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PubMed code 10340604

Compile data set for download or QSAR
Found 22 hits of Enzyme Inhibition Constant Data   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Prothrombin


(Homo sapiens (Human))
BDBM50076948
PNG
((R)-1-((3R,4R,4aR)-Decahydro-isoquinoline-1-carbon...)
Show SMILES O=C(N[C@@H](CC1CCNCC1)C(=O)C(=O)NCc1ccccc1)[C@H]1CCCN1C(=O)[C@@H]1NCC[C@H]2CCCC[C@@H]12
Show InChI InChI=1S/C31H45N5O4/c37-28(30(39)34-20-22-7-2-1-3-8-22)25(19-21-12-15-32-16-13-21)35-29(38)26-11-6-18-36(26)31(40)27-24-10-5-4-9-23(24)14-17-33-27/h1-3,7-8,21,23-27,32-33H,4-6,9-20H2,(H,34,39)(H,35,38)/t23-,24-,25+,26-,27-/m1/s1
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Curated by ChEMBL


Assay Description
Inhibitory activity against thrombin with respect to Argatroban


Bioorg Med Chem Lett 9: 1227-32 (1999)


Article DOI: 10.1016/s0960-894x(99)00179-1
BindingDB Entry DOI: 10.7270/Q2XW4K9J
More data for this
Ligand-Target Pair
Prothrombin


(Homo sapiens (Human))
BDBM50076945
PNG
((S)-1-((R)-3-Cyclohexyl-2-ethanesulfonylamino-prop...)
Show SMILES CCS(=O)(=O)N[C@H](CC1CCCCC1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CC1CCNCC1)C(=O)c1nccs1
Show InChI InChI=1S/C27H43N5O5S2/c1-2-39(36,37)31-22(18-19-7-4-3-5-8-19)27(35)32-15-6-9-23(32)25(34)30-21(17-20-10-12-28-13-11-20)24(33)26-29-14-16-38-26/h14,16,19-23,28,31H,2-13,15,17-18H2,1H3,(H,30,34)/t21-,22+,23-/m0/s1
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Curated by ChEMBL


Assay Description
Inhibitory activity against thrombin with respect to Argatroban


Bioorg Med Chem Lett 9: 1227-32 (1999)


Article DOI: 10.1016/s0960-894x(99)00179-1
BindingDB Entry DOI: 10.7270/Q2XW4K9J
More data for this
Ligand-Target Pair
Prothrombin


(Homo sapiens (Human))
BDBM50076949
PNG
((S)-1-((R)-3-Cyclohexyl-2-ethanesulfonylamino-prop...)
Show SMILES CCS(=O)(=O)N[C@H](CC1CCCCC1)C(=O)N1CCC[C@H]1C(=O)NC(CC1CCNCC1)C(=O)c1nccs1
Show InChI InChI=1S/C27H43N5O5S2/c1-2-39(36,37)31-22(18-19-7-4-3-5-8-19)27(35)32-15-6-9-23(32)25(34)30-21(17-20-10-12-28-13-11-20)24(33)26-29-14-16-38-26/h14,16,19-23,28,31H,2-13,15,17-18H2,1H3,(H,30,34)/t21?,22-,23+/m1/s1
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Curated by ChEMBL


Assay Description
Inhibitory activity against thrombin with respect to Argatroban


Bioorg Med Chem Lett 9: 1227-32 (1999)


Article DOI: 10.1016/s0960-894x(99)00179-1
BindingDB Entry DOI: 10.7270/Q2XW4K9J
More data for this
Ligand-Target Pair
Prothrombin


(Homo sapiens (Human))
BDBM50076952
PNG
(3-{[(S)-1-((R)-3-Cyclohexyl-2-ethanesulfonylamino-...)
Show SMILES CCS(=O)(=O)N[C@H](CC1CCCCC1)C(=O)N1CCC[C@H]1C(=O)NC(CC1CCNCC1)C(=O)C(O)=O
Show InChI InChI=1S/C25H42N4O7S/c1-2-37(35,36)28-20(16-17-7-4-3-5-8-17)24(32)29-14-6-9-21(29)23(31)27-19(22(30)25(33)34)15-18-10-12-26-13-11-18/h17-21,26,28H,2-16H2,1H3,(H,27,31)(H,33,34)/t19?,20-,21+/m1/s1
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Curated by ChEMBL


Assay Description
Inhibitory activity against thrombin with respect to Argatroban


