Compile Data Set for Download or QSAR
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Found 24 Enz. Inhib. hit(s) with all data for entry = 50010410
TargetNociceptin receptor(Homo sapiens (Human))
Central Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50094648(CHEMBL139776 | N-(4-Amino-2-methyl-quinolin-6-yl)-...)
Affinity DataKi:  1.80nMAssay Description:Compound was evaluated for its ability to displace [3H]nociceptin ( 0.5 nM ) binding from Opioid receptor like 1 expressed in HeLa cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNociceptin receptor(Homo sapiens (Human))
Central Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50094640(CHEMBL140640 | N-(4-Amino-2-propyl-quinolin-6-yl)-...)
Affinity DataKi:  1.80nMAssay Description:Compound was evaluated for its ability to displace [3H]nociceptin ( 0.5 nM ) binding from Opioid receptor like 1 expressed in HeLa cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNociceptin receptor(Homo sapiens (Human))
Central Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50094650(CHEMBL434060 | N-(4-Amino-2-ethyl-quinolin-6-yl)-2...)
Affinity DataKi:  1.80nMAssay Description:Compound was evaluated for its ability to displace [3H]nociceptin ( 0.5 nM ) binding from Opioid receptor like 1 expressed in HeLa cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNociceptin receptor(Homo sapiens (Human))
Central Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50094651(CHEMBL342580 | N-(4-Amino-2-methyl-quinolin-6-yl)-...)
Affinity DataKi:  2.20nMAssay Description:Compound was evaluated for its ability to displace [3H]nociceptin ( 0.5 nM ) binding from Opioid receptor like 1 expressed in HeLa cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNociceptin receptor(Homo sapiens (Human))
Central Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50094638(CHEMBL337128 | N-(4-Amino-2-methyl-quinolin-6-yl)-...)
Affinity DataKi:  2.30nMAssay Description:Compound was evaluated for its ability to displace [3H]nociceptin ( 0.5 nM ) binding from Opioid receptor like 1 expressed in HeLa cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNociceptin receptor(Homo sapiens (Human))
Central Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50094642(CHEMBL142454 | N-(4-Amino-2-methyl-quinolin-6-yl)-...)
Affinity DataKi:  2.60nMAssay Description:Compound was evaluated for its ability to displace [3H]nociceptin ( 0.5 nM ) binding from Opioid receptor like 1 expressed in HeLa cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNociceptin receptor(Homo sapiens (Human))
Central Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50094646(CHEMBL139934 | N-(4-Amino-2-methyl-quinolin-6-yl)-...)
Affinity DataKi:  6.5nMAssay Description:Compound was evaluated for its ability to displace [3H]nociceptin ( 0.5 nM ) binding from Opioid receptor like 1 expressed in HeLa cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNociceptin receptor(Homo sapiens (Human))
Central Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50094636(CHEMBL140103 | N-(4-Amino-2-methyl-quinolin-6-yl)-...)
Affinity DataKi:  7nMAssay Description:Compound was evaluated for its ability to displace [3H]nociceptin ( 0.5 nM ) binding from Opioid receptor like 1 expressed in HeLa cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNociceptin receptor(Homo sapiens (Human))
Central Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50094634(CHEMBL140979 | N-(4-Amino-2-methyl-quinolin-6-yl)-...)
Affinity DataKi:  8.20nMAssay Description:Compound was evaluated for its ability to displace [3H]nociceptin ( 0.5 nM ) binding from Opioid receptor like 1 expressed in HeLa cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNociceptin receptor(Homo sapiens (Human))
Central Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50094644(CHEMBL140519 | N-(4-Amino-2-methyl-quinolin-6-yl)-...)
Affinity DataKi:  12nMAssay Description:Compound was evaluated for its ability to displace [3H]nociceptin ( 0.5 nM ) binding from Opioid receptor like 1 expressed in HeLa cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNociceptin receptor(Homo sapiens (Human))
Central Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50094639(CHEMBL142999 | N-(4-Amino-2-methyl-quinolin-6-yl)-...)
Affinity DataKi:  13nMAssay Description:Compound was evaluated for its ability to displace [3H]nociceptin ( 0.5 nM ) binding from Opioid receptor like 1 expressed in HeLa cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNociceptin receptor(Homo sapiens (Human))
Central Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50094647(CHEMBL143605 | N-(4-Amino-2-methyl-quinolin-6-yl)-...)
Affinity DataKi:  20nMAssay Description:Compound was evaluated for its ability to displace [3H]nociceptin ( 0.5 nM ) binding from Opioid receptor like 1 expressed in HeLa cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNociceptin receptor(Homo sapiens (Human))
Central Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50094649(CHEMBL140580 | N-(1-Amino-3-methyl-isoquinolin-7-y...)
Affinity DataKi:  37nMAssay Description:Compound was evaluated for its ability to displace [3H]nociceptin ( 0.5 nM ) binding from Opioid receptor like 1 expressed in HeLa cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNociceptin receptor(Homo sapiens (Human))
Central Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50094637(CHEMBL139566 | N-(4-Amino-2-methyl-quinolin-6-yl)-...)
Affinity DataKi:  47nMAssay Description:Compound was evaluated for its ability to displace [3H]nociceptin ( 0.5 nM ) binding from Opioid receptor like 1 expressed in HeLa cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNociceptin receptor(Homo sapiens (Human))
Central Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50094635(CHEMBL336238 | N-(4-Amino-2-methyl-quinolin-6-yl)-...)
Affinity DataKi:  51nMAssay Description:Compound was evaluated for its ability to displace [3H]-nociceptin ( 0.5 nM ) binding from Opioid receptor like 1 expressed in HeLa cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNociceptin receptor(Homo sapiens (Human))
Central Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50094643(CHEMBL358306 | N-(4-Amino-2-methyl-quinolin-6-yl)-...)
Affinity DataKi:  80nMAssay Description:Compound was evaluated for its ability to displace [3H]-nociceptin ( 0.5 nM ) binding from Opioid receptor like 1 expressed in HeLa cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNociceptin receptor(Homo sapiens (Human))
Central Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50094641(CHEMBL422641 | N-(4-Amino-2-methyl-quinolin-6-yl)-...)
Affinity DataKi:  82nMAssay Description:Compound was evaluated for its ability to displace [3H]nociceptin ( 0.5 nM ) binding from Opioid receptor like 1 expressed in HeLa cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNociceptin receptor(Homo sapiens (Human))
Central Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50094645(CHEMBL143243 | N-(4-Amino-quinolin-6-yl)-2-(4-chlo...)
Affinity DataKi:  86nMAssay Description:Compound was evaluated for its ability to displace [3H]nociceptin ( 0.5 nM ) binding from Opioid receptor like 1 expressed in HeLa cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNociceptin receptor(Homo sapiens (Human))
Central Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50094652(CHEMBL343424 | N-(4-Amino-2-methyl-quinolin-6-yl)-...)
Affinity DataKi:  89nMAssay Description:Compound was evaluated for its ability to displace [3H]nociceptin ( 0.5 nM ) binding from Opioid receptor like 1 expressed in HeLa cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
Central Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50094634(CHEMBL140979 | N-(4-Amino-2-methyl-quinolin-6-yl)-...)
Affinity DataKi:  103nMAssay Description:Inhibition of [3H]diprenorphine (0.33 nM) binding from human Opioid receptor mu 1 expressed in CHO-K1 cells.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNociceptin receptor(Homo sapiens (Human))
Central Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50094653(CHEMBL141078 | N-(4-Amino-2-methyl-quinolin-6-yl)-...)
Affinity DataKi:  121nMAssay Description:Compound was evaluated for its ability to displace [3H]nociceptin ( 0.5 nM ) binding from Opioid receptor like 1 expressed in HeLa cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNociceptin receptor(Homo sapiens (Human))
Central Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50094654(Biphenyl-2-carboxylic acid (4-amino-2-methyl-quino...)
Affinity DataKi:  369nMAssay Description:Compound was evaluated for its ability to displace [3H]nociceptin ( 0.5 nM ) binding from Opioid receptor like 1 expressed in HeLa cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Central Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50094634(CHEMBL140979 | N-(4-Amino-2-methyl-quinolin-6-yl)-...)
Affinity DataKi:  1.06E+3nMAssay Description:Inhibition of [3H]naltrindole (0.55 nM) binding from human Opioid receptor kappa 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
Central Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50094634(CHEMBL140979 | N-(4-Amino-2-methyl-quinolin-6-yl)-...)
Affinity DataKi:  8.65E+3nMAssay Description:Inhibition of [3H]naltrindole (0.55 nM) binding from human Opioid receptor delta 1 expressed in CHO-K1 cells.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed