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Report error Found 2 Enz. Inhib. hit(s) for PDB: 6PZ4
TargetBeta-secretase 1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50510976(CHEMBL4560579)
Affinity DataIC50:  0.400nMAssay Description:Inhibition of BACE1 (unknown origin) using FRET peptide substrate preincubated for 1 hr followed by substrate addition and measured after 1 hr by FRE...More data for this Ligand-Target Pair
TargetBeta-secretase 1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50510976(CHEMBL4560579)
Affinity DataIC50:  1.20nMAssay Description:Inhibition of BACE in HEK293 cells harboring APP Swedish mutant assessed as reduction in amyloid beta 40 level measured after overnight incubation by...More data for this Ligand-Target Pair