Bioorg Med Chem Lett 9: 1227-32 (1999)


Article DOI: 10.1016/s0960-894x(99)00179-1
BindingDB Entry DOI: 10.7270/Q2XW4K9J
More data for this
Ligand-Target Pair
Prothrombin


(Homo sapiens (Human))
BDBM50076953
PNG
((R)-1-(3,3-Diphenyl-propionyl)-pyrrolidine-2-carbo...)
Show SMILES O=C(CC(c1ccccc1)c1ccccc1)N1CCC[C@@H]1C(=O)N[C@@H](CC1CCNCC1)C(=O)C(=O)NCc1ccccc1
Show InChI InChI=1S/C36H42N4O4/c41-33(24-30(28-13-6-2-7-14-28)29-15-8-3-9-16-29)40-22-10-17-32(40)35(43)39-31(23-26-18-20-37-21-19-26)34(42)36(44)38-25-27-11-4-1-5-12-27/h1-9,11-16,26,30-32,37H,10,17-25H2,(H,38,44)(H,39,43)/t31-,32+/m0/s1
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Curated by ChEMBL


Assay Description
Inhibitory activity against thrombin with respect to Argatroban


Bioorg Med Chem Lett 9: 1227-32 (1999)


Article DOI: 10.1016/s0960-894x(99)00179-1
BindingDB Entry DOI: 10.7270/Q2XW4K9J
More data for this
Ligand-Target Pair
Coagulation factor X/antithrombin III


(Homo sapiens (human))
BDBM50076951
PNG
(((R)-2-Cyclohexyl-1-{methyl-[(2-oxo-1-piperidin-4-...)
Show SMILES CN(CC(=O)NC(CC1CCNCC1)C(=O)c1nccs1)C(=O)[C@@H](CC1CCCCC1)NCC(O)=O
Show InChI InChI=1S/C25H39N5O5S/c1-30(25(35)20(28-15-22(32)33)14-17-5-3-2-4-6-17)16-21(31)29-19(13-18-7-9-26-10-8-18)23(34)24-27-11-12-36-24/h11-12,17-20,26,28H,2-10,13-16H2,1H3,(H,29,31)(H,32,33)/t19?,20-/m1/s1
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Curated by ChEMBL


Assay Description
Inhibitory activity against Coagulation factor X with respect to Argatroban


Bioorg Med Chem Lett 9: 1227-32 (1999)


Article DOI: 10.1016/s0960-894x(99)00179-1
BindingDB Entry DOI: 10.7270/Q2XW4K9J
More data for this
Ligand-Target Pair
Prothrombin


(Homo sapiens (Human))
BDBM50038001
PNG
((2R,4R)-1-((S)-5-(diaminomethyleneamino)-2-(3-meth...)
Show SMILES C[C@@H]1CCN([C@H](C1)C(O)=O)C(=O)[C@H](CCCNC(N)=N)NS(=O)(=O)c1cccc2CC(C)CNc12
Show InChI InChI=1S/C23H36N6O5S/c1-14-8-10-29(18(12-14)22(31)32)21(30)17(6-4-9-26-23(24)25)28-35(33,34)19-7-3-5-16-11-15(2)13-27-20(16)19/h3,5,7,14-15,17-18,27-28H,4,6,8-13H2,1-2H3,(H,31,32)(H4,24,25,26)/t14-,15?,17+,18-/m1/s1
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Curated by ChEMBL


Assay Description
Inhibitory activity against thrombin


Bioorg Med Chem Lett 9: 1227-32 (1999)


Article DOI: 10.1016/s0960-894x(99)00179-1
BindingDB Entry DOI: 10.7270/Q2XW4K9J
More data for this
Ligand-Target Pair
Prothrombin


(Homo sapiens (Human))
BDBM50076946
PNG
((S)-N-Benzyl-2-oxo-3-[2-(2-oxo-3-phenylmethanesulf...)
Show SMILES O=C(Cn1cccc(NS(=O)(=O)Cc2ccccc2)c1=O)N[C@@H](CC1CCNCC1)C(=O)C(=O)NCc1ccccc1
Show InChI InChI=1S/C30H35N5O6S/c36-27(20-35-17-7-12-25(30(35)39)34-42(40,41)21-24-10-5-2-6-11-24)33-26(18-22-13-15-31-16-14-22)28(37)29(38)32-19-23-8-3-1-4-9-23/h1-12,17,22,26,31,34H,13-16,18-21H2,(H,32,38)(H,33,36)/t26-/m0/s1
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Curated by ChEMBL


