Compile Data Set for Download or QSAR
maximum 50k data
Found 36 Enz. Inhib. hit(s) with all data for entry = 50042170
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Celltech R&D

Curated by ChEMBL
LigandPNGBDBM50114276((S)-2-[((S)-3-Acetyl-thiazolidine-4-carbonyl)-amin...)
Affinity DataIC50:  0.5nMAssay Description:Inhibition of VLA-4 from HL60 lysate in a protein-based ligand binding assay.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Celltech R&D

Curated by ChEMBL
LigandPNGBDBM50114291((S)-2-[(3,5-Dichloro-pyridine-4-carbonyl)-amino]-3...)
Affinity DataIC50:  0.5nMAssay Description:Inhibition of VLA-4 expressed in Jurkat cell line, in a cell-based adhesion assay.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Celltech R&D

Curated by ChEMBL
LigandPNGBDBM50114276((S)-2-[((S)-3-Acetyl-thiazolidine-4-carbonyl)-amin...)
Affinity DataIC50:  0.600nMAssay Description:Inhibition of VLA-4 from HL60 lysate in a protein-based ligand binding assay.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Celltech R&D

Curated by ChEMBL
LigandPNGBDBM50114291((S)-2-[(3,5-Dichloro-pyridine-4-carbonyl)-amino]-3...)
Affinity DataIC50:  0.900nMAssay Description:Inhibition of VLA-4 from HL60 lysate in a protein-based ligand binding assay.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Celltech R&D

Curated by ChEMBL
LigandPNGBDBM50114292(1-[4-((S)-1-Carboxy-2-{4-[(3,5-dichloro-pyridine-4...)
Affinity DataIC50:  6nMAssay Description:Inhibition of VLA-4 expressed in Jurkat cell line, in a cell-based adhesion assay.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Celltech R&D

Curated by ChEMBL
LigandPNGBDBM50114277((S)-3-{4-[(3,5-Dichloro-pyridine-4-carbonyl)-amino...)
Affinity DataIC50:  7nMAssay Description:Inhibition of VLA-4 from HL60 lysate in a protein-based ligand binding assay.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Celltech R&D

Curated by ChEMBL
LigandPNGBDBM50114280((S)-3-{4-[(3,5-Dichloro-pyridine-4-carbonyl)-amino...)
Affinity DataIC50:  8nMAssay Description:Inhibition of VLA-4 from HL60 lysate in a protein-based ligand binding assay.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Celltech R&D

Curated by ChEMBL
LigandPNGBDBM50114289((S)-3-{4-[(3,5-Dichloro-pyridine-4-carbonyl)-amino...)
Affinity DataIC50:  14nMAssay Description:Inhibition of VLA-4 expressed in Jurkat cell line, in a cell-based adhesion assay.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Celltech R&D

Curated by ChEMBL
LigandPNGBDBM50114288((S)-3-{4-[(3,5-Dichloro-pyridine-4-carbonyl)-amino...)
Affinity DataIC50:  16nMAssay Description:Inhibition of VLA-4 expressed in Jurkat cell line, in a cell-based adhesion assay.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Celltech R&D

Curated by ChEMBL
LigandPNGBDBM50114278((S)-3-{4-[(3,5-Dichloro-pyridine-4-carbonyl)-amino...)
Affinity DataIC50:  25nMAssay Description:Inhibition of VLA-4 expressed in Jurkat cell line, in a cell-based adhesion assay.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Celltech R&D

Curated by ChEMBL
LigandPNGBDBM50114284((S)-3-{4-[(3,5-Dichloro-pyridine-4-carbonyl)-amino...)
Affinity DataIC50:  25nMAssay Description:Inhibition of VLA-4 expressed in Jurkat cell line, in a cell-based adhesion assay.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Celltech R&D

Curated by ChEMBL
LigandPNGBDBM50114283((S)-3-{4-[(3,5-Dichloro-pyridine-4-carbonyl)-amino...)
Affinity DataIC50:  30nMAssay Description:Inhibition of VLA-4 expressed in Jurkat cell line, in a cell-based adhesion assay.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Celltech R&D

