Compile Data Set for Download or QSAR
maximum 50k data
Found 11 Enz. Inhib. hit(s) with all data for entry = 50009906
TargetIntegrin alpha-4(Homo sapiens (Human))
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50089019((8R,13R)-13-[(S)-2-Amino-3-(4-hydroxy-phenyl)-prop...)
Affinity DataIC50:  0.5nMAssay Description:Inhibition of VLA-4 binding to recombinant human VCAM using Solid phase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4(Homo sapiens (Human))
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50089029((8R,13R)-13-[(S)-2-Acetylamino-3-(4-hydroxy-phenyl...)
Affinity DataIC50:  0.700nMAssay Description:Inhibition of VLA-4 binding to recombinant human VCAM using Solid phase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4(Homo sapiens (Human))
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50089027((5R,8S,13S,15aR)-8-[(S)-2-Acetylamino-3-(4-hydroxy...)
Affinity DataIC50:  1.80nMAssay Description:Inhibition of VLA-4 binding to recombinant human VCAM using Solid phase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4(Homo sapiens (Human))
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50089030((4R,12R)-12-[(S)-2-Amino-3-(4-hydroxy-phenyl)-prop...)
Affinity DataIC50:  3.90nMAssay Description:Inhibition of VLA-4 binding to recombinant human VCAM using Solid phase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4(Homo sapiens (Human))
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50089026((8R,13R)-13-[(S)-2-Amino-3-(4-hydroxy-phenyl)-prop...)
Affinity DataIC50:  5nMAssay Description:Inhibition of VLA-4 binding to recombinant human VCAM using Solid phase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4(Homo sapiens (Human))
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50089029((8R,13R)-13-[(S)-2-Acetylamino-3-(4-hydroxy-phenyl...)
Affinity DataIC50:  12nMAssay Description:Inhibition of VLA-4 binding to recombinant human VCAM using Ramos cell assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4(Homo sapiens (Human))
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50089025((8R,13R)-13-[(S)-2-Amino-3-(4-hydroxy-phenyl)-prop...)
Affinity DataIC50:  19nMAssay Description:Inhibition of VLA-4 binding to recombinant human VCAM using Ramos cell assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4(Homo sapiens (Human))
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50089019((8R,13R)-13-[(S)-2-Amino-3-(4-hydroxy-phenyl)-prop...)
Affinity DataIC50:  24nMAssay Description:Inhibition of VLA-4 binding to recombinant human VCAM using Solid phase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4(Homo sapiens (Human))
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50089028((4R,12R)-12-[(S)-2-Amino-3-(4-hydroxy-phenyl)-prop...)
Affinity DataIC50:  112nMAssay Description:Inhibition of VLA-4 binding to recombinant human VCAM using Solid phase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4(Homo sapiens (Human))
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50089027((5R,8S,13S,15aR)-8-[(S)-2-Acetylamino-3-(4-hydroxy...)
Affinity DataIC50:  200nMAssay Description:Inhibition of VLA-4 binding to recombinant human VCAM using Ramos cell assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4(Homo sapiens (Human))
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50089025((8R,13R)-13-[(S)-2-Amino-3-(4-hydroxy-phenyl)-prop...)
Affinity DataIC50:  480nMAssay Description:Inhibition of VLA-4 binding to recombinant human VCAM using Ramos cell assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed