Compile Data Set for Download or QSAR
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Found 4 Enz. Inhib. hit(s) with all data for entry = 50010031
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50079857((R)-2-[2,6-Dibromo-4-(6-bromo-benzo[b]naphtho[2,3-...)
Affinity DataIC50:  61nMAssay Description:Compound was evaluated for the inhibitory activity against recombinant Protein-tyrosine phosphatase 1B using, phosphotyrosyl dodecapeptide [TRDI(P)YE...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50090172((R)-2-[4-(2,3-Dimethyl-1-oxa-9-thia-cyclopenta[b]f...)
Affinity DataIC50:  74nMAssay Description:Compound was evaluated for the inhibitory activity against recombinant Protein-tyrosine phosphatase 1B using, phosphotyrosyl dodecapeptide [TRDI(P)YE...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50090173((R)-2-(4-Benzo[b]naphtho[2,3-d]thiophen-11-yl-2,6-...)
Affinity DataIC50:  179nMAssay Description:Compound was evaluated for the inhibitory activity against recombinant Protein-tyrosine phosphatase 1B using, phosphotyrosyl dodecapeptide [TRDI(P)YE...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50090171((R)-2-[4-(2,3-Dimethyl-1-oxa-9-thia-cyclopenta[b]f...)
Affinity DataIC50:  284nMAssay Description:Compound was evaluated for the inhibitory activity against recombinant Protein-tyrosine phosphatase 1B using, phosphotyrosyl dodecapeptide [TRDI(P)YE...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed