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Report error Found 3 Enz. Inhib. hit(s) for PDB: 7AS1
TargetPolymerase basic protein 2(Influenza A virus (strain A/Puerto Rico/8/1934 H1N...)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50050712(CHEMBL3318007)
Affinity DataIC50:  4nMAssay Description:Inhibition of influenza A virus polymerase PB2 expressed in HEK293T cells cotransfected with PGK-renilla-luciferase pretreated with cells for 2 hrs f...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedPDB3D3D Structure (crystal)

TargetPolymerase basic protein 2(Influenza A virus (strain A/Puerto Rico/8/1934 H1N...)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50050712(CHEMBL3318007)
Affinity DataEC50:  0.600nMAssay Description:Inhibition of PB2 in Influenza A virus (A/Weiss/1943(H1N1)) infected in MDCK cells assessed as reduction in virus induced cell death after 5 days by ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedPDB3D3D Structure (crystal)

TargetPolymerase basic protein 2(Influenza A virus (strain A/Puerto Rico/8/1934 H1N...)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50050712(CHEMBL3318007)
Affinity DataKd:  54nMAssay Description:Binding affinity to CM5 immobilized N-terminal His/Sumo tagged Influenza A virus (A/WSN/1933(H1N1)) PB2 CBD (318 to 486 residues) expressed in Escher...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedPDB3D3D Structure (crystal)