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Report error Found 2 Enz. Inhib. hit(s) for PDB: 7A4W

Dual specificity tyrosine-phosphorylation-regulated kinase 1A(Human)
Vernalis (R&D)

Curated by ChEMBL

BDBM50381865(CHEMBL2023701)

Ki: 100nMAssay Description:Binding affinity to DYRK1A (unknown origin) assessed as inhibition constant by ADP hunter plus assayMore data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

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3D Structure (crystal)

Dual specificity tyrosine-phosphorylation-regulated kinase 1A(Human)
Vernalis (R&D)

Curated by ChEMBL

BDBM50381865(CHEMBL2023701)

IC50: 158nMAssay Description:Inhibition of DYRK1A (unknown origin) using Ulight-MBP as substrate and ATP as co-substrate incubated for 40 mins and measured after 1 hr by TR-FRET ...More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Purchase CHEMBL PC cid PC sid PDB

Details
Article PubMed PDB

3D Structure (crystal)