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Report error Found 1 Enz. Inhib. hit(s) for PDB: 7NA1
TargetE3 ubiquitin-protein ligase Mdm2 [17-125](Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM215010(8-(1-benzo- thiophen-5-yl)- 7-(4-chloro- benzyl)-6...)
Affinity DataIC50:  259nMT: 25°CAssay Description:An HDM2 FRET assay was developed to assess the compounds' inhibitory activity towards binding of p53 protein. A truncated version of HDM2 with re...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB