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Report error Found 5 Enz. Inhib. hit(s) for PDB: 6SOV
TargetMitogen-activated protein kinase 14(Human)
King'S College London

Curated by ChEMBL
LigandPNGBDBM15239(4-[4-(4-fluorophenyl)-1-(piperidin-4-yl)-1H-imidaz...)
Affinity DataIC50:  19nMAssay Description:Inhibition of human MAPK p38alphaMore data for this Ligand-Target Pair
In DepthDetails
ArticlePubMedDrugBank
MMDB
PDB3D3D Structure (crystal)
TargetMitogen-activated protein kinase 14(Human)
King'S College London

Curated by ChEMBL
LigandPNGBDBM15239(4-[4-(4-fluorophenyl)-1-(piperidin-4-yl)-1H-imidaz...)
Affinity DataIC50:  19nMpH: 7.5 T: 37°CAssay Description:Kinase activity was assayed in reaction buffer containing substrate, enzyme, and inhibitor in the presence of 0.17 mM ATP/[gamma-32P] ATP. 32P incorp...More data for this Ligand-Target Pair
In DepthDetails
ArticlePubMedDrugBank
MMDB
PDB3D3D Structure (crystal)
TargetMitogen-activated protein kinase 14(Human)
King'S College London

Curated by ChEMBL
LigandPNGBDBM15239(4-[4-(4-fluorophenyl)-1-(piperidin-4-yl)-1H-imidaz...)
Affinity DataIC50:  19nMAssay Description:Inhibition of p38 alpha kinaseMore data for this Ligand-Target Pair
In DepthDetails
ArticlePubMedDrugBank
MMDB
PDB3D3D Structure (crystal)
TargetMitogen-activated protein kinase 14(Human)
King'S College London

Curated by ChEMBL
LigandPNGBDBM15239(4-[4-(4-fluorophenyl)-1-(piperidin-4-yl)-1H-imidaz...)
Affinity DataIC50:  20nMAssay Description:Inhibition against Mitogen-activated protein kinase p38 alphaMore data for this Ligand-Target Pair
In DepthDetails
ArticlePubMedDrugBank
MMDB
PDB3D3D Structure (crystal)
TargetMitogen-activated protein kinase 14(Human)
King'S College London

Curated by ChEMBL
LigandPNGBDBM15239(4-[4-(4-fluorophenyl)-1-(piperidin-4-yl)-1H-imidaz...)
Affinity DataIC50:  20nMAssay Description:Inhibitory concentration against mitogen-activated protein kinase p38 alphaMore data for this Ligand-Target Pair
In DepthDetails
ArticlePubMedDrugBank
MMDB
PDB3D3D Structure (crystal)