Compile Data Set for Download or QSAR
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Report error Found 12 Enz. Inhib. hit(s) for PDB: 8AU5
TargetHepatocyte growth factor receptor(Human)
Merck Serono

Curated by ChEMBL
LigandPNGBDBM50065457(EMD-1214063 | MSC-2156119 | MSC-2156119J | Tepotin...)
Affinity DataIC50: <1nMAssay Description:Inhibition of GST-His6-tagged recombinant human c-Met kinase domain (956 to 1390) after 60 mins by anoff-chip mobility shift assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedPDB3D3D Structure (crystal)

TargetHepatocyte growth factor receptor(Human)
Merck Serono

Curated by ChEMBL
LigandPNGBDBM50065457(EMD-1214063 | MSC-2156119 | MSC-2156119J | Tepotin...)
Affinity DataIC50:  3nMAssay Description:Inhibition of c-Met (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedPDB3D3D Structure (crystal)

TargetHepatocyte growth factor receptor(Human)
Merck Serono

Curated by ChEMBL
LigandPNGBDBM50065457(EMD-1214063 | MSC-2156119 | MSC-2156119J | Tepotin...)
Affinity DataIC50:  3.10nMAssay Description:Inhibition of N-terminal His/SUMO tagged wild type human c-Met (1038 to 1346 residues) transfected in Escherichia coli using Tyr06 peptide as substra...More data for this Ligand-Target Pair
In DepthDetails PubMedPDB3D3D Structure (crystal)

TargetHepatocyte growth factor receptor(Human)
Merck Serono

Curated by ChEMBL
LigandPNGBDBM50065457(EMD-1214063 | MSC-2156119 | MSC-2156119J | Tepotin...)
Affinity DataIC50:  12nMAssay Description:Inhibition of c-Met kinase in human A549 cells assessed as inhibition of phosphorylation after 45 mins by electrochemiluminescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedPDB3D3D Structure (crystal)

TargetHepatocyte growth factor receptor(Human)
Merck Serono

Curated by ChEMBL
LigandPNGBDBM50065457(EMD-1214063 | MSC-2156119 | MSC-2156119J | Tepotin...)
Affinity DataIC50: <100nMT: 25°CAssay Description:The test plates used are 96-well Flashplate® microtitre plates from Perkin Elmer (Cat. No. SMP200). The components of the kinase reaction describ...More data for this Ligand-Target Pair
In DepthDetails US Patent
PDB3D3D Structure (crystal)

TargetHepatocyte growth factor receptor(Human)
Merck Serono

Curated by ChEMBL
LigandPNGBDBM50065457(EMD-1214063 | MSC-2156119 | MSC-2156119J | Tepotin...)
Affinity DataIC50: <100nMT: 25°CAssay Description:The test plates used are 96-well Flashplate® microtitre plates from Perkin Elmer (Cat. No. SMP200). The components of the kinase reaction describ...More data for this Ligand-Target Pair
In DepthDetails US Patent
PDB3D3D Structure (crystal)

TargetHepatocyte growth factor receptor(Human)
Merck Serono

Curated by ChEMBL
LigandPNGBDBM50065457(EMD-1214063 | MSC-2156119 | MSC-2156119J | Tepotin...)
Affinity DataIC50: <100nMT: 25°CAssay Description:The test plates used are 96-well Flashplate® microtitre plates from Perkin Elmer (Cat. No. SMP200). The components of the kinase reaction describ...More data for this Ligand-Target Pair
In DepthDetails US Patent
PDB3D3D Structure (crystal)

TargetHepatocyte growth factor receptor(Human)
Merck Serono

Curated by ChEMBL
LigandPNGBDBM50065457(EMD-1214063 | MSC-2156119 | MSC-2156119J | Tepotin...)
Affinity DataIC50: <100nMT: 25°CAssay Description:The test plates used are 96-well Flashplate® microtitre plates from Perkin Elmer (Cat. No. SMP200). The components of the kinase reaction describ...More data for this Ligand-Target Pair
In DepthDetails US Patent
PDB3D3D Structure (crystal)

TargetHepatocyte growth factor receptor(Human)
Merck Serono

Curated by ChEMBL
LigandPNGBDBM50065457(EMD-1214063 | MSC-2156119 | MSC-2156119J | Tepotin...)
Affinity DataIC50: <100nMT: 25°CAssay Description:The test plates used are 96-well Flashplate® microtitre plates from Perkin Elmer (Cat. No. SMP200). The components of the kinase reaction describ...More data for this Ligand-Target Pair
In DepthDetails US Patent
PDB3D3D Structure (crystal)

TargetHepatocyte growth factor receptor(Human)
Merck Serono

Curated by ChEMBL
LigandPNGBDBM50065457(EMD-1214063 | MSC-2156119 | MSC-2156119J | Tepotin...)
Affinity DataIC50: <100nMT: 25°CAssay Description:The test plates used are 96-well Flashplate® microtitre plates from Perkin Elmer (Cat. No. SMP200). The components of the kinase reaction describ...More data for this Ligand-Target Pair
In DepthDetails US Patent
PDB3D3D Structure (crystal)

TargetHepatocyte growth factor receptor(Human)
Merck Serono

Curated by ChEMBL
LigandPNGBDBM50065457(EMD-1214063 | MSC-2156119 | MSC-2156119J | Tepotin...)
Affinity DataIC50: <100nMT: 25°CAssay Description:The test plates used are 96-well Flashplate® microtitre plates from Perkin Elmer (Cat. No. SMP200). The components of the kinase reaction describ...More data for this Ligand-Target Pair
In DepthDetails US Patent
PDB3D3D Structure (crystal)

TargetHepatocyte growth factor receptor(Human)
Merck Serono

Curated by ChEMBL
LigandPNGBDBM50065457(EMD-1214063 | MSC-2156119 | MSC-2156119J | Tepotin...)
Affinity DataIC50: <100nMT: 25°CAssay Description:The test plates used are 96-well Flashplate® microtitre plates from Perkin Elmer (Cat. No. SMP200). The components of the kinase reaction describ...More data for this Ligand-Target Pair
In DepthDetails US Patent
PDB3D3D Structure (crystal)