Compile Data Set for Download or QSAR
maximum 50k data
Found 43 Enz. Inhib. hit(s) with all data for entry = 50035101
Target72 kDa type IV collagenase(Homo sapiens (Human))
Pharmacia

Curated by ChEMBL
LigandPNGBDBM50082556((S)-2,2-Dimethyl-4-[4-(pyridin-4-yloxy)-benzenesul...)
Affinity DataIC50:  0.300nMAssay Description:50 percent inhibition of human Matrix metalloprotease-2 by the cleavage of fluorogenic peptide MCA-Pro-Leu-Gly-Leu-Dpa-ala-Arg-NH2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Pharmacia

Curated by ChEMBL
LigandPNGBDBM11863(4-({[4-(4-chlorophenoxy)benzene]sulfonyl}methyl)-N...)
Affinity DataIC50:  0.400nMAssay Description:50 percent inhibition of human Matrix metalloprotease-2 by the cleavage of fluorogenic peptide MCA-Pro-Leu-Gly-Leu-Dpa-ala-Arg-NH2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Pharmacia

Curated by ChEMBL
LigandPNGBDBM50082556((S)-2,2-Dimethyl-4-[4-(pyridin-4-yloxy)-benzenesul...)
Affinity DataIC50:  0.5nMAssay Description:50 percent inhibition of human Matrix metalloprotease-13 by the cleavage of fluorogenic peptide MCA-Pro-Leu-Gly-Leu-Dpa-ala-Arg-NH2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Pharmacia

Curated by ChEMBL
LigandPNGBDBM11863(4-({[4-(4-chlorophenoxy)benzene]sulfonyl}methyl)-N...)
Affinity DataIC50:  0.600nMAssay Description:50 percent inhibition of human Matrix metalloprotease-13 by the cleavage of fluorogenic peptide MCA-Pro-Leu-Gly-Leu-Dpa-ala-Arg-NH2More data for this Ligand-Target Pair
Target72 kDa type IV collagenase(Homo sapiens (Human))
Pharmacia

Curated by ChEMBL
LigandPNGBDBM50063917((2S,3R)-N(4)-[(2S)-3,3-dimethyl-1-(methylamino)-1-...)
Affinity DataIC50:  0.75nMAssay Description:50 percent inhibition of human Matrix metalloprotease-2 by the cleavage of fluorogenic peptide MCA-Pro-Leu-Gly-Leu-Dpa-ala-Arg-NH2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

Target72 kDa type IV collagenase(Homo sapiens (Human))
Pharmacia

Curated by ChEMBL
LigandPNGBDBM50095222(CHEMBL83209 | N-Hydroxy-2-[4-(4-trifluoromethyl-ph...)
Affinity DataIC50:  1.30nMAssay Description:50 percent inhibition of human Matrix metalloprotease-2 by the cleavage of fluorogenic peptide MCA-Pro-Leu-Gly-Leu-Dpa-ala-Arg-NH2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Pharmacia

Curated by ChEMBL
LigandPNGBDBM50063917((2S,3R)-N(4)-[(2S)-3,3-dimethyl-1-(methylamino)-1-...)
Affinity DataIC50:  2nMAssay Description:50 percent inhibition of human Matrix metalloprotease-13 by the cleavage of fluorogenic peptide MCA-Pro-Leu-Gly-Leu-Dpa-ala-Arg-NH2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

Target72 kDa type IV collagenase(Homo sapiens (Human))
Pharmacia

Curated by ChEMBL
LigandPNGBDBM50095218(CHEMBL310008 | N-Hydroxy-2-[4-(4-trifluoromethoxy-...)
Affinity DataIC50:  2nMAssay Description:50 percent inhibition of human Matrix metalloprotease-2 by the cleavage of fluorogenic peptide MCA-Pro-Leu-Gly-Leu-Dpa-ala-Arg-NH2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Pharmacia

Curated by ChEMBL
LigandPNGBDBM50063917((2S,3R)-N(4)-[(2S)-3,3-dimethyl-1-(methylamino)-1-...)
Affinity DataIC50:  2.90nMAssay Description:50 percent inhibition of human Matrix metalloprotease-1 by the cleavage of fluorogenic peptide MCA-Pro-Leu-Gly-Leu-Dpa-ala-Arg-NH2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

Target72 kDa type IV collagenase(Homo sapiens (Human))
Pharmacia

Curated by ChEMBL
LigandPNGBDBM50095225(2-Fluoro-N-hydroxy-6-[4-(4-trifluoromethyl-phenoxy...)
Affinity DataIC50:  3.30nMAssay Description:50 percent inhibition of human Matrix metalloprotease-2 by the cleavage of fluorogenic peptide MCA-Pro-Leu-Gly-Leu-Dpa-ala-Arg-NH2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Pharmacia

Curated by ChEMBL
LigandPNGBDBM50095225(2-Fluoro-N-hydroxy-6-[4-(4-trifluoromethyl-phenoxy...)
Affinity DataIC50:  12nMAssay Description:50 percent inhibition of human Matrix metalloprotease-13 by the cleavage of fluorogenic peptide MCA-Pro-Leu-Gly-Leu-Dpa-ala-Arg-NH2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Pharmacia

Curated by ChEMBL
LigandPNGBDBM50082556((S)-2,2-Dimethyl-4-[4-(pyridin-4-yloxy)-benzenesul...)
Affinity DataIC50:  24nMAssay Description:50 percent inhibition of human Matrix metalloprotease-1 by the cleavage of fluorogenic peptide MCA-Pro-Leu-Gly-Leu-Dpa-ala-Arg-NH2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Pharmacia

Curated by ChEMBL
LigandPNGBDBM50095222(CHEMBL83209 | N-Hydroxy-2-[4-(4-trifluoromethyl-ph...)
Affinity DataIC50:  28nMAssay Description:50 percent inhibition of human Matrix metalloprotease-13 by the cleavage of fluorogenic peptide MCA-Pro-Leu-Gly-Leu-Dpa-ala-Arg-NH2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Pharmacia

Curated by ChEMBL
LigandPNGBDBM50095218(CHEMBL310008 | N-Hydroxy-2-[4-(4-trifluoromethoxy-...)
Affinity DataIC50:  33nMAssay Description:50 percent inhibition of human Matrix metalloprotease-13 by the cleavage of fluorogenic peptide MCA-Pro-Leu-Gly-Leu-Dpa-ala-Arg-NH2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Pharmacia

Curated by ChEMBL
LigandPNGBDBM50095224(CHEMBL94467 | N-Hydroxy-2-[4-(4-trifluoromethyl-be...)
Affinity DataIC50:  35nMAssay Description:50 percent inhibition of human Matrix metalloprotease-2 by the cleavage of fluorogenic peptide MCA-Pro-Leu-Gly-Leu-Dpa-ala-Arg-NH2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Pharmacia

Curated by ChEMBL
LigandPNGBDBM50095221(CHEMBL94872 | N-Hydroxy-2-(4-phenyl-piperidine-1-s...)
Affinity DataIC50:  70nMAssay Description:50 percent inhibition of human Matrix metalloprotease-2 by the cleavage of fluorogenic peptide MCA-Pro-Leu-Gly-Leu-Dpa-ala-Arg-NH2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Pharmacia

Curated by ChEMBL
LigandPNGBDBM50095219(2-(4-Benzyl-piperidine-1-sulfonyl)-N-hydroxy-benza...)
Affinity DataIC50:  148nMAssay Description:50 percent inhibition of human Matrix metalloprotease-2 by the cleavage of fluorogenic peptide MCA-Pro-Leu-Gly-Leu-Dpa-ala-Arg-NH2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Pharmacia

Curated by ChEMBL
LigandPNGBDBM50095221(CHEMBL94872 | N-Hydroxy-2-(4-phenyl-piperidine-1-s...)
Affinity DataIC50:  520nMAssay Description:50 percent inhibition of human Matrix metalloprotease-13 by the cleavage of fluorogenic peptide MCA-Pro-Leu-Gly-Leu-Dpa-ala-Arg-NH2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Pharmacia

Curated by ChEMBL
LigandPNGBDBM11863(4-({[4-(4-chlorophenoxy)benzene]sulfonyl}methyl)-N...)
Affinity DataIC50:  800nMAssay Description:50 percent inhibition of human Matrix metalloprotease-1 by the cleavage of fluorogenic peptide MCA-Pro-Leu-Gly-Leu-Dpa-ala-Arg-NH2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Pharmacia

Curated by ChEMBL
LigandPNGBDBM50095224(CHEMBL94467 | N-Hydroxy-2-[4-(4-trifluoromethyl-be...)
Affinity DataIC50:  900nMAssay Description:50 percent inhibition of human Matrix metalloprotease-13 by the cleavage of fluorogenic peptide MCA-Pro-Leu-Gly-Leu-Dpa-ala-Arg-NH2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Pharmacia

Curated by ChEMBL
LigandPNGBDBM50095219(2-(4-Benzyl-piperidine-1-sulfonyl)-N-hydroxy-benza...)
Affinity DataIC50:  1.00E+3nMAssay Description:50 percent inhibition of human Matrix metalloprotease-13 by the cleavage of fluorogenic peptide MCA-Pro-Leu-Gly-Leu-Dpa-ala-Arg-NH2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Pharmacia

Curated by ChEMBL
LigandPNGBDBM50095217(2-(4-Benzoyl-piperazine-1-sulfonyl)-N-hydroxy-benz...)
Affinity DataIC50:  1.00E+3nMAssay Description:50 percent inhibition of human Matrix metalloprotease-2 by the cleavage of fluorogenic peptide MCA-Pro-Leu-Gly-Leu-Dpa-ala-Arg-NH2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Pharmacia

Curated by ChEMBL
LigandPNGBDBM50095215(CHEMBL330078 | N-Hydroxy-2-[3-(4-trifluoromethyl-p...)
Affinity DataIC50:  1.80E+3nMAssay Description:50 percent inhibition of human Matrix metalloprotease-2 by the cleavage of fluorogenic peptide MCA-Pro-Leu-Gly-Leu-Dpa-ala-Arg-NH2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Pharmacia

Curated by ChEMBL
LigandPNGBDBM50095215(CHEMBL330078 | N-Hydroxy-2-[3-(4-trifluoromethyl-p...)
Affinity DataIC50:  2.00E+3nMAssay Description:50 percent inhibition of human Matrix metalloprotease-13 by the cleavage of fluorogenic peptide MCA-Pro-Leu-Gly-Leu-Dpa-ala-Arg-NH2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Pharmacia

Curated by ChEMBL
LigandPNGBDBM50095213(CHEMBL97478 | N-hydroxy-2-({3-[(4-methoxybenzoyl)a...)
Affinity DataIC50:  2.20E+3nMAssay Description:50 percent inhibition of human Matrix metalloprotease-13 by the cleavage of fluorogenic peptide MCA-Pro-Leu-Gly-Leu-Dpa-ala-Arg-NH2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Pharmacia

Curated by ChEMBL
LigandPNGBDBM50095213(CHEMBL97478 | N-hydroxy-2-({3-[(4-methoxybenzoyl)a...)
Affinity DataIC50:  2.30E+3nMAssay Description:50 percent inhibition of human Matrix metalloprotease-2 by the cleavage of fluorogenic peptide MCA-Pro-Leu-Gly-Leu-Dpa-ala-Arg-NH2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Pharmacia

Curated by ChEMBL
LigandPNGBDBM50095220(CHEMBL94324 | N-Hydroxy-2-(4-phenoxy-phenylsulfamo...)
Affinity DataIC50:  3.50E+3nMAssay Description:50 percent inhibition of human Matrix metalloprotease-2 by the cleavage of fluorogenic peptide MCA-Pro-Leu-Gly-Leu-Dpa-ala-Arg-NH2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Pharmacia

Curated by ChEMBL
LigandPNGBDBM50095217(2-(4-Benzoyl-piperazine-1-sulfonyl)-N-hydroxy-benz...)
Affinity DataIC50:  6.70E+3nMAssay Description:50 percent inhibition of human Matrix metalloprotease-13 by the cleavage of fluorogenic peptide MCA-Pro-Leu-Gly-Leu-Dpa-ala-Arg-NH2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Pharmacia

Curated by ChEMBL
LigandPNGBDBM50095220(CHEMBL94324 | N-Hydroxy-2-(4-phenoxy-phenylsulfamo...)
Affinity DataIC50:  9.00E+3nMAssay Description:50 percent inhibition of human Matrix metalloprotease-13 by the cleavage of fluorogenic peptide MCA-Pro-Leu-Gly-Leu-Dpa-ala-Arg-NH2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Pharmacia

Curated by ChEMBL
LigandPNGBDBM50095214(CHEMBL94828 | N-Hydroxy-2-(4-methoxy-phenylsulfamo...)
Affinity DataIC50: >1.00E+4nMAssay Description:50 percent inhibition of human Matrix metalloprotease-13 by the cleavage of fluorogenic peptide MCA-Pro-Leu-Gly-Leu-Dpa-ala-Arg-NH2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Pharmacia

Curated by ChEMBL
LigandPNGBDBM50095225(2-Fluoro-N-hydroxy-6-[4-(4-trifluoromethyl-phenoxy...)
Affinity DataIC50: >1.00E+4nMAssay Description:50 percent inhibition of human Matrix metalloprotease-1 by the cleavage of fluorogenic peptide MCA-Pro-Leu-Gly-Leu-Dpa-ala-Arg-NH2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Pharmacia

Curated by ChEMBL
LigandPNGBDBM50095213(CHEMBL97478 | N-hydroxy-2-({3-[(4-methoxybenzoyl)a...)
Affinity DataIC50: >1.00E+4nMAssay Description:50 percent inhibition of human Matrix metalloprotease-1 by the cleavage of fluorogenic peptide MCA-Pro-Leu-Gly-Leu-Dpa-ala-Arg-NH2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Pharmacia

