Compile Data Set for Download or QSAR
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Report error Found 8 Enz. Inhib. hit(s) for PDB: 8AN8
TargetHepatocyte growth factor receptor(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50609348(CHEMBL5272595)
Affinity DataIC50:  90nMAssay Description:Inhibition of his-tagged c-MET D1228V mutant (1050 to 1346 residues) (unknown origin) by ADP-glo assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMedPDB3D3D Structure (crystal)

TargetHepatocyte growth factor receptor(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50609348(CHEMBL5272595)
Affinity DataIC50:  900nMAssay Description:Inhibition of his-tagged wild type c-MET (1050 to 1346 residues) (unknown origin) by ADP-glo assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMedPDB3D3D Structure (crystal)

TargetHepatocyte growth factor receptor(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50609348(CHEMBL5272595)
Affinity DataIC50:  1.20E+4nMAssay Description:Inhibition of his-tagged c-MET D1228V mutant (1050 to 1346 residues) (unknown origin) in human NCI-H1993 cells by HTRF analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMedPDB3D3D Structure (crystal)

TargetHepatocyte growth factor receptor(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50609348(CHEMBL5272595)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of his-tagged wild type c-MET (1050 to 1346 residues) (unknown origin) in human NCI-H1993 cells by HTRF analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMedPDB3D3D Structure (crystal)

TargetHepatocyte growth factor receptor(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50609347(CHEMBL5268922)
Affinity DataKd:  1.40E+3nMAssay Description:Binding affinity to his-tagged c-MET D1228V mutant (1050 to 1346 residues) (unknown origin) assessed as dissociation constant by surface plasmon reso...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMedPDB3D3D Structure (crystal)

TargetHepatocyte growth factor receptor(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50609348(CHEMBL5272595)
Affinity DataKd:  7.20E+3nMAssay Description:Binding affinity to his-tagged wild type c-MET (1050 to 1346 residues) (unknown origin) by surface plasmon resonance analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMedPDB3D3D Structure (crystal)

TargetHepatocyte growth factor receptor(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50609347(CHEMBL5268922)
Affinity DataKd: >2.00E+4nMAssay Description:Binding affinity to his-tagged wild type c-MET (1050 to 1346 residues) (unknown origin) by surface plasmon resonance analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMedPDB3D3D Structure (crystal)

TargetHepatocyte growth factor receptor(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50609348(CHEMBL5272595)
Affinity DataKd:  650nMAssay Description:Binding affinity to his-tagged c-MET D1228V mutant (1050 to 1346 residues) (unknown origin) assessed as dissociation constant by surface plasmon reso...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMedPDB3D3D Structure (crystal)