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PubMed code 10360750

Compile data set for download or QSAR
Found 2 hits of Enzyme Inhibition Constant Data   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Phospholipase C-gamma-1


(Homo sapiens)
BDBM50077775
PNG
((4aS,6aR,6bR,10S,12aR,14bS)-10-Hydroxy-6a-[(E)-3-(...)
Show SMILES COc1cc(\C=C\C(=O)OC[C@@]23CC[C@]4(CCC(C)(C)C[C@H]4C2=CCC2[C@@]4(C)CC[C@H](O)C(C)(C)C4CC[C@@]32C)C(O)=O)ccc1O
Show InChI InChI=1S/C40H56O7/c1-35(2)18-19-39(34(44)45)20-21-40(24-47-33(43)13-9-25-8-11-28(41)29(22-25)46-7)26(27(39)23-35)10-12-31-37(5)16-15-32(42)36(3,4)30(37)14-17-38(31,40)6/h8-11,13,22,27,30-32,41-42H,12,14-21,23-24H2,1-7H3,(H,44,45)/b13-9+/t27-,30?,31?,32-,37-,38+,39-,40-/m0/s1
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PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 3.57E+4n/an/an/an/an/an/a



Seoul National University

Curated by ChEMBL


Assay Description
Inhibitory concentration of the compound was evaluated against phospholipase C-gamma1


Bioorg Med Chem Lett 9: 1429-32 (1999)


Article DOI: 10.1016/s0960-894x(99)00211-5
BindingDB Entry DOI: 10.7270/Q2MG7NQZ
More data for this
Ligand-Target Pair
Phospholipase C-gamma-1


(Homo sapiens)
BDBM50077774
PNG
((4aS,6aR,6bR,10S,12aR,14bS)-10-Hydroxy-6a-[(Z)-3-(...)
Show SMILES COc1cc(\C=C/C(=O)OC[C@@]23CC[C@]4(CCC(C)(C)C[C@H]4C2=CCC2[C@@]4(C)CC[C@H](O)C(C)(C)C4CC[C@@]32C)C(O)=O)ccc1O
Show InChI InChI=1S/C40H56O7/c1-35(2)18-19-39(34(44)45)20-21-40(24-47-33(43)13-9-25-8-11-28(41)29(22-25)46-7)26(27(39)23-35)10-12-31-37(5)16-15-32(42)36(3,4)30(37)14-17-38(31,40)6/h8-11,13,22,27,30-32,41-42H,12,14-21,23-24H2,1-7H3,(H,44,45)/b13-9-/t27-,30?,31?,32-,37-,38+,39-,40-/m0/s1
PDB
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NCI pathway
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UniProtKB/SwissProt

B.MOAD
GoogleScholar
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CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 4.46E+4n/an/an/an/an/an/a



Seoul National University

Curated by ChEMBL


Assay Description
Inhibitory concentration of the compound was evaluated against phospholipase C-gamma1


Bioorg Med Chem Lett 9: 1429-32 (1999)


Article DOI: 10.1016/s0960-894x(99)00211-5
BindingDB Entry DOI: 10.7270/Q2MG7NQZ
More data for this
Ligand-Target Pair
* indicates data uncertainty>20%