BindingDB PrimarySearch

Report error Found 3 Enz. Inhib. hit(s) for PDB: 6ZAD

Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Human)
Gsk Medicines Research Centre

Curated by ChEMBL

BDBM50543037(CHEMBL4638471)

IC50: 20nMAssay Description:Inhibition of PI3Kdelta (unknown origin)More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

PC cid PC sid PDB

Details Article PubMed PDB

3D Structure (crystal)

Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Human)
Gsk Medicines Research Centre

Curated by ChEMBL

BDBM50543037(CHEMBL4638471)

IC50: 316nMAssay Description:Inhibition of PI3Kdelta in whole blood (unknown origin) assessed as reduction in cytostim-induced IFNgamma productionMore data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

PC cid PC sid PDB

Details Article PubMed PDB

3D Structure (crystal)

Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Human)
Gsk Medicines Research Centre

Curated by ChEMBL

BDBM50543037(CHEMBL4638471)

Kd: 4nMAssay Description:Binding affinity to PI3Kdelta (unknown origin) by SPR based van't Hoff analysisMore data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

PC cid PC sid PDB

Details Article PubMed PDB

3D Structure (crystal)