BindingDB PrimarySearch

Report error Found 2 Enz. Inhib. hit(s) for PDB: 6XRM

Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform(Human)
Arcus Biosciences

Curated by ChEMBL

BDBM50546730(CHEMBL4782083)

IC50: 1.90nMAssay Description:Inhibition of recombinant N-terminal His-tagged full-length human PI3K p120gamma expressed in Sf9 insect cells using phosphatidylinositol 4,5-bisphos...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

PC cid PC sid PDB

Details Article PubMed PDB

3D Structure (crystal)

Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform(Human)
Arcus Biosciences

Curated by ChEMBL

BDBM50546730(CHEMBL4782083)

IC50: 64nMAssay Description:Inhibition of PI3Kgamma in human THP-1 cells assessed as reduction in Akt phosphorylation at S473 residue incubated for 60 mins by alphalisa assayMore data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

PC cid PC sid PDB

Details Article PubMed PDB

3D Structure (crystal)