Assay Description
Inhibitory activity against thrombin with respect to Argatroban


Bioorg Med Chem Lett 9: 1227-32 (1999)


Article DOI: 10.1016/s0960-894x(99)00179-1
BindingDB Entry DOI: 10.7270/Q2XW4K9J
More data for this
Ligand-Target Pair
Coagulation factor X/antithrombin III


(Homo sapiens (human))
BDBM50076954
PNG
(((R)-2-Cyclohexyl-1-{[(2-oxo-1-piperidin-4-ylmethy...)
Show SMILES OC(=O)CN[C@H](CC1CCCCC1)C(=O)NCC(=O)NC(CC1CCNCC1)C(=O)c1nccs1
Show InChI InChI=1S/C24H37N5O5S/c30-20(14-28-23(34)19(27-15-21(31)32)13-16-4-2-1-3-5-16)29-18(12-17-6-8-25-9-7-17)22(33)24-26-10-11-35-24/h10-11,16-19,25,27H,1-9,12-15H2,(H,28,34)(H,29,30)(H,31,32)/t18?,19-/m1/s1
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Research and Development

Curated by ChEMBL


Assay Description
Inhibitory activity against Coagulation factor X with respect to Argatroban


Bioorg Med Chem Lett 9: 1227-32 (1999)


Article DOI: 10.1016/s0960-894x(99)00179-1
BindingDB Entry DOI: 10.7270/Q2XW4K9J
More data for this
Ligand-Target Pair
Prothrombin


(Homo sapiens (Human))
BDBM50076947
PNG
((S)-N-Benzyl-2-oxo-3-[2-(2-oxo-3-phenylmethanesulf...)
Show SMILES O=C(CN1CCCCC(NS(=O)(=O)Cc2ccccc2)C1=O)N[C@@H](CC1CCNCC1)C(=O)C(=O)NCc1ccccc1
Show InChI InChI=1S/C31H41N5O6S/c37-28(21-36-18-8-7-13-26(31(36)40)35-43(41,42)22-25-11-5-2-6-12-25)34-27(19-23-14-16-32-17-15-23)29(38)30(39)33-20-24-9-3-1-4-10-24/h1-6,9-12,23,26-27,32,35H,7-8,13-22H2,(H,33,39)(H,34,37)/t26?,27-/m0/s1
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Curated by ChEMBL


Assay Description
Inhibitory activity against thrombin with respect to Argatroban


Bioorg Med Chem Lett 9: 1227-32 (1999)


Article DOI: 10.1016/s0960-894x(99)00179-1
BindingDB Entry DOI: 10.7270/Q2XW4K9J
More data for this
Ligand-Target Pair
Coagulation factor X/antithrombin III


(Homo sapiens (human))
BDBM50076945
PNG
((S)-1-((R)-3-Cyclohexyl-2-ethanesulfonylamino-prop...)
Show SMILES CCS(=O)(=O)N[C@H](CC1CCCCC1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CC1CCNCC1)C(=O)c1nccs1
Show InChI InChI=1S/C27H43N5O5S2/c1-2-39(36,37)31-22(18-19-7-4-3-5-8-19)27(35)32-15-6-9-23(32)25(34)30-21(17-20-10-12-28-13-11-20)24(33)26-29-14-16-38-26/h14,16,19-23,28,31H,2-13,15,17-18H2,1H3,(H,30,34)/t21-,22+,23-/m0/s1
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Research and Development

Curated by ChEMBL


Assay Description
Inhibitory activity against Coagulation factor X with respect to Argatroban


Bioorg Med Chem Lett 9: 1227-32 (1999)


Article DOI: 10.1016/s0960-894x(99)00179-1
BindingDB Entry DOI: 10.7270/Q2XW4K9J
More data for this
Ligand-Target Pair
Coagulation factor X/antithrombin III


