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Report error Found 2 Enz. Inhib. hit(s) for PDB: 6NSQ
TargetSerine/threonine-protein kinase B-raf(Human)
University of Southern California

Curated by ChEMBL
LigandPNGBDBM50516816(CHEMBL4593051)
Affinity DataIC50:  8nMAssay Description:Inhibition of recombinant His-tagged BRAF V600E mutant (unknown origin) (444-723 residues) expressed in Escherichia coli BL21(DE3)-RIL using MEKK97R ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMedPDB3D3D Structure (crystal)

TargetSerine/threonine-protein kinase B-raf(Human)
University of Southern California

Curated by ChEMBL
LigandPNGBDBM50516816(CHEMBL4593051)
Affinity DataIC50:  420nMAssay Description:Inhibition of BRAF V600E in human A375 cells assessed as reduction in ERK phosphorylation incubated for 1 hr by immunoblot analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMedPDB3D3D Structure (crystal)