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PubMed code 10197969

Compile data set for download or QSAR
Found 5 hits of Enzyme Inhibition Constant Data   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Inositol 1,4,5-trisphosphate receptor


(Homo sapiens)
BDBM50075651
PNG
(1D-myo-inositol 1,3,4,5-tetrakis(dihydrogen phosph...)
Show SMILES O[C@H]1[C@@H](OP(O)(O)=O)[C@H](O)[C@@H](OP(O)(O)=O)[C@H](OP(O)(O)=O)[C@H]1OP(O)(O)=O
Show InChI InChI=1S/C6H16O18P4/c7-1-3(21-25(9,10)11)2(8)5(23-27(15,16)17)6(24-28(18,19)20)4(1)22-26(12,13)14/h1-8H,(H2,9,10,11)(H2,12,13,14)(H2,15,16,17)(H2,18,19,20)/t1-,2-,3-,4+,5-,6-/m0/s1
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Article
PubMed
n/an/a 2.90n/an/an/an/an/an/a



Bergische Universität Wuppertal

Curated by ChEMBL


Assay Description
Inhibition of Ins(1,3,4,5)P4-PtdIns(3,4,5)P3-specific receptor from Pig cerebellum membrane


J Med Chem 42: 1262-73 (1999)


Article DOI: 10.1021/jm981113k
BindingDB Entry DOI: 10.7270/Q2CF9P8S
More data for this
Ligand-Target Pair
Inositol 1,4,5-trisphosphate receptor


(Homo sapiens)
BDBM50075647
PNG
(CHEMBL283791 | Phosphoric acid mono-((1R,2S,3R,4S,...)
Show SMILES O[C@@H]1[C@H](O)[C@H](OP(O)(O)=O)[C@@H](OP(O)(O)=O)[C@H](OP(O)(O)=O)[C@H]1O
Show InChI InChI=1S/C6H15O15P3/c7-1-2(8)4(19-22(10,11)12)6(21-24(16,17)18)5(3(1)9)20-23(13,14)15/h1-9H,(H2,10,11,12)(H2,13,14,15)(H2,16,17,18)/t1-,2-,3-,4+,5-,6-/m0/s1
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Article
PubMed
n/an/a 6.10n/an/an/an/an/an/a



Bergische Universität Wuppertal

Curated by ChEMBL


Assay Description
Inhibition of Ins(1,3,4,5)P4-PtdIns(3,4,5)P3-specific receptor from Pig cerebellum membrane


J Med Chem 42: 1262-73 (1999)


Article DOI: 10.1021/jm981113k
BindingDB Entry DOI: 10.7270/Q2CF9P8S
More data for this
Ligand-Target Pair
Inositol 1,4,5-trisphosphate receptor


(Homo sapiens)
BDBM50075648
PNG
((1R,3S,4R,6R)-4,5,6-trihydroxy-2-methyl-2,3-bis(ph...)
Show SMILES C[C@@]1(OP(O)(O)=O)[C@@H](OP(O)(O)=O)[C@H](O)[C@@H](O)[C@@H](O)[C@H]1OP(O)(O)=O
Show InChI InChI=1S/C7H17O15P3/c1-7(22-25(17,18)19)5(20-23(11,12)13)3(9)2(8)4(10)6(7)21-24(14,15)16/h2-6,8-10H,1H3,(H2,11,12,13)(H2,14,15,16)(H2,17,18,19)/t2-,3-,4-,5+,6-,7-/m1/s1
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Article
PubMed
n/an/a 44n/an/an/an/an/an/a



Bergische Universität Wuppertal

Curated by ChEMBL


Assay Description
Inhibition of Ins(1,3,4,5)P4-PtdIns(3,4,5)P3-specific receptor from Pig cerebellum membrane


J Med Chem 42: 1262-73 (1999)


Article DOI: 10.1021/jm981113k
BindingDB Entry DOI: 10.7270/Q2CF9P8S
More data for this
Ligand-Target Pair
Inositol 1,4,5-trisphosphate receptor


(Homo sapiens)
BDBM50075649
PNG
(1D-myo-inositol 1,4,5,6-tetrakis(dihydrogen phosph...)
Show SMILES O[C@H]1[C@@H](O)[C@@H](OP(O)(O)=O)[C@H](OP(O)(O)=O)[C@@H](OP(O)(O)=O)[C@@H]1OP(O)(O)=O
Show InChI InChI=1S/C6H16O18P4/c7-1-2(8)4(22-26(12,13)14)6(24-28(18,19)20)5(23-27(15,16)17)3(1)21-25(9,10)11/h1-8H,(H2,9,10,11)(H2,12,13,14)(H2,15,16,17)(H2,18,19,20)/t1-,2+,3-,4-,5+,6+/m1/s1
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Article
PubMed
n/an/a 430n/an/an/an/an/an/a



Bergische Universität Wuppertal

Curated by ChEMBL


Assay Description
Inhibition of Ins(1,3,4,5)P4-PtdIns(3,4,5)P3-specific receptor from Pig cerebellum membrane


J Med Chem 42: 1262-73 (1999)


Article DOI: 10.1021/jm981113k
BindingDB Entry DOI: 10.7270/Q2CF9P8S
More data for this
Ligand-Target Pair
Inositol 1,4,5-trisphosphate receptor


(Homo sapiens)
BDBM50075650
PNG
(1D-myo-inositol 3,4,5,6-tetrakisphosphate | 1L-myo...)
Show SMILES O[C@H]1[C@@H](O)[C@H](OP(O)(O)=O)[C@@H](OP(O)(O)=O)[C@H](OP(O)(O)=O)[C@H]1OP(O)(O)=O
Show InChI InChI=1S/C6H16O18P4/c7-1-2(8)4(22-26(12,13)14)6(24-28(18,19)20)5(23-27(15,16)17)3(1)21-25(9,10)11/h1-8H,(H2,9,10,11)(H2,12,13,14)(H2,15,16,17)(H2,18,19,20)/t1-,2+,3-,4-,5+,6+/m0/s1
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KEGG
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Article
PubMed
n/an/a 620n/an/an/an/an/an/a



Bergische Universität Wuppertal

Curated by ChEMBL


Assay Description
Inhibition of Ins(1,3,4,5)P4-PtdIns(3,4,5)P3-specific receptor from Pig cerebellum membrane


J Med Chem 42: 1262-73 (1999)


Article DOI: 10.1021/jm981113k
BindingDB Entry DOI: 10.7270/Q2CF9P8S
More data for this
Ligand-Target Pair
* indicates data uncertainty>20%