapiens (Human))
University Of Wisconsin At Madison
University Of Wisconsin At Madison
Affinity DataKi: 3.30nM ΔG°: -48.4kJ/moleT: 2°CAssay Description:Membrane homogenates were incubated at room temperature with a sub-Kd concentration of radioligand in the absence or presence of seven different conc...More data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-1 [28-456]/beta-2 [26-512]/gamma-2 [40-467](Homo sapiens (Human))
University Of Wisconsin At Madison
University Of Wisconsin At Madison
Affinity DataKi: 3.30nM ΔG°: -47.9kJ/molepH: 7.4 T: 2°CAssay Description:Membrane homogenates were incubated at room temperature with a sub-Kd concentration of radioligand in the absence or presence of seven different conc...More data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-1 [28-456]/beta-2 [26-512]/gamma-2 [40-467,R183C](Homo sapiens (Human))
University Of Wisconsin At Madison
University Of Wisconsin At Madison
Affinity DataKi: 3.70nM ΔG°: -48.1kJ/moleT: 2°CAssay Description:Membrane homogenates were incubated at room temperature with a sub-Kd concentration of radioligand in the absence or presence of seven different conc...More data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-1 [28-456]/beta-2 [26-512]/gamma-2 [40-467,L179C](Homo sapiens (Human))
University Of Wisconsin At Madison
University Of Wisconsin At Madison
Affinity DataKi: 3.80nM ΔG°: -48.1kJ/moleT: 2°CAssay Description:Membrane homogenates were incubated at room temperature with a sub-Kd concentration of radioligand in the absence or presence of seven different conc...More data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-1 [A160C]/beta-2 [26-512]/gamma-2 [40-467](Homo sapiens (Human))
University Of Wisconsin At Madison
University Of Wisconsin At Madison
Affinity DataKi: 4nM ΔG°: -47.9kJ/moleT: 2°CAssay Description:Membrane homogenates were incubated at room temperature with a sub-Kd concentration of radioligand in the absence or presence of seven different conc...More data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-1 [V211C]/beta-2 [26-512]/gamma-2 [40-467](Homo sapiens (Human))
University Of Wisconsin At Madison
University Of Wisconsin At Madison
Affinity DataKi: 4.10nM ΔG°: -47.9kJ/moleT: 2°CAssay Description:Membrane homogenates were incubated at room temperature with a sub-Kd concentration of radioligand in the absence or presence of seven different conc...More data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-1 [28-456]/beta-2 [26-512]/gamma-2 [40-467,R233C](Homo sapiens (Human))
University Of Wisconsin At Madison
University Of Wisconsin At Madison
Affinity DataKi: 4.10nM ΔG°: -47.9kJ/moleT: 2°CAssay Description:Membrane homogenates were incubated at room temperature with a sub-Kd concentration of radioligand in the absence or presence of seven different conc...More data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-1 [28-456]/beta-2 [26-512]/gamma-2 [40-467,T120C](Homo sapiens (Human))
University Of Wisconsin At Madison
University Of Wisconsin At Madison
Affinity DataKi: 4.40nM ΔG°: -47.7kJ/moleT: 2°CAssay Description:Membrane homogenates were incubated at room temperature with a sub-Kd concentration of radioligand in the absence or presence of seven different conc...More data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-1 [28-456]/beta-2 [26-512]/gamma-2 [40-467,T165C](Homo sapiens (Human))
University Of Wisconsin At Madison
University Of Wisconsin At Madison
Affinity DataKi: 4.40nM ΔG°: -47.7kJ/moleT: 2°CAssay Description:Membrane homogenates were incubated at room temperature with a sub-Kd concentration of radioligand in the absence or presence of seven different conc...More data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-2 [29-451]/beta-2 [26-512]/gamma-2 [40-467](Homo sapiens (Human))
University Of Wisconsin At Madison
University Of Wisconsin At Madison
Affinity DataKi: 5.70nM ΔG°: -46.6kJ/molepH: 7.4 T: 2°CAssay Description:Membrane homogenates were incubated at room temperature with a sub-Kd concentration of radioligand in the absence or presence of seven different conc...More data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-1 [S205C]/beta-2 [26-512]/gamma-2 [40-467](Homo sapiens (Human))
University Of Wisconsin At Madison
University Of Wisconsin At Madison
Affinity DataKi: 6.5nM ΔG°: -46.7kJ/moleT: 2°CAssay Description:Membrane homogenates were incubated at room temperature with a sub-Kd concentration of radioligand in the absence or presence of seven different conc...More data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-3 [29-492]/beta-2 [26-512]/gamma-2 [40-467](Homo sapiens (Human))
University Of Wisconsin At Madison
University Of Wisconsin At Madison
Affinity DataKi: 8.10nM ΔG°: -45.7kJ/molepH: 7.4 T: 2°CAssay Description:Membrane homogenates were incubated at room temperature with a sub-Kd concentration of radioligand in the absence or presence of seven different conc...More data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-1 [S204C]/beta-2 [26-512]/gamma-2 [40-467](Homo sapiens (Human))
University Of Wisconsin At Madison
University Of Wisconsin At Madison
Affinity DataKi: 8.80nM ΔG°: -46.0kJ/moleT: 2°CAssay Description:Membrane homogenates were incubated at room temperature with a sub-Kd concentration of radioligand in the absence or presence of seven different conc...More data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-1 [28-456]/beta-2 [26-512]/gamma-2 [40-467,T181C](Homo sapiens (Human))
University Of Wisconsin At Madison
University Of Wisconsin At Madison
Affinity DataKi: 9.20nM ΔG°: -45.9kJ/moleT: 2°CAssay Description:Membrane homogenates were incubated at room temperature with a sub-Kd concentration of radioligand in the absence or presence of seven different conc...More data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-1 [28-456]/beta-2 [26-512]/gamma-2 [40-467,A118C](Homo sapiens (Human))
University Of Wisconsin At Madison
University Of Wisconsin At Madison
Affinity DataKi: 9.20nM ΔG°: -45.9kJ/moleT: 2°CAssay Description:Membrane homogenates were incubated at room temperature with a sub-Kd concentration of radioligand in the absence or presence of seven different conc...More data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-1 [28-456]/beta-2 [26-512]/gamma-2 [40-200],P14867[176-456](Homo sapiens (Human))
University Of Wisconsin At Madison
University Of Wisconsin At Madison
Affinity DataKi: 9.60nM ΔG°: -45.8kJ/moleT: 2°CAssay Description:Membrane homogenates were incubated at room temperature with a sub-Kd concentration of radioligand in the absence or presence of seven different conc...More data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-1 [28-456]/beta-2 [26-512]/gamma-2 [40-467,R171C](Homo sapiens (Human))
University Of Wisconsin At Madison
University Of Wisconsin At Madison
Affinity DataKi: 13nM ΔG°: -45.0kJ/moleT: 2°CAssay Description:Membrane homogenates were incubated at room temperature with a sub-Kd concentration of radioligand in the absence or presence of seven different conc...More data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-1 [28-456]/beta-2 [26-512]/gamma-2 [40-467,M169C](Homo sapiens (Human))
University Of Wisconsin At Madison
University Of Wisconsin At Madison
Affinity DataKi: 13.8nM ΔG°: -44.9kJ/moleT: 2°CAssay Description:Membrane homogenates were incubated at room temperature with a sub-Kd concentration of radioligand in the absence or presence of seven different conc...More data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-1(Rattus norvegicus (Rat))
Tokyo Dental College
Curated by PDSP Ki Database
Tokyo Dental College
Curated by PDSP Ki Database
TargetGamma-aminobutyric acid receptor subunit alpha-1 [F99C]/beta-2 [26-512]/gamma-2 [40-467](Homo sapiens (Human))
University Of Wisconsin At Madison
University Of Wisconsin At Madison
Affinity DataKi: 15nM ΔG°: -44.2kJ/molepH: 7.4 T: 2°CAssay Description:Membrane homogenates were incubated at room temperature with a sub-Kd concentration of radioligand in the absence or presence of seven different conc...More data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-6/beta-2/gamma-2(RAT)
Heidelberg
Curated by ChEMBL
Heidelberg
Curated by ChEMBL
Affinity DataKi: 15nMAssay Description:Binding affinity for mutant rat GABA-A receptor alpha-6-(his,thr,gly)beta2gama2 subunits expressed in HEK293 cellsMore data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-6/beta-2/gamma-2(RAT)
Heidelberg
Curated by ChEMBL
Heidelberg
Curated by ChEMBL
Affinity DataKi: 17nMAssay Description:Binding affinity for mutant rat GABA-A receptor alpha-6-(his,thr)beta2gama2 subunits expressed in HEK293 cellsMore data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-6/beta-2/gamma-2(RAT)
Heidelberg
Curated by ChEMBL
Heidelberg
Curated by ChEMBL
Affinity DataKi: 17nMAssay Description:Binding affinity for mutant rat GABA-A receptor alpha-6-(his)-beta-2-gamma-2 subunits expressed in HEK293 cellsMore data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-1(Homo sapiens (Human))
UniversitÄT Heidelberg
Curated by PDSP Ki Database
UniversitÄT Heidelberg
Curated by PDSP Ki Database
TargetGamma-aminobutyric acid receptor subunit alpha-2(Homo sapiens (Human))
UniversitÄT Heidelberg
Curated by PDSP Ki Database
UniversitÄT Heidelberg
Curated by PDSP Ki Database
TargetGamma-aminobutyric acid receptor subunit alpha-1(Rattus norvegicus (Rat))
Tokyo Dental College
Curated by PDSP Ki Database
Tokyo Dental College
Curated by PDSP Ki Database
