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Report error Found 9 Enz. Inhib. hit(s) for PDB: 8R9A
TargetCyclin-dependent kinase 7(Human)
Carrick Therapeutics

US Patent
LigandPNGBDBM50526797(Ct-7001 | Ct7001 | ICEC-0942 | ICEC0942 | Samuraci...)
Affinity DataIC50:  34nMAssay Description:CDK7 IC50 Materials and Solutions:In addition to those mentioned above for Method 1:CDK7/cycH/MAT1 (ProQinase, 0366-0360-4).MnCl2 (Sigma, M1787).CDKt...More data for this Ligand-Target Pair
In DepthDetails US Patent
PDB3D3D Structure (crystal)

TargetCyclin-dependent kinase 7(Human)
Carrick Therapeutics

US Patent
LigandPNGBDBM50526797(Ct-7001 | Ct7001 | ICEC-0942 | ICEC0942 | Samuraci...)
Affinity DataIC50:  34nMAssay Description:CDK7 IC50 Materials and Solutions:In addition to those mentioned above for Method 1:CDK7/cycH/MAT1 (ProQinase, 0366-0360-4).MnCl2 (Sigma, M1787).CDKt...More data for this Ligand-Target Pair
In DepthDetails US Patent
PDB3D3D Structure (crystal)

TargetCyclin-dependent kinase 7(Human)
Carrick Therapeutics

US Patent
LigandPNGBDBM50526797(Ct-7001 | Ct7001 | ICEC-0942 | ICEC0942 | Samuraci...)
Affinity DataIC50:  34nMAssay Description:CDK7 IC50 Materials and Solutions:In addition to those mentioned above for Method 1:CDK7/cycH/MAT1 (ProQinase, 0366-0360-4).MnCl2 (Sigma, M1787).CDKt...More data for this Ligand-Target Pair
In DepthDetails US Patent
PDB3D3D Structure (crystal)

TargetCyclin-dependent kinase 7(Human)
Carrick Therapeutics

US Patent
LigandPNGBDBM50526797(Ct-7001 | Ct7001 | ICEC-0942 | ICEC0942 | Samuraci...)
Affinity DataIC50:  40nMAssay Description:Inhibition of CDK7 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMedPDB3D3D Structure (crystal)

TargetCyclin-dependent kinase 7(Human)
Carrick Therapeutics

US Patent
LigandPNGBDBM50526797(Ct-7001 | Ct7001 | ICEC-0942 | ICEC0942 | Samuraci...)
Affinity DataIC50:  40nMAssay Description:Inhibition of CDK7 (unknown origin) using YSPTSPSYSPTSPSYSPTSPS peptide as substrate in presence of ATP by luciferase assayMore data for this Ligand-Target Pair
In DepthDetails PubMedPDB3D3D Structure (crystal)

TargetCyclin-dependent kinase 7(Human)
Carrick Therapeutics

US Patent
LigandPNGBDBM50526797(Ct-7001 | Ct7001 | ICEC-0942 | ICEC0942 | Samuraci...)
Affinity DataIC50:  40nMAssay Description:Inhibition of CDK7 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedPDB3D3D Structure (crystal)

TargetCyclin-dependent kinase 7(Human)
Carrick Therapeutics

US Patent
LigandPNGBDBM50526797(Ct-7001 | Ct7001 | ICEC-0942 | ICEC0942 | Samuraci...)
Affinity DataIC50:  40nMAssay Description:Competitive reversible inhibition of CDK7 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedPDB3D3D Structure (crystal)

TargetCyclin-dependent kinase 7(Human)
Carrick Therapeutics

US Patent
LigandPNGBDBM50526797(Ct-7001 | Ct7001 | ICEC-0942 | ICEC0942 | Samuraci...)
Affinity DataIC50:  40nMAssay Description:Inhibition of CDK7 (unknown origin) using N-YSPTSPSYSPTSPSYSPTSPS-C (PolII CTD) peptide as substrate in presence of ATP by luciferase assayMore data for this Ligand-Target Pair
In DepthDetails PubMedPDB3D3D Structure (crystal)

TargetCyclin-dependent kinase 7(Human)
Carrick Therapeutics

US Patent
LigandPNGBDBM50526797(Ct-7001 | Ct7001 | ICEC-0942 | ICEC0942 | Samuraci...)
Affinity DataIC50:  925nMAssay Description:Inhibition of CDK7 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedPDB3D3D Structure (crystal)