Compile Data Set for Download or QSAR
maximum 50k data
Report error Found 8 Enz. Inhib. hit(s) for PDB: 7CXA
TargetGalectin-3(Human)
Bristol Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50581762(GB-0139 | GB0139 | OLITIGALTIN | Olitigaltin | TD-...)
Affinity DataIC50:  10nMAssay Description:Inhibition of biotin-asialofetuin binding to human Gal3 measured after 90 mins by HTRF competition assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMedPDB3D3D Structure (crystal)

TargetGalectin-3(Mouse)
Bristol Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50581762(GB-0139 | GB0139 | OLITIGALTIN | Olitigaltin | TD-...)
Affinity DataIC50:  67nMAssay Description:Inhibition of biotin-asialofetuin binding to mouse Gal3 measured after 90 mins by HTRF competition assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMedPDB3D3D Structure (crystal)

TargetGalectin-3(Human)
Bristol Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50581762(GB-0139 | GB0139 | OLITIGALTIN | Olitigaltin | TD-...)
Affinity DataIC50:  80nMAssay Description:Inhibition of human Gal3-induced chemotaxis using human monocyte incubated for 4 hrs by calcein-AM dye based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMedPDB3D3D Structure (crystal)

TargetGalectin-3(Mouse)
Bristol Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50581762(GB-0139 | GB0139 | OLITIGALTIN | Olitigaltin | TD-...)
Affinity DataIC50:  300nMAssay Description:Inhibition of moues Gal3-induced hemagglutination using mouse RBC incubated for overnight by hemagglutination assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMedPDB3D3D Structure (crystal)

TargetGalectin-3(Human)
Bristol Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50581762(GB-0139 | GB0139 | OLITIGALTIN | Olitigaltin | TD-...)
Affinity DataKd:  2.30nMAssay Description:Binding affinity to galectin-3 (unknown origin) assessed as dissociation constantMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMedPDB3D3D Structure (crystal)

TargetGalectin-3(Human)
Bristol Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50581762(GB-0139 | GB0139 | OLITIGALTIN | Olitigaltin | TD-...)
Affinity DataKd:  2.20nMAssay Description:Binding affinity at recombinant human Galectin-3 assessed as dissociation constant by fluorescence anisotropy assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMedPDB3D3D Structure (crystal)

TargetGalectin-3(Human)
Bristol Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50581762(GB-0139 | GB0139 | OLITIGALTIN | Olitigaltin | TD-...)
Affinity DataKd:  37nMAssay Description:Binding affinity to human Gal-3 expressed in Escherichia coli BL21 (DE3) cells by competitive fluorescence polarization assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMedPDB3D3D Structure (crystal)

TargetGalectin-3(Human)
Bristol Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50581762(GB-0139 | GB0139 | OLITIGALTIN | Olitigaltin | TD-...)
Affinity DataKd:  14nMAssay Description:Binding affinity to human Gal-3 expressed in Escherichia coli BL21star (DE3) cells by competitive fluorescence polarization assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMedPDB3D3D Structure (crystal)