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Report error Found 2 Enz. Inhib. hit(s) for PDB: 8D6E

Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase(Human)
Repare Therapeutics

Curated by ChEMBL

BDBM50598851(CHEMBL5199076)

IC50: 2nMAssay Description:Inhibition of full length Nano-luc fused PKMYT1 in human HEK-293T cells incubated for 2 hrs by cell based NanoBRET target engagement assayMore data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

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3D Structure (crystal)

Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase(Human)
Repare Therapeutics

Curated by ChEMBL

BDBM50598851(CHEMBL5199076)

IC50: 14nMAssay Description:Inhibition of N-terminal recombinant PKMYT1 (76 to 362 residues) in CCNE1 amplified human FU-OV-1 cells assessed as phosphorylation of CDK1 at Thr14 ...More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar

Purchase PC cid PC sid PDB

Details PubMed PDB

3D Structure (crystal)