Curated by ChEMBL
LigandPNGBDBM50095218(CHEMBL310008 | N-Hydroxy-2-[4-(4-trifluoromethoxy-...)
Affinity DataIC50: >1.00E+4nMAssay Description:50 percent inhibition of human Matrix metalloprotease-1 by the cleavage of fluorogenic peptide MCA-Pro-Leu-Gly-Leu-Dpa-ala-Arg-NH2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Pharmacia

Curated by ChEMBL
LigandPNGBDBM50095219(2-(4-Benzyl-piperidine-1-sulfonyl)-N-hydroxy-benza...)
Affinity DataIC50: >1.00E+4nMAssay Description:50 percent inhibition of human Matrix metalloprotease-1 by the cleavage of fluorogenic peptide MCA-Pro-Leu-Gly-Leu-Dpa-ala-Arg-NH2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Pharmacia

Curated by ChEMBL
LigandPNGBDBM50095224(CHEMBL94467 | N-Hydroxy-2-[4-(4-trifluoromethyl-be...)
Affinity DataIC50: >1.00E+4nMAssay Description:50 percent inhibition of human Matrix metalloprotease-1 by the cleavage of fluorogenic peptide MCA-Pro-Leu-Gly-Leu-Dpa-ala-Arg-NH2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Pharmacia

Curated by ChEMBL
LigandPNGBDBM50095222(CHEMBL83209 | N-Hydroxy-2-[4-(4-trifluoromethyl-ph...)
Affinity DataIC50: >1.00E+4nMAssay Description:50 percent inhibition of human Matrix metalloprotease-1 by the cleavage of fluorogenic peptide MCA-Pro-Leu-Gly-Leu-Dpa-ala-Arg-NH2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Pharmacia

Curated by ChEMBL
LigandPNGBDBM50095221(CHEMBL94872 | N-Hydroxy-2-(4-phenyl-piperidine-1-s...)
Affinity DataIC50: >1.00E+4nMAssay Description:50 percent inhibition of human Matrix metalloprotease-1 by the cleavage of fluorogenic peptide MCA-Pro-Leu-Gly-Leu-Dpa-ala-Arg-NH2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Pharmacia

Curated by ChEMBL
LigandPNGBDBM50095223(2-Benzylsulfamoyl-N-hydroxy-benzamide | CHEMBL4213...)
Affinity DataIC50: >1.00E+4nMAssay Description:50 percent inhibition of human Matrix metalloprotease-13 by the cleavage of fluorogenic peptide MCA-Pro-Leu-Gly-Leu-Dpa-ala-Arg-NH2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Pharmacia

Curated by ChEMBL
LigandPNGBDBM50095220(CHEMBL94324 | N-Hydroxy-2-(4-phenoxy-phenylsulfamo...)
Affinity DataIC50: >1.00E+4nMAssay Description:50 percent inhibition of human Matrix metalloprotease-1 by the cleavage of fluorogenic peptide MCA-Pro-Leu-Gly-Leu-Dpa-ala-Arg-NH2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Pharmacia

Curated by ChEMBL
LigandPNGBDBM50095223(2-Benzylsulfamoyl-N-hydroxy-benzamide | CHEMBL4213...)
Affinity DataIC50: >1.00E+4nMAssay Description:50 percent inhibition of human Matrix metalloprotease-1 by the cleavage of fluorogenic peptide MCA-Pro-Leu-Gly-Leu-Dpa-ala-Arg-NH2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Pharmacia

Curated by ChEMBL
LigandPNGBDBM50095217(2-(4-Benzoyl-piperazine-1-sulfonyl)-N-hydroxy-benz...)
Affinity DataIC50: >1.00E+4nMAssay Description:50 percent inhibition of human Matrix metalloprotease-1 by the cleavage of fluorogenic peptide MCA-Pro-Leu-Gly-Leu-Dpa-ala-Arg-NH2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Pharmacia

Curated by ChEMBL
LigandPNGBDBM50095215(CHEMBL330078 | N-Hydroxy-2-[3-(4-trifluoromethyl-p...)
Affinity DataIC50: >1.00E+4nMAssay Description:50 percent inhibition of human Matrix metalloprotease-1 by the cleavage of fluorogenic peptide MCA-Pro-Leu-Gly-Leu-Dpa-ala-Arg-NH2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Pharmacia

Curated by ChEMBL
LigandPNGBDBM50095214(CHEMBL94828 | N-Hydroxy-2-(4-methoxy-phenylsulfamo...)
Affinity DataIC50: >1.00E+4nMAssay Description:50 percent inhibition of human Matrix metalloprotease-1 by the cleavage of fluorogenic peptide MCA-Pro-Leu-Gly-Leu-Dpa-ala-Arg-NH2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed