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Report error Found 5 Enz. Inhib. hit(s) for PDB: 6PGR
TargetDeoxyhypusine synthase(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50514710(CHEMBL4555677)
Affinity DataIC50:  62nMAssay Description:Inhibition of human N-terminal His6-tagged TEV protease site linked DHPS expressed in Escherichia coli BL21 (DE3) assessed as reduction in radiolabel...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedPDB3D3D Structure (crystal)

TargetDeoxyhypusine synthase(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50514710(CHEMBL4555677)
Affinity DataIC50:  62nMAssay Description:Displacement of [3H]spermidine trihydrochloride from N-terminal 6his tagged TEV fused human DHPS expressed in Escherichia coli BL21 (DE3) incubated f...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedPDB3D3D Structure (crystal)

TargetDeoxyhypusine synthase(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50514710(CHEMBL4555677)
Affinity DataIC50:  6.90E+3nMAssay Description:Competitive inhibition of human N-terminal His6-tagged TEV protease site linked DHPS expressed in Escherichia coli BL21 (DE3) assessed as reduction i...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedPDB3D3D Structure (crystal)

TargetDeoxyhypusine synthase(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50514710(CHEMBL4555677)
Affinity DataIC50:  5.60E+4nMAssay Description:Displacement of [3H]spermidine trihydrochloride from N-terminal 6his tagged TEV fused human DHPS expressed in Escherichia coli BL21 (DE3) incubated f...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedPDB3D3D Structure (crystal)

TargetDeoxyhypusine synthase(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50514710(CHEMBL4555677)
Affinity DataIC50:  5.60E+4nMAssay Description:Competitive inhibition of human N-terminal His6-tagged TEV protease site linked DHPS expressed in Escherichia coli BL21 (DE3) assessed as reduction i...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedPDB3D3D Structure (crystal)