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Report error Found 10 Enz. Inhib. hit(s) for PDB: 6YOJ
TargetFocal adhesion kinase 1(Human)TBA
LigandPNGBDBM50269948(6-(4-(3-(methylsulfonyl)benzylamino)-5-(trifluorom...)
Affinity DataIC50:  4nMAssay Description:Inhibition of FAK (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePDB3D3D Structure (crystal)

TargetFocal adhesion kinase 1(Human)TBA
LigandPNGBDBM50269948(6-(4-(3-(methylsulfonyl)benzylamino)-5-(trifluorom...)
Affinity DataIC50:  4nMAssay Description:Inhibition of recombinant FAK (410 to 689 residues) (unknown origin) in presence of ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedPDB3D3D Structure (crystal)

TargetFocal adhesion kinase 1(Human)TBA
LigandPNGBDBM50269948(6-(4-(3-(methylsulfonyl)benzylamino)-5-(trifluorom...)
Affinity DataIC50:  4nMAssay Description:Inhibition of recombinant FAK (410 to 689 residues) (unknown origin) using Poly (4:1 Glu, Tyr) peptide as substrate enzyme pretreated with substrate ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedPDB3D3D Structure (crystal)

TargetFocal adhesion kinase 1(Human)TBA
LigandPNGBDBM50269948(6-(4-(3-(methylsulfonyl)benzylamino)-5-(trifluorom...)
Affinity DataIC50:  4nMAssay Description:Inhibition of FAK (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedPDB3D3D Structure (crystal)

TargetFocal adhesion kinase 1(Human)TBA
LigandPNGBDBM50269948(6-(4-(3-(methylsulfonyl)benzylamino)-5-(trifluorom...)
Affinity DataIC50:  4nMAssay Description:Inhibition of GST-FAK domain (410-689) (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedPDB3D3D Structure (crystal)

TargetFocal adhesion kinase 1(Human)TBA
LigandPNGBDBM50269948(6-(4-(3-(methylsulfonyl)benzylamino)-5-(trifluorom...)
Affinity DataIC50:  11nMAssay Description:Inhibition of FAK Tyr397 phosphorylation in human A431 cells by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedPDB3D3D Structure (crystal)

TargetFocal adhesion kinase 1(Human)TBA
LigandPNGBDBM50269948(6-(4-(3-(methylsulfonyl)benzylamino)-5-(trifluorom...)
Affinity DataIC50:  30nMAssay Description:Inhibition of FAK Tyr397 phosphorylation in human FG cells after 60 mins by western blot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedPDB3D3D Structure (crystal)

TargetFocal adhesion kinase 1(Human)TBA
LigandPNGBDBM50269948(6-(4-(3-(methylsulfonyl)benzylamino)-5-(trifluorom...)
Affinity DataIC50:  50nMAssay Description:Inhibition of FAK Tyr397 phosphorylation in human SKOV3 cells after 60 mins by western blot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedPDB3D3D Structure (crystal)

TargetFocal adhesion kinase 1(Human)TBA
LigandPNGBDBM50269948(6-(4-(3-(methylsulfonyl)benzylamino)-5-(trifluorom...)
Affinity DataIC50:  100nMAssay Description:Inhibition of FAK Tyr397 phosphorylation in human PC3 cells after 60 mins by western blot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedPDB3D3D Structure (crystal)

TargetFocal adhesion kinase 1(Human)TBA
LigandPNGBDBM50269948(6-(4-(3-(methylsulfonyl)benzylamino)-5-(trifluorom...)
Affinity DataIC50:  300nMAssay Description:Inhibition of FAK Tyr397 phosphorylation in human L3.6pl cells after 60 mins by western blot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedPDB3D3D Structure (crystal)