(Homo sapiens (human))
BDBM50076948
PNG
((R)-1-((3R,4R,4aR)-Decahydro-isoquinoline-1-carbon...)
Show SMILES O=C(N[C@@H](CC1CCNCC1)C(=O)C(=O)NCc1ccccc1)[C@H]1CCCN1C(=O)[C@@H]1NCC[C@H]2CCCC[C@@H]12
Show InChI InChI=1S/C31H45N5O4/c37-28(30(39)34-20-22-7-2-1-3-8-22)25(19-21-12-15-32-16-13-21)35-29(38)26-11-6-18-36(26)31(40)27-24-10-5-4-9-23(24)14-17-33-27/h1-3,7-8,21,23-27,32-33H,4-6,9-20H2,(H,34,39)(H,35,38)/t23-,24-,25+,26-,27-/m1/s1
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Curated by ChEMBL


Assay Description
Inhibitory activity against Coagulation factor X with respect to Argatroban


Bioorg Med Chem Lett 9: 1227-32 (1999)


Article DOI: 10.1016/s0960-894x(99)00179-1
BindingDB Entry DOI: 10.7270/Q2XW4K9J
More data for this
Ligand-Target Pair
Prothrombin


(Homo sapiens (Human))
BDBM50076950
PNG
(CHEMBL284008 | {(R)-2-Cyclohexyl-1-[(S)-1-(2-oxo-1...)
Show SMILES OC(=O)CN[C@H](CC1CCCCC1)C(=O)N[C@@H](Cc1ccccc1)C(=O)NC(CC1CCNCC1)C(=O)c1nccs1
Show InChI InChI=1S/C31H43N5O5S/c37-27(38)20-34-25(18-21-7-3-1-4-8-21)29(40)36-26(19-22-9-5-2-6-10-22)30(41)35-24(17-23-11-13-32-14-12-23)28(39)31-33-15-16-42-31/h2,5-6,9-10,15-16,21,23-26,32,34H,1,3-4,7-8,11-14,17-20H2,(H,35,41)(H,36,40)(H,37,38)/t24?,25-,26+/m1/s1
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Curated by ChEMBL


Assay Description
Inhibitory activity against thrombin with respect to Argatroban


Bioorg Med Chem Lett 9: 1227-32 (1999)


Article DOI: 10.1016/s0960-894x(99)00179-1
BindingDB Entry DOI: 10.7270/Q2XW4K9J
More data for this
Ligand-Target Pair
Coagulation factor X/antithrombin III


(Homo sapiens (human))
BDBM50076946
PNG
((S)-N-Benzyl-2-oxo-3-[2-(2-oxo-3-phenylmethanesulf...)
Show SMILES O=C(Cn1cccc(NS(=O)(=O)Cc2ccccc2)c1=O)N[C@@H](CC1CCNCC1)C(=O)C(=O)NCc1ccccc1
Show InChI InChI=1S/C30H35N5O6S/c36-27(20-35-17-7-12-25(30(35)39)34-42(40,41)21-24-10-5-2-6-11-24)33-26(18-22-13-15-31-16-14-22)28(37)29(38)32-19-23-8-3-1-4-9-23/h1-12,17,22,26,31,34H,13-16,18-21H2,(H,32,38)(H,33,36)/t26-/m0/s1
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Research and Development

Curated by ChEMBL


Assay Description
Inhibitory activity against Coagulation factor X with respect to Argatroban


Bioorg Med Chem Lett 9: 1227-32 (1999)


Article DOI: 10.1016/s0960-894x(99)00179-1
BindingDB Entry DOI: 10.7270/Q2XW4K9J
More data for this
Ligand-Target Pair
Coagulation factor X/antithrombin III


(Homo sapiens (human))
BDBM50076949
PNG
((S)-1-((R)-3-Cyclohexyl-2-ethanesulfonylamino-prop...)
Show SMILES CCS(=O)(=O)N[C@H](CC1CCCCC1)C(=O)N1CCC[C@H]1C(=O)NC(CC1CCNCC1)C(=O)c1nccs1
Show InChI InChI=1S/C27H43N5O5S2/c1-2-39(36,37)31-22(18-19-7-4-3-5-8-19)27(35)32-15-6-9-23(32)25(34)30-21(17-20-10-12-28-13-11-20)24(33)26-29-14-16-38-26/h14,16,19-23,28,31H,2-13,15,17-18H2,1H3,(H,30,34)/t21?,22-,23+/m1/s1
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Curated by ChEMBL


Assay Description
Inhibitory activity against Coagulation factor X with respect to Argatroban


Bioorg Med Chem Lett 9: 1227-32 (1999)


Article DOI: 10.1016/s0960-894x(99)00179-1
BindingDB Entry DOI: 10.7270/Q2XW4K9J
More data for this
Ligand-Target Pair
Prothrombin


(Homo sapiens (Human))
BDBM50076951
PNG
(((R)-2-Cyclohexyl-1-{methyl-[(2-oxo-1-piperidin-4-...)
Show SMILES CN(CC(=O)NC(CC1CCNCC1)C(=O)c1nccs1)C(=O)[C@@H](CC1CCCCC1)NCC(O)=O
Show InChI InChI=1S/C25H39N5O5S/c1-30(25(35)20(28-15-22(32)33)14-17-5-3-2-4-6-17)16-21(31)29-19(13-18-7-9-26-10-8-18)23(34)24-27-11-12-36-24/h11-12,17-20,26,28H,2-10,13-16H2,1H3,(H,29,31)(H,32,33)/t19?,20-/m1/s1
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Research and Development

Curated by ChEMBL


Assay Description
Inhibitory activity against thrombin with respect to Argatroban


Bioorg Med Chem Lett 9: 1227-32 (1999)


Article DOI: 10.1016/s0960-894x(99)00179-1
BindingDB Entry DOI: 10.7270/Q2XW4K9J
More data for this
Ligand-Target Pair
Coagulation factor X/antithrombin III


(Homo sapiens (human))
BDBM50076947
PNG
((S)-N-Benzyl-2-oxo-3-[2-(2-oxo-3-phenylmethanesulf...)
Show SMILES O=C(CN1CCCCC(NS(=O)(=O)Cc2ccccc2)C1=O)N[C@@H](CC1CCNCC1)C(=O)C(=O)NCc1ccccc1
Show InChI InChI=1S/C31H41N5O6S/c37-28(21-36-18-8-7-13-26(31(36)40)35-43(41,42)22-25-11-5-2-6-12-25)34-27(19-23-14-16-32-17-15-23)29(38)30(39)33-20-24-9-3-1-4-10-24/h1-6,9-12,23,26-27,32,35H,7-8,13-22H2,(H,33,39)(H,34,37)/t26?,27-/m0/s1
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n/an/a 5.20E+3n/an/an/an/an/an/a



Research and Development

Curated by ChEMBL


Assay Description
Inhibitory activity against Coagulation factor X with respect to Argatroban


Bioorg Med Chem Lett 9: 1227-32 (1999)


Article DOI: 10.1016/s0960-894x(99)00179-1
BindingDB Entry DOI: 10.7270/Q2XW4K9J
More data for this
Ligand-Target Pair
Coagulation factor X/antithrombin III


(Homo sapiens (human))
BDBM50076950
PNG
(CHEMBL284008 | {(R)-2-Cyclohexyl-1-[(S)-1-(2-oxo-1...)
Show SMILES OC(=O)CN[C@H](CC1CCCCC1)C(=O)N[C@@H](Cc1ccccc1)C(=O)NC(CC1CCNCC1)C(=O)c1nccs1
Show InChI InChI=1S/C31H43N5O5S/c37-27(38)20-34-25(18-21-7-3-1-4-8-21)29(40)36-26(19-22-9-5-2-6-10-22)30(41)35-24(17-23-11-13-32-14-12-23)28(39)31-33-15-16-42-31/h2,5-6,9-10,15-16,21,23-26,32,34H,1,3-4,7-8,11-14,17-20H2,(H,35,41)(H,36,40)(H,37,38)/t24?,25-,26+/m1/s1
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n/an/a 7.80E+3n/an/an/an/an/an/a



Research and Development

Curated by ChEMBL


Assay Description
Inhibitory activity against Coagulation factor X with respect to Argatroban


Bioorg Med Chem Lett 9: 1227-32 (1999)


Article DOI: 10.1016/s0960-894x(99)00179-1
BindingDB Entry DOI: 10.7270/Q2XW4K9J
More data for this
Ligand-Target Pair
Coagulation factor X/antithrombin III


(Homo sapiens (human))
BDBM50076952
PNG
(3-{[(S)-1-((R)-3-Cyclohexyl-2-ethanesulfonylamino-...)
Show SMILES CCS(=O)(=O)N[C@H](CC1CCCCC1)C(=O)N1CCC[C@H]1C(=O)NC(CC1CCNCC1)C(=O)C(O)=O
Show InChI InChI=1S/C25H42N4O7S/c1-2-37(35,36)28-20(16-17-7-4-3-5-8-17)24(32)29-14-6-9-21(29)23(31)27-19(22(30)25(33)34)15-18-10-12-26-13-11-18/h17-21,26,28H,2-16H2,1H3,(H,27,31)(H,33,34)/t19?,20-,21+/m1/s1
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n/an/a 1.60E+4n/an/an/an/an/an/a



Research and Development

Curated by ChEMBL


Assay Description
Inhibitory activity against Coagulation factor X with respect to Argatroban


Bioorg Med Chem Lett 9: 1227-32 (1999)


Article DOI: 10.1016/s0960-894x(99)00179-1
BindingDB Entry DOI: 10.7270/Q2XW4K9J
More data for this
Ligand-Target Pair
Prothrombin


(Homo sapiens (Human))
BDBM50076954
PNG
(((R)-2-Cyclohexyl-1-{[(2-oxo-1-piperidin-4-ylmethy...)
Show SMILES OC(=O)CN[C@H](CC1CCCCC1)C(=O)NCC(=O)NC(CC1CCNCC1)C(=O)c1nccs1
Show InChI InChI=1S/C24H37N5O5S/c30-20(14-28-23(34)19(27-15-21(31)32)13-16-4-2-1-3-5-16)29-18(12-17-6-8-25-9-7-17)22(33)24-26-10-11-35-24/h10-11,16-19,25,27H,1-9,12-15H2,(H,28,34)(H,29,30)(H,31,32)/t18?,19-/m1/s1
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n/an/a 1.94E+4n/an/an/an/an/an/a



Research and Development

Curated by ChEMBL


Assay Description
Inhibitory activity against thrombin with respect to Argatroban


Bioorg Med Chem Lett 9: 1227-32 (1999)


Article DOI: 10.1016/s0960-894x(99)00179-1
BindingDB Entry DOI: 10.7270/Q2XW4K9J
More data for this
Ligand-Target Pair
Coagulation factor X/antithrombin III


(Homo sapiens (human))
BDBM50076953
PNG
((R)-1-(3,3-Diphenyl-propionyl)-pyrrolidine-2-carbo...)
Show SMILES O=C(CC(c1ccccc1)c1ccccc1)N1CCC[C@@H]1C(=O)N[C@@H](CC1CCNCC1)C(=O)C(=O)NCc1ccccc1
Show InChI InChI=1S/C36H42N4O4/c41-33(24-30(28-13-6-2-7-14-28)29-15-8-3-9-16-29)40-22-10-17-32(40)35(43)39-31(23-26-18-20-37-21-19-26)34(42)36(44)38-25-27-11-4-1-5-12-27/h1-9,11-16,26,30-32,37H,10,17-25H2,(H,38,44)(H,39,43)/t31-,32+/m0/s1
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n/an/a 5.40E+4n/an/an/an/an/an/a



Research and Development

Curated by ChEMBL


Assay Description
Inhibitory activity against Coagulation factor X with respect to Argatroban


Bioorg Med Chem Lett 9: 1227-32 (1999)


Article DOI: 10.1016/s0960-894x(99)00179-1
BindingDB Entry DOI: 10.7270/Q2XW4K9J
More data for this
Ligand-Target Pair
Coagulation factor X/antithrombin III


(Homo sapiens (human))
BDBM50038001
PNG
((2R,4R)-1-((S)-5-(diaminomethyleneamino)-2-(3-meth...)
Show SMILES C[C@@H]1CCN([C@H](C1)C(O)=O)C(=O)[C@H](CCCNC(N)=N)NS(=O)(=O)c1cccc2CC(C)CNc12
Show InChI InChI=1S/C23H36N6O5S/c1-14-8-10-29(18(12-14)22(31)32)21(30)17(6-4-9-26-23(24)25)28-35(33,34)19-7-3-5-16-11-15(2)13-27-20(16)19/h3,5,7,14-15,17-18,27-28H,4,6,8-13H2,1-2H3,(H,31,32)(H4,24,25,26)/t14-,15?,17+,18-/m1/s1
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Article
PubMed
n/an/a 1.34E+5n/an/an/an/an/an/a



Research and Development

Curated by ChEMBL


Assay Description
Inhibitory activity against Coagulation factor X


Bioorg Med Chem Lett 9: 1227-32 (1999)


Article DOI: 10.1016/s0960-894x(99)00179-1
BindingDB Entry DOI: 10.7270/Q2XW4K9J
More data for this
Ligand-Target Pair
* indicates data uncertainty>20%