Affinity DataIC50: 6.80nMAssay Description:Biochemical IC50 values for the following compounds were determined in accordance with the following protocol (see also Anumala et al., Discovery of ...More data for this Ligand-Target Pair
3D Structure (crystal)Affinity DataIC50: 7nMAssay Description:Biochemical IC50 values for the following compounds were determined in accordance with the following protocol (see also Anumala et al., Discovery of ...More data for this Ligand-Target Pair
Affinity DataIC50: 14nMAssay Description:Inhibition of human TNKS2 (873 to 1162 residues) measured after 20 hrs in presence of NAD+ by fluorescence assayMore data for this Ligand-Target Pair
TargetPoly [ADP-ribose] polymerase tankyrase-1/tankyrase-2(Human)
University of Oslo
Curated by ChEMBL
University of Oslo
Curated by ChEMBL
Affinity DataIC50: 19nMAssay Description:Inhibition of TNKS1/TNKS2 (unknown origin) expressed in HEK293 cells assessed as reduction in Wnt-signaling measured after 24 hrs by dual-glo lucifer...More data for this Ligand-Target Pair
Affinity DataIC50: 126nMAssay Description:Inhibition of recombinant human TNKS1 (1030 to 1317 residues) incubated for 20 hrs in presence of NADMore data for this Ligand-Target Pair
Affinity DataIC50: 127nMAssay Description:Inhibition of human TNKS1 (1030 to 1317 residues) measured after 20 hrs in presence of NAD+ by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 127nMAssay Description:Inhibition of recombinant human TNKS1 (1030 to 1317 residues) incubated for 20 hrs in presence of NADMore data for this Ligand-Target Pair
