TargetMethylosome protein 50/Protein arginine N-methyltransferase 5(Human)
Janssen Pharmaceutica
Curated by ChEMBL
Janssen Pharmaceutica
Curated by ChEMBL
Affinity DataIC50: 9.5nMAssay Description:Inhibition of full-length human N-terminal FLAG-tagged PRMT5/full length N-terminal His6-tagged MEP50 (unknown origin) expressed in baculovirus infec...More data for this Ligand-Target Pair
Affinity DataIC50: 58nMAssay Description:Inhibition of PRMT5 in human A549 cells assessed as reduction in arginine dimethylation of SmD1/3 after 48 hrs by Hoechst Stain/ CellMask Deep Red St...More data for this Ligand-Target Pair