Curated by ChEMBL
LigandPNGBDBM50114294((S)-3-[4-(2,6-Dichloro-benzoylamino)-phenyl]-2-(4,...)
Affinity DataIC50:  30nMAssay Description:Inhibition of VLA-4 from HL60 lysate in a protein-based ligand binding assay.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Celltech R&D

Curated by ChEMBL
LigandPNGBDBM50114279((S)-3-{4-[(3,5-Dichloro-pyridine-4-carbonyl)-amino...)
Affinity DataIC50:  45nMAssay Description:Inhibition of VLA-4 from HL60 lysate in a protein-based ligand binding assay.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Celltech R&D

Curated by ChEMBL
LigandPNGBDBM50114290((S)-2-(4,6-Dimethoxy-[1,3,5]triazin-2-ylamino)-3-[...)
Affinity DataIC50:  50nMAssay Description:Inhibition of VLA-4 expressed in Jurkat cell line, in a cell-based adhesion assay.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Celltech R&D

Curated by ChEMBL
LigandPNGBDBM50114281((S)-3-{4-[(3,5-Dichloro-pyridine-4-carbonyl)-amino...)
Affinity DataIC50:  50nMAssay Description:Inhibition of VLA-4 expressed in Jurkat cell line, in a cell-based adhesion assay.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Celltech R&D

Curated by ChEMBL
LigandPNGBDBM50114285((S)-3-{4-[(3,5-Dichloro-pyridine-4-carbonyl)-amino...)
Affinity DataIC50:  70nMAssay Description:Inhibition of VLA-4 expressed in Jurkat cell line, in a cell-based adhesion assay.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Celltech R&D

Curated by ChEMBL
LigandPNGBDBM50114287((S)-2-(6-Chloro-pyrimidin-4-ylamino)-3-{4-[(3,5-di...)
Affinity DataIC50:  80nMAssay Description:Inhibition of VLA-4 from HL60 lysate in a protein-based ligand binding assay.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Celltech R&D

Curated by ChEMBL
LigandPNGBDBM50114292(1-[4-((S)-1-Carboxy-2-{4-[(3,5-dichloro-pyridine-4...)
Affinity DataIC50:  240nMAssay Description:Inhibition of VLA-4 from HL60 lysate in a protein-based ligand binding assay.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Celltech R&D

Curated by ChEMBL
LigandPNGBDBM50114282((S)-3-{4-[(3,5-Dichloro-pyridine-4-carbonyl)-amino...)
Affinity DataIC50:  260nMAssay Description:Inhibition of VLA-4 expressed in Jurkat cell line, in a cell-based adhesion assay.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Celltech R&D

Curated by ChEMBL
LigandPNGBDBM50114279((S)-3-{4-[(3,5-Dichloro-pyridine-4-carbonyl)-amino...)
Affinity DataIC50:  300nMAssay Description:Inhibition of VLA-4 from HL60 lysate in a protein-based ligand binding assay.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Celltech R&D

Curated by ChEMBL
LigandPNGBDBM50114277((S)-3-{4-[(3,5-Dichloro-pyridine-4-carbonyl)-amino...)
Affinity DataIC50:  320nMAssay Description:Inhibition of VLA-4 expressed in Jurkat cell line, in a cell-based adhesion assay.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Celltech R&D

Curated by ChEMBL
LigandPNGBDBM50114283((S)-3-{4-[(3,5-Dichloro-pyridine-4-carbonyl)-amino...)
Affinity DataIC50:  320nMAssay Description:Inhibition of VLA-4 expressed in Jurkat cell line, in a cell-based adhesion assay.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Celltech R&D

Curated by ChEMBL
LigandPNGBDBM50114289((S)-3-{4-[(3,5-Dichloro-pyridine-4-carbonyl)-amino...)
Affinity DataIC50:  510nMAssay Description:Inhibition of VLA-4 expressed in Jurkat cell line, in a cell-based adhesion assay.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Celltech R&D

Curated by ChEMBL
LigandPNGBDBM50114288((S)-3-{4-[(3,5-Dichloro-pyridine-4-carbonyl)-amino...)
Affinity DataIC50:  590nMAssay Description:Inhibition of VLA-4 expressed in Jurkat cell line, in a cell-based adhesion assay.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Celltech R&D

Curated by ChEMBL
LigandPNGBDBM50114284((S)-3-{4-[(3,5-Dichloro-pyridine-4-carbonyl)-amino...)
Affinity DataIC50:  740nMAssay Description:Inhibition of VLA-4 expressed in Jurkat cell line, in a cell-based adhesion assay.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Celltech R&D

Curated by ChEMBL
LigandPNGBDBM50114281((S)-3-{4-[(3,5-Dichloro-pyridine-4-carbonyl)-amino...)
Affinity DataIC50:  740nMAssay Description:Inhibition of VLA-4 expressed in Jurkat cell line, in a cell-based adhesion assay.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Celltech R&D

Curated by ChEMBL
LigandPNGBDBM50114280((S)-3-{4-[(3,5-Dichloro-pyridine-4-carbonyl)-amino...)
Affinity DataIC50:  900nMAssay Description:Inhibition of VLA-4 from HL60 lysate in a protein-based ligand binding assay.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Celltech R&D

Curated by ChEMBL
LigandPNGBDBM50114278((S)-3-{4-[(3,5-Dichloro-pyridine-4-carbonyl)-amino...)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibition of VLA-4 expressed in Jurkat cell line, in a cell-based adhesion assay.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Celltech R&D

Curated by ChEMBL
LigandPNGBDBM50114293((S)-3-[4-(2,6-Dichloro-benzyloxy)-phenyl]-2-(4,6-d...)
Affinity DataIC50:  1.50E+3nMAssay Description:Inhibition of VLA-4 from HL60 lysate in a protein-based ligand binding assay.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Celltech R&D

Curated by ChEMBL
LigandPNGBDBM50114285((S)-3-{4-[(3,5-Dichloro-pyridine-4-carbonyl)-amino...)
Affinity DataIC50:  1.62E+3nMAssay Description:Inhibition of VLA-4 from HL60 lysate in a protein-based ligand binding assay.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Celltech R&D

Curated by ChEMBL
LigandPNGBDBM50114287((S)-2-(6-Chloro-pyrimidin-4-ylamino)-3-{4-[(3,5-di...)
Affinity DataIC50:  1.70E+3nMAssay Description:Inhibition of VLA-4 from HL60 lysate in a protein-based ligand binding assay.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Celltech R&D

Curated by ChEMBL
LigandPNGBDBM50114282((S)-3-{4-[(3,5-Dichloro-pyridine-4-carbonyl)-amino...)
Affinity DataIC50:  2.50E+3nMAssay Description:Inhibition of VLA-4 from HL60 lysate in a protein-based ligand binding assay.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Celltech R&D

Curated by ChEMBL
LigandPNGBDBM50114294((S)-3-[4-(2,6-Dichloro-benzoylamino)-phenyl]-2-(4,...)
Affinity DataIC50:  4.00E+3nMAssay Description:Inhibition of VLA-4 from HL60 lysate in a protein-based ligand binding assay.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Celltech R&D

Curated by ChEMBL
LigandPNGBDBM50114290((S)-2-(4,6-Dimethoxy-[1,3,5]triazin-2-ylamino)-3-[...)
Affinity DataIC50:  4.60E+3nMAssay Description:Inhibition of VLA-4 from HL60 lysate in a protein-based ligand binding assay.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Celltech R&D

Curated by ChEMBL
LigandPNGBDBM50114286((S)-3-{4-[(3,5-Dichloro-pyridine-4-carbonyl)-methy...)
Affinity DataIC50:  5.50E+3nMAssay Description:Inhibition of VLA-4 from HL60 lysate in a protein-based ligand binding assay.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed