Compile Data Set for Download or QSAR
maximum 50k data
Found 8 Enz. Inhib. hit(s) with all data for entry = 50009594
TargetIleal sodium/bile acid cotransporter(Homo sapiens (Human))
Searle Discovery

Curated by ChEMBL
LigandPNGBDBM50085476(1-(3,4-Dimethoxy-phenyl)-3-(3-ethyl-pentanoyl)-4-h...)
Affinity DataIC50:  2.55E+3nMAssay Description:In vitro for inhibition of [14C]-taurocholate uptake in baby hamster kidney cells transfected with the cDNA of human Bile acid transporter (H14 cells...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIleal sodium/bile acid cotransporter(Homo sapiens (Human))
Searle Discovery

Curated by ChEMBL
LigandPNGBDBM50085479(4-(3,4-Dimethoxy-phenyl)-5,6,7-trimethoxy-3-methyl...)
Affinity DataIC50:  3.50E+3nMAssay Description:In vitro for inhibition of [14C]-taurocholate uptake in baby hamster kidney cells transfected with the cDNA of human Bile acid transporter (H14 cells...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIleal sodium/bile acid cotransporter(Homo sapiens (Human))
Searle Discovery

Curated by ChEMBL
LigandPNGBDBM50085473(4-(3,4-Dimethoxy-phenyl)-2-isopropyl-5,6,7-trimeth...)
Affinity DataIC50:  4.40E+3nMAssay Description:In vitro for inhibition of [14C]-taurocholate uptake in baby hamster kidney cells transfected with the cDNA of human Bile acid transporter (H14 cells...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIleal sodium/bile acid cotransporter(Homo sapiens (Human))
Searle Discovery

Curated by ChEMBL
LigandPNGBDBM50085474(4-(3,4-Dimethoxy-phenyl)-2-ethyl-5,6,7-trimethoxy-...)
Affinity DataIC50:  7.10E+3nMAssay Description:In vitro for inhibition of [14C]-taurocholate uptake in baby hamster kidney cells transfected with the cDNA of human Bile acid transporter (H14 cells...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIleal sodium/bile acid cotransporter(Homo sapiens (Human))
Searle Discovery

Curated by ChEMBL
LigandPNGBDBM50085477(4-(3,4-Dimethoxy-phenyl)-5,6,7-trimethoxy-2-(3-met...)
Affinity DataIC50:  9.20E+3nMAssay Description:In vitro for inhibition of [14C]-taurocholate uptake in baby hamster kidney cells transfected with the cDNA of human Bile acid transporter (H14 cells...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIleal sodium/bile acid cotransporter(Homo sapiens (Human))
Searle Discovery

Curated by ChEMBL
LigandPNGBDBM50085478(4-(3,4-Dimethoxy-phenyl)-2-isopropyl-5,6,7-trimeth...)
Affinity DataIC50:  1.08E+4nMAssay Description:In vitro for inhibition of [14C]-taurocholate uptake in baby hamster kidney cells transfected with the cDNA of human Bile acid transporter (H14 cells...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIleal sodium/bile acid cotransporter(Homo sapiens (Human))
Searle Discovery

Curated by ChEMBL
LigandPNGBDBM50085480(4-(3,4-Dimethoxy-phenyl)-2-(3-ethyl-pentyl)-5,6,7-...)
Affinity DataIC50:  1.33E+4nMAssay Description:In vitro for inhibition of [14C]-taurocholate uptake in baby hamster kidney cells transfected with the cDNA of human Bile acid transporter (H14 cells...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIleal sodium/bile acid cotransporter(Homo sapiens (Human))
Searle Discovery

Curated by ChEMBL
LigandPNGBDBM50085475(4-(3,4-Dimethoxy-phenyl)-2-(4-fluoro-phenyl)-5,6,7...)
Affinity DataIC50:  4.90E+4nMAssay Description:In vitro for inhibition of [14C]-taurocholate uptake in baby hamster kidney cells transfected with the cDNA of human Bile acid transporter (H14 cells...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed