Compile Data Set for Download or QSAR
maximum 50k data
Report error Found 10 Enz. Inhib. hit(s) for PDB: 7SQO
TargetOrexin receptor type 2(Human)
Takeda Pharmaceutical

US Patent
LigandPNGBDBM386067(US10287305, Example 5 | US10508083, Example 191 | ...)
Affinity DataEC50:  2.20nMAssay Description:Chinese hamster ovary (CHO) dhfr-cells forcibly expressing human orexin type 2 receptor (hOX2R) were seeded in each well of Black clear bottom plate ...More data for this Ligand-Target Pair
In DepthDetails US Patent
PDB3D3D Structure (crystal)

TargetOrexin receptor type 2(Human)
Takeda Pharmaceutical

US Patent
LigandPNGBDBM386216(US10287305, Example 191 | methyl-d3 (2R,3S)-3- ((m...)
Affinity DataEC50:  2.90nMAssay Description:Chinese hamster ovary (CHO) dhfr-cells forcibly expressing human orexin type 2 receptor (hOX2R) were seeded in each well of Black clear bottom plate ...More data for this Ligand-Target Pair
In DepthDetails US Patent
PDB3D3D Structure (crystal)

TargetOrexin receptor type 2(Human)
Takeda Pharmaceutical

US Patent
LigandPNGBDBM386067(US10287305, Example 5 | US10508083, Example 191 | ...)
Affinity DataEC50:  2.20nMAssay Description:Chinese hamster ovary (CHO) dhfr-cells forcibly expressing human orexin type 2 receptor (hOX2R) were seeded in each well of Black clear bottom plate ...More data for this Ligand-Target Pair
In DepthDetails US Patent
PDB3D3D Structure (crystal)

TargetOrexin receptor type 2(Human)
Takeda Pharmaceutical

US Patent
LigandPNGBDBM386067(US10287305, Example 5 | US10508083, Example 191 | ...)
Affinity DataEC50:  2.90nMAssay Description:Chinese hamster ovary (CHO) dhfr-cells forcibly expressing human orexin type 2 receptor (hOX2R) were seeded in each well of Black clear bottom plate ...More data for this Ligand-Target Pair
In DepthDetails US Patent
PDB3D3D Structure (crystal)

TargetOrexin receptor type 2(Human)
Takeda Pharmaceutical

US Patent
LigandPNGBDBM386067(US10287305, Example 5 | US10508083, Example 191 | ...)
Affinity DataEC50:  5.5nMAssay Description:Agonist activity at OX2R (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedPDB3D3D Structure (crystal)

TargetOrexin receptor type 2(Human)
Takeda Pharmaceutical

US Patent
LigandPNGBDBM386067(US10287305, Example 5 | US10508083, Example 191 | ...)
Affinity DataEC50:  2.90nMAssay Description:Chinese hamster ovary (CHO) dhfr-cells forcibly expressing human orexin type 2 receptor (hOX2R) were seeded in each well of Black clear bottom plate ...More data for this Ligand-Target Pair
In DepthDetails US Patent
PDB3D3D Structure (crystal)

TargetOrexin receptor type 2(Human)
Takeda Pharmaceutical

US Patent
LigandPNGBDBM386067(US10287305, Example 5 | US10508083, Example 191 | ...)
Affinity DataEC50:  5.5nMAssay Description:Agonist activity at human OX2R expressed in CHO-K1 cells by FLIPR calcium flux assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedPDB3D3D Structure (crystal)

TargetOrexin receptor type 2(Human)
Takeda Pharmaceutical

US Patent
LigandPNGBDBM386067(US10287305, Example 5 | US10508083, Example 191 | ...)
Affinity DataEC50:  5.50E+3nMAssay Description:Agonist activity at human OX2R stably expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedPDB3D3D Structure (crystal)

TargetOrexin receptor type 2(Human)
Takeda Pharmaceutical

US Patent
LigandPNGBDBM386067(US10287305, Example 5 | US10508083, Example 191 | ...)
Affinity DataEC50:  5.5nMAssay Description:Agonist activity at human OX2R expressed in CHO-K1 cells assessed as increase in calcium mobilization by Fluo-4-AM dye based fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedPDB3D3D Structure (crystal)

TargetOrexin receptor type 2(Human)
Takeda Pharmaceutical

US Patent
LigandPNGBDBM386067(US10287305, Example 5 | US10508083, Example 191 | ...)
Affinity DataEC50:  2.20nMAssay Description:Chinese hamster ovary (CHO) dhfr-cells forcibly expressing human orexin type 2 receptor (hOX2R) were seeded in each well of Black clear bottom plate ...More data for this Ligand-Target Pair
In DepthDetails US Patent
PDB3D3D Structure (crystal)