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Found 22 Enz. Inhib. hit(s) with all data for entry = 50009067
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50079859((R)-2-[2,6-Dibromo-4-(6-bromo-benzo[b]naphtho[2,3-...)
Affinity DataIC50:  11nMAssay Description:The compound was tested in vitro for the inhibitory activity against Protein-tyrosine phosphatase 1B (human PTPases.)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50079857((R)-2-[2,6-Dibromo-4-(6-bromo-benzo[b]naphtho[2,3-...)
Affinity DataIC50:  61nMAssay Description:The compound was tested in vitro for the inhibitory activity against Protein-tyrosine phosphatase 1B (human PTPases.)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50079855((R)-2-[2,6-Dibromo-4-(6-bromo-benzo[b]naphtho[2,3-...)
Affinity DataIC50:  80nMAssay Description:The compound was tested in vitro for the inhibitory activity against hPTP1B (human PTPases.)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50079855((R)-2-[2,6-Dibromo-4-(6-bromo-benzo[b]naphtho[2,3-...)
Affinity DataIC50:  83nMAssay Description:The compound was tested in vitro for the inhibitory activity against Protein-tyrosine phosphatase 1B (human PTPases.)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50079858(CHEMBL322061 | [2,6-Dibromo-4-(6-bromo-benzo[b]nap...)
Affinity DataIC50:  145nMAssay Description:The compound was tested in vitro for the inhibitory activity against Protein-tyrosine phosphatase 1B (human PTPases.)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50079860(2,6-Dibromo-4-(6-bromo-benzo[b]naphtho[2,3-d]thiop...)
Affinity DataIC50:  384nMAssay Description:The compound was tested in vitro for the inhibitory activity against Protein-tyrosine phosphatase 1B (human PTPases.)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50079856(CHEMBL108721 | [2,6-Dibromo-4-(6-bromo-benzo[b]nap...)
Affinity DataIC50:  386nMAssay Description:The compound was tested in vitro for the inhibitory activity against Protein-tyrosine phosphatase 1B (human PTPases.)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50079856(CHEMBL108721 | [2,6-Dibromo-4-(6-bromo-benzo[b]nap...)
Affinity DataIC50:  390nMAssay Description:The compound was tested in vitro for the inhibitory activity against Protein-tyrosine phosphatase 1B (human PTPases.)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein phosphatase F(Homo sapiens (Human))
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50079855((R)-2-[2,6-Dibromo-4-(6-bromo-benzo[b]naphtho[2,3-...)
Affinity DataIC50:  420nMAssay Description:The compound was tested in vitro for the inhibitory activity against LAR (human Protein-tyrosine phosphatase F)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein phosphatase beta(Homo sapiens (Human))
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50079855((R)-2-[2,6-Dibromo-4-(6-bromo-benzo[b]naphtho[2,3-...)
Affinity DataIC50:  500nMAssay Description:The compound was tested in vitro for the inhibitory activity against Protein-tyrosine phosphatase beta (SH-PTP1) (human PTPases.)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein phosphatase beta(Homo sapiens (Human))
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50079856(CHEMBL108721 | [2,6-Dibromo-4-(6-bromo-benzo[b]nap...)
Affinity DataIC50:  600nMAssay Description:The compound was tested in vitro for the inhibitory activity against Protein-tyrosine phosphatase beta (SH-PTP1) (human PTPases.)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein phosphatase F(Homo sapiens (Human))
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50079856(CHEMBL108721 | [2,6-Dibromo-4-(6-bromo-benzo[b]nap...)
Affinity DataIC50:  1.50E+3nMAssay Description:The compound was tested in vitro for the inhibitory activity against LAR (human Protein-tyrosine phosphatase F)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 12(Homo sapiens (Human))
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50079855((R)-2-[2,6-Dibromo-4-(6-bromo-benzo[b]naphtho[2,3-...)
Affinity DataIC50:  2.20E+3nMAssay Description:The compound was tested in vitro for the inhibitory activity against Protein tyrosine phosphatase PEST (SH-PTP1) (human PTPases.)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 12(Homo sapiens (Human))
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50079856(CHEMBL108721 | [2,6-Dibromo-4-(6-bromo-benzo[b]nap...)
Affinity DataIC50:  2.30E+3nMAssay Description:The compound was tested in vitro for the inhibitory activity against Protein tyrosine phosphatase PEST (SH-PTP1) (human PTPases.)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 6(Homo sapiens (Human))
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50079856(CHEMBL108721 | [2,6-Dibromo-4-(6-bromo-benzo[b]nap...)
Affinity DataIC50:  5.00E+3nMAssay Description:The compound was tested in vitro for the inhibitory activity against Protein-tyrosine phosphatase 1C (SH-PTP1) (human PTPases.)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein phosphatase C(Homo sapiens (Human))
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50079855((R)-2-[2,6-Dibromo-4-(6-bromo-benzo[b]naphtho[2,3-...)
Affinity DataIC50:  6.30E+3nMAssay Description:The compound was tested in vitro for the inhibitory activity against CD45 antigen (human PTPases.)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity protein phosphatase 3(Homo sapiens (Human))
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50079856(CHEMBL108721 | [2,6-Dibromo-4-(6-bromo-benzo[b]nap...)
Affinity DataIC50:  7.90E+3nMAssay Description:The compound was tested in vitro for the inhibitory activity against Dual specificity protein phosphatase 3 (SH-PTP1) (human PTPases.)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 6(Homo sapiens (Human))
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50079855((R)-2-[2,6-Dibromo-4-(6-bromo-benzo[b]naphtho[2,3-...)
Affinity DataIC50:  9.00E+3nMAssay Description:The compound was tested in vitro for the inhibitory activity against Protein-tyrosine phosphatase 1C (SH-PTP1) (human PTPases.)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein phosphatase C(Homo sapiens (Human))
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50079856(CHEMBL108721 | [2,6-Dibromo-4-(6-bromo-benzo[b]nap...)
Affinity DataIC50:  9.10E+3nMAssay Description:The compound was tested in vitro for the inhibitory activity against CD45 antigen (human PTPases.)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity protein phosphatase 3(Homo sapiens (Human))
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50079855((R)-2-[2,6-Dibromo-4-(6-bromo-benzo[b]naphtho[2,3-...)
Affinity DataIC50:  1.10E+4nMAssay Description:The compound was tested in vitro for the inhibitory activity against Dual specificity protein phosphatase 3 (SH-PTP1) (human PTPases.)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein phosphatase alpha(Homo sapiens (Human))
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50079855((R)-2-[2,6-Dibromo-4-(6-bromo-benzo[b]naphtho[2,3-...)
Affinity DataIC50:  1.30E+4nMAssay Description:The compound was tested in vitro for the inhibitory activity against Protein-tyrosine phosphatase 1 alpha (LRP) (human PTPases.)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein phosphatase alpha(Homo sapiens (Human))
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50079856(CHEMBL108721 | [2,6-Dibromo-4-(6-bromo-benzo[b]nap...)
Affinity DataIC50:  1.70E+4nMAssay Description:The compound was tested in vitro for the inhibitory activity against Protein-tyrosine phosphatase 1 alpha (LRP) (human PTPases.)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed