Affinity DataIC50: 263nMpH: 7.6Assay Description:S-Adenosyl-L-homocysteine (SAH) was serially diluted 3 fold in DMSO for 10 points and 1 μL was plated in a 384 well microtiter plate. Positive c...More data for this Ligand-Target Pair
3D Structure (crystal)Affinity DataIC50: 263nMpH: 7.6Assay Description:Compound 75 was serially diluted 3 fold in DMSO for 10 points and 1 μL was plated in a 384 well microtiter plate. Positive control (100% inhibit...More data for this Ligand-Target Pair
Affinity DataIC50: 263nMpH: 7.6Assay Description:S-Adenosyl-L-homocysteine (SAH) was serially diluted 3 fold in DMSO for 10 points and 1 μL was plated in a 384 well microtiter plate. Positive c...More data for this Ligand-Target Pair
Affinity DataIC50: 283nMpH: 7.6Assay Description:Compound 75 was serially diluted 3 fold in DMSO for 10 points and 1 μL was plated in a 384 well microtiter plate. Positive control (100% inhibit...More data for this Ligand-Target Pair
Affinity DataIC50: 283nMpH: 7.6Assay Description:S-Adenosyl-L-homocysteine (SAH) was serially diluted 3 fold in DMSO for 10 points and 1 μL was plated in a 384 well microtiter plate. Positive c...More data for this Ligand-Target Pair
Affinity DataIC50: 283nMpH: 7.6Assay Description:S-Adenosyl-L-homocysteine (SAH) was serially diluted 3 fold in DMSO for 10 points and 1 μL was plated in a 384 well microtiter plate. Positive c...More data for this Ligand-Target Pair
Affinity DataIC50: 380nMpH: 7.6Assay Description:Compound 75 was serially diluted 3 fold in DMSO for 10 points and 1 μL was plated in a 384 well microtiter plate. Positive control (100% inhibit...More data for this Ligand-Target Pair
Affinity DataIC50: 380nMpH: 7.6Assay Description:S-Adenosyl-L-homocysteine (SAH) was serially diluted 3 fold in DMSO for 10 points and 1 μL was plated in a 384 well microtiter plate. Positive c...More data for this Ligand-Target Pair
Affinity DataIC50: 380nMpH: 7.6Assay Description:S-Adenosyl-L-homocysteine (SAH) was serially diluted 3 fold in DMSO for 10 points and 1 μL was plated in a 384 well microtiter plate. Positive c...More data for this Ligand-Target Pair
Affinity DataIC50: 467nMpH: 7.6Assay Description:Compound 75 was serially diluted 3 fold in DMSO for 10 points and 1 μL was plated in a 384 well microtiter plate. Positive control (100% inhibit...More data for this Ligand-Target Pair
Affinity DataIC50: 467nMpH: 7.6Assay Description:S-Adenosyl-L-homocysteine (SAH) was serially diluted 3 fold in DMSO for 10 points and 1 μL was plated in a 384 well microtiter plate. Positive c...More data for this Ligand-Target Pair
Affinity DataIC50: 467nMpH: 7.6Assay Description:S-Adenosyl-L-homocysteine (SAH) was serially diluted 3 fold in DMSO for 10 points and 1 μL was plated in a 384 well microtiter plate. Positive c...More data for this Ligand-Target Pair
Affinity DataIC50: 4.80E+3nMpH: 7.6Assay Description:S-Adenosyl-L-homocysteine (SAH) was serially diluted 3 fold in DMSO for 10 points and 1 μL was plated in a 384 well microtiter plate. Positive c...More data for this Ligand-Target Pair
Affinity DataIC50: 4.80E+3nMpH: 7.6Assay Description:S-Adenosyl-L-homocysteine (SAH) was serially diluted 3 fold in DMSO for 10 points and 1 μL was plated in a 384 well microtiter plate. Positive c...More data for this Ligand-Target Pair
Affinity DataIC50: 4.80E+3nMpH: 7.6Assay Description:Compound 75 was serially diluted 3 fold in DMSO for 10 points and 1 μL was plated in a 384 well microtiter plate. Positive control (100% inhibit...More data for this Ligand-Target Pair
Affinity DataIC50: 5.90E+3nMAssay Description:Test compounds were serially diluted 3-fold in DMSO in a 10 point-curve and 1 uL was spotted into a 384-well microplate in duplicate using a Platemat...More data for this Ligand-Target Pair
Affinity DataIC50: 6.24E+3nMAssay Description:Test compounds were serially diluted 3-fold in DMSO in a 10 point-curve and 1 uL was spotted into a 384-well microplate in duplicate using a Platemat...More data for this Ligand-Target Pair
Affinity DataIC50: 6.91E+3nMAssay Description:Test compounds were serially diluted 3-fold in DMSO in a 10 point-curve and 1 uL was spotted into a 384-well microplate in duplicate using a Platemat...More data for this Ligand-Target Pair
Affinity DataIC50: 1.10E+4nMAssay Description:Inhibition of N-terminally FLAG-tagged wild type EZH2 in EZH2/SUZ12/EED/RbAp48 complex (unknown origin) expressed in baculovirus infected in SF9 cell...More data for this Ligand-Target Pair
Affinity DataIC50: 1.66E+4nMAssay Description:Test compounds were serially diluted 3-fold in DMSO in a 10 point-curve and 1 uL was spotted into a 384-well microplate in duplicate using a Platemat...More data for this Ligand-Target Pair
Affinity DataIC50: 2.26E+4nMAssay Description:Inhibition of recombinant human EZH2 using core histone as substrate by hotspot assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2.37E+4nMAssay Description:Inhibition of EZH2 (unknown origin) using [3H]SAM and chicken core histone as substrates incubated for 1 hrMore data for this Ligand-Target Pair
Affinity DataIC50: 6.50E+4nMAssay Description:Inhibition of EZH2 (unknown origin)More data for this Ligand-Target Pair
