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Report error Found 6 Enz. Inhib. hit(s) for PDB: 7SLX
TargetPantetheinase(Human)
Pfizer

US Patent
LigandPNGBDBM480978(US10906888, Example 195 | US10906888, Example 196 ...)
Affinity DataIC50:  5.22nMAssay Description:The test inhibitors were solubilized in DMSO to a stock concentration of 30 mM. On the day of the assay, dose response plates were prepared by diluti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetPantetheinase(Human)
Pfizer

US Patent
LigandPNGBDBM480978(US10906888, Example 195 | US10906888, Example 196 ...)
Affinity DataIC50:  10nMAssay Description:Inhibition of recombinant N-terminal FLAG/His6-tagged human vanin-1 expressed in CHO cells using Pantetheine-7-amino-4-trifluoromethykournarin as sub...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetPantetheinase(Human)
Pfizer

US Patent
LigandPNGBDBM480978(US10906888, Example 195 | US10906888, Example 196 ...)
Affinity DataIC50:  10.7nMAssay Description:The test inhibitors were solubilized in DMSO to a stock concentration of 30 mM. On the day of the assay, dose response plates were prepared by diluti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetPantetheinase(Human)
Pfizer

US Patent
LigandPNGBDBM480978(US10906888, Example 195 | US10906888, Example 196 ...)
Affinity DataIC50:  45nMAssay Description:Inhibition of recombinant N-terminal FLAG/His6-tagged human vanin-1 expressed in CHO cells at 10 uM by 1H NMR analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetPantetheinase(Human)
Pfizer

US Patent
LigandPNGBDBM480978(US10906888, Example 195 | US10906888, Example 196 ...)
Affinity DataIC50:  1.18E+3nMAssay Description:The test inhibitors were solubilized in DMSO to a stock concentration of 30 mM. On the day of the assay, dose response plates were prepared by diluti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetPantetheinase(Human)
Pfizer

US Patent
LigandPNGBDBM480978(US10906888, Example 195 | US10906888, Example 196 ...)
Affinity DataKd:  7.20nMAssay Description:Binding affinity to recombinant N-terminal FLAG/His6-tagged human vanin-1 expressed in CHO cells assessed as dissociation constant by surface plasmon...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB