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Found 48 Enz. Inhib. hit(s) with all data for entry = 50008726
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50076524(4-Methanesulfonyl-[1,1';2',1'']terphenyl | CHEMBL1...)
Affinity DataIC50:  1.10E+4nMAssay Description:In vitro inhibitory concentration against recombinant human Prostaglandin G/H synthase 2 obtained from baculovirusMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50076514(1-(4'-Methanesulfonyl-biphenyl-2-yl)-piperidine | ...)
Affinity DataIC50:  1.40E+4nMAssay Description:In vitro inhibitory concentration against recombinant human Prostaglandin G/H synthase 2 obtained from baculovirusMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50076535(4-Methanesulfonyl-[1,1';2',1'']terphenyl-4'-ylamin...)
Affinity DataIC50:  1.70E+4nMAssay Description:In vitro inhibitory concentration against ovine COX-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50076532(2-(4'-Methanesulfonyl-biphenyl-2-yl)-6-methoxy-nap...)
Affinity DataIC50:  3.00E+4nMAssay Description:In vitro inhibitory concentration against recombinant human Prostaglandin G/H synthase 2 obtained from baculovirusMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50076519(2-Cyclohexyl-4'-methanesulfonyl-biphenyl | CHEMBL1...)
Affinity DataIC50:  3.10E+4nMAssay Description:In vitro inhibitory concentration against recombinant human Prostaglandin G/H synthase 2 obtained from baculovirusMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50076517(2-Cyclohex-1-enyl-4'-methanesulfonyl-biphenyl | CH...)
Affinity DataIC50:  3.30E+4nMAssay Description:In vitro inhibitory concentration against recombinant human Prostaglandin G/H synthase 2 obtained from baculovirusMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50076520(4'-Methanesulfonyl-2-phenoxy-biphenyl | CHEMBL1723...)
Affinity DataIC50:  3.30E+4nMAssay Description:In vitro inhibitory concentration against recombinant human Prostaglandin G/H synthase 2 obtained from baculovirusMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50076536(4''-Methanesulfonyl-[1,1';2',1'']terphenyl-4'-ylam...)
Affinity DataIC50:  3.50E+4nMAssay Description:In vitro inhibitory concentration against ovine COX-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50076533(4''-Methanesulfonyl-4'-nitro-[1,1';2',1'']terpheny...)
Affinity DataIC50:  3.80E+4nMAssay Description:In vitro inhibitory concentration against recombinant human Prostaglandin G/H synthase 2 obtained from baculovirusMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50072061(3-(4-Methanesulfonyl-phenyl)-2-phenyl-pyridine | C...)
Affinity DataIC50:  3.90E+4nMAssay Description:In vitro inhibitory concentration against recombinant human Prostaglandin G/H synthase 2 obtained from baculovirusMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50076526(2-(4-Methanesulfonyl-phenyl)-3-phenyl-naphthalene ...)
Affinity DataIC50:  4.10E+4nMAssay Description:In vitro inhibitory concentration against recombinant human Prostaglandin G/H synthase 2 obtained from baculovirusMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50076514(1-(4'-Methanesulfonyl-biphenyl-2-yl)-piperidine | ...)
Affinity DataIC50:  4.30E+4nMAssay Description:In vitro inhibitory concentration against ovine COX-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50076518(4-Methanesulfonyl-4'-nitro-[1,1';2',1'']terphenyl ...)
Affinity DataIC50:  4.40E+4nMAssay Description:In vitro inhibitory concentration against recombinant human Prostaglandin G/H synthase 2 obtained from baculovirusMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50076515(4''-Methanesulfonyl-[1,1';2',1'']terphenyl-4'-carb...)
Affinity DataIC50:  4.80E+4nMAssay Description:In vitro inhibitory concentration against recombinant human Prostaglandin G/H synthase 2 obtained from baculovirusMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50076531(2-(4'-Methanesulfonyl-biphenyl-2-yl)-quinoline | C...)
Affinity DataIC50:  5.70E+4nMAssay Description:In vitro inhibitory concentration against recombinant human Prostaglandin G/H synthase 2 obtained from baculovirusMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50076522(3-(4'-Methanesulfonyl-biphenyl-2-yl)-pyridine | CH...)
Affinity DataIC50:  8.70E+4nMAssay Description:In vitro inhibitory concentration against recombinant human Prostaglandin G/H synthase 2 obtained from baculovirusMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50076518(4-Methanesulfonyl-4'-nitro-[1,1';2',1'']terphenyl ...)
Affinity DataIC50: >1.00E+5nMAssay Description:In vitro inhibitory concentration against ovine COX-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50076530(4''-Methanesulfonyl-[1,1';2',1'']terphenyl-4'-ol |...)
Affinity DataIC50:  1.47E+5nMAssay Description:In vitro inhibitory concentration against recombinant human Prostaglandin G/H synthase 2 obtained from baculovirusMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50076536(4''-Methanesulfonyl-[1,1';2',1'']terphenyl-4'-ylam...)
Affinity DataIC50:  1.94E+5nMAssay Description:In vitro inhibitory concentration against recombinant human Prostaglandin G/H synthase 2 obtained from baculovirusMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50076528(4''-Methanesulfonyl-[1,1';2',1'']terphenyl-4'-carb...)
Affinity DataIC50:  2.32E+5nMAssay Description:In vitro inhibitory concentration against ovine COX-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50076535(4-Methanesulfonyl-[1,1';2',1'']terphenyl-4'-ylamin...)
Affinity DataIC50:  2.54E+5nMAssay Description:In vitro inhibitory concentration against recombinant human Prostaglandin G/H synthase 2 obtained from baculovirusMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50076516(4-(4'-Methanesulfonyl-biphenyl-2-yl)-1-methyl-1,2,...)
Affinity DataIC50: >3.00E+5nMAssay Description:In vitro inhibitory concentration against recombinant human Prostaglandin G/H synthase 2 obtained from baculovirusMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50076523(2-(4'-Methanesulfonyl-biphenyl-2-yl)-pyridine | CH...)
Affinity DataIC50: >3.00E+5nMAssay Description:In vitro inhibitory concentration against ovine COX-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50076521(4-(4'-Methanesulfonyl-biphenyl-2-yl)-pyridine | CH...)
Affinity DataIC50: >3.00E+5nMAssay Description:In vitro inhibitory concentration against ovine COX-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50076533(4''-Methanesulfonyl-4'-nitro-[1,1';2',1'']terpheny...)
Affinity DataIC50: >3.00E+5nMAssay Description:In vitro inhibitory concentration against ovine COX-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50076525(2-(4-Methanesulfonyl-phenyl)-3-phenyl-pyridine | C...)
Affinity DataIC50: >3.00E+5nMAssay Description:In vitro inhibitory concentration against ovine COX-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50076534(5-(4'-Methanesulfonyl-biphenyl-2-yl)-pyrimidine | ...)
Affinity DataIC50: >3.00E+5nMAssay Description:In vitro inhibitory concentration against ovine COX-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50076529(2-(4-Methanesulfonyl-phenyl)-3-phenyl-pyrazine | C...)
Affinity DataIC50: >3.00E+5nMAssay Description:In vitro inhibitory concentration against ovine COX-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50076528(4''-Methanesulfonyl-[1,1';2',1'']terphenyl-4'-carb...)
Affinity DataIC50: >3.00E+5nMAssay Description:In vitro inhibitory concentration against recombinant human Prostaglandin G/H synthase 2 obtained from baculovirusMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50076515(4''-Methanesulfonyl-[1,1';2',1'']terphenyl-4'-carb...)
Affinity DataIC50: >3.00E+5nMAssay Description:In vitro inhibitory concentration against ovine COX-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50076529(2-(4-Methanesulfonyl-phenyl)-3-phenyl-pyrazine | C...)
Affinity DataIC50: >3.00E+5nMAssay Description:In vitro inhibitory concentration against recombinant human Prostaglandin G/H synthase 2 obtained from baculovirusMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50076527(2-Benzyl-4'-methanesulfonyl-biphenyl | CHEMBL17431...)
Affinity DataIC50: >3.00E+5nMAssay Description:In vitro inhibitory concentration against ovine COX-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50076534(5-(4'-Methanesulfonyl-biphenyl-2-yl)-pyrimidine | ...)
Affinity DataIC50: >3.00E+5nMAssay Description:In vitro inhibitory concentration against recombinant human Prostaglandin G/H synthase 2 obtained from baculovirusMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50076522(3-(4'-Methanesulfonyl-biphenyl-2-yl)-pyridine | CH...)
Affinity DataIC50: >3.00E+5nMAssay Description:In vitro inhibitory concentration against ovine COX-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50076521(4-(4'-Methanesulfonyl-biphenyl-2-yl)-pyridine | CH...)
Affinity DataIC50: >3.00E+5nMAssay Description:In vitro inhibitory concentration against recombinant human Prostaglandin G/H synthase 2 obtained from baculovirusMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50076523(2-(4'-Methanesulfonyl-biphenyl-2-yl)-pyridine | CH...)
Affinity DataIC50: >3.00E+5nMAssay Description:In vitro inhibitory concentration against recombinant human Prostaglandin G/H synthase 2 obtained from baculovirusMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50076525(2-(4-Methanesulfonyl-phenyl)-3-phenyl-pyridine | C...)
Affinity DataIC50: >3.00E+5nMAssay Description:In vitro inhibitory concentration against recombinant human Prostaglandin G/H synthase 2 obtained from baculovirusMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50076526(2-(4-Methanesulfonyl-phenyl)-3-phenyl-naphthalene ...)
Affinity DataIC50: >3.00E+5nMAssay Description:In vitro inhibitory concentration against ovine COX-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50076527(2-Benzyl-4'-methanesulfonyl-biphenyl | CHEMBL17431...)
Affinity DataIC50: >3.00E+5nMAssay Description:In vitro inhibitory concentration against recombinant human Prostaglandin G/H synthase 2 obtained from baculovirusMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50076516(4-(4'-Methanesulfonyl-biphenyl-2-yl)-1-methyl-1,2,...)
Affinity DataIC50: >3.00E+5nMAssay Description:In vitro inhibitory concentration against ovine COX-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50076530(4''-Methanesulfonyl-[1,1';2',1'']terphenyl-4'-ol |...)
Affinity DataIC50:  4.04E+5nMAssay Description:In vitro inhibitory concentration against ovine COX-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50076531(2-(4'-Methanesulfonyl-biphenyl-2-yl)-quinoline | C...)
Affinity DataIC50: >1.00E+6nMAssay Description:In vitro inhibitory concentration against ovine COX-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50076520(4'-Methanesulfonyl-2-phenoxy-biphenyl | CHEMBL1723...)
Affinity DataIC50: >1.00E+6nMAssay Description:In vitro inhibitory concentration against ovine COX-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50076532(2-(4'-Methanesulfonyl-biphenyl-2-yl)-6-methoxy-nap...)
Affinity DataIC50: >1.00E+6nMAssay Description:In vitro inhibitory concentration against ovine COX-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50076517(2-Cyclohex-1-enyl-4'-methanesulfonyl-biphenyl | CH...)
Affinity DataIC50: >1.00E+6nMAssay Description:In vitro inhibitory concentration against ovine COX-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50072061(3-(4-Methanesulfonyl-phenyl)-2-phenyl-pyridine | C...)
Affinity DataIC50: >1.00E+6nMAssay Description:In vitro inhibitory concentration against ovine COX-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50076524(4-Methanesulfonyl-[1,1';2',1'']terphenyl | CHEMBL1...)
Affinity DataIC50: >1.00E+6nMAssay Description:In vitro inhibitory concentration against ovine COX-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50076519(2-Cyclohexyl-4'-methanesulfonyl-biphenyl | CHEMBL1...)
Affinity DataIC50: >1.00E+6nMAssay Description:In vitro inhibitory concentration against ovine COX-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed