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Report error Found 3 Enz. Inhib. hit(s) for PDB: 6ZBA
LigandPNGBDBM50548531(CHEMBL4747201)
Affinity DataIC50:  1.20nMAssay Description:Inhibition of human PDE4B catalytic domain using cAMP and FAM-conjugated cAMP by IMAP FRET progressive binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedPDB3D3D Structure (crystal)

LigandPNGBDBM50548531(CHEMBL4747201)
Affinity DataIC50:  3.80nMAssay Description:Inhibition of human PDE4D catalytic domain using cAMP and FAM-conjugated cAMP by IMAP FRET progressive binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedPDB3D3D Structure (crystal)

LigandPNGBDBM50548531(CHEMBL4747201)
Affinity DataIC50:  6nMAssay Description:Inhibition of PDE4D in human PBMC assessed as reduction in lipopolysaccharide-induced TNFalpha production pre-incubated for 30 mins before LPS stimul...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedPDB3D3D Structure (crystal)