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Report error Found 6 Enz. Inhib. hit(s) for PDB: 7OCE
TargetGlutamate receptor 2(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50207594(2,3-Dihydroxy-6-nitro-benzo[f]quinoxaline-7-sulfon...)
Affinity DataKi:  210nMAssay Description:Inhibition of [3H]-AMPA binding to human GluR2 receptors expressed in HEK 293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedPDB3D3D Structure (crystal)

TargetGlutamate receptor 2(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50207594(2,3-Dihydroxy-6-nitro-benzo[f]quinoxaline-7-sulfon...)
Affinity DataKi:  260nMAssay Description:Ability to displace binding of [3H]AMPA to recombinant human Ionotropic glutamate receptor AMPA 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedPDB3D3D Structure (crystal)

TargetGlutamate receptor 1(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50207594(2,3-Dihydroxy-6-nitro-benzo[f]quinoxaline-7-sulfon...)
Affinity DataKi:  1.60E+3nMAssay Description:Ability to displace binding of [3H]AMPA to recombinant human Ionotropic glutamate receptor AMPA 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedPDB3D3D Structure (crystal)

TargetGlutamate receptor 2(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50207594(2,3-Dihydroxy-6-nitro-benzo[f]quinoxaline-7-sulfon...)
Affinity DataIC50:  2.50E+3nMAssay Description:Antagonist activity at human recombinant GLUA2-AMPA receptor expressed in HEK293 cells assessed as inhibition of glutamate-stimulated calcium influx ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedPDB3D3D Structure (crystal)

TargetGlutamate receptor 2(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50207594(2,3-Dihydroxy-6-nitro-benzo[f]quinoxaline-7-sulfon...)
Affinity DataIC50:  2.50E+3nMAssay Description:Inhibition of glutamate-induced calcium influx in HEK293 cells expressing human GLUA2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedPDB3D3D Structure (crystal)

TargetGlutamate receptor 1(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50207594(2,3-Dihydroxy-6-nitro-benzo[f]quinoxaline-7-sulfon...)
Affinity DataIC50:  6.00E+3nMAssay Description:Inhibition of glutamate-induced calcium influx in HEK293 cells expressing human GLUA1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedPDB3D3D Structure (crystal)