Compile Data Set for Download or QSAR
maximum 50k data
Found 28 Enz. Inhib. hit(s) with all data for entry = 50012903
TargetProthrombin(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50067797(CHEMBL19080 | L-37378 | N-(6-Amino-2-methyl-pyridi...)
Affinity DataKi:  0.800nMAssay Description:Inhibition of ThrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50124086(2-[6-Methyl-2-oxo-3-(2-pyridin-2-yl-ethylamino)-2H...)
Affinity DataKi:  1.20nMAssay Description:Inhibition of ThrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50124093(CHEMBL355730 | N-(1H-Indol-5-ylmethyl)-2-[6-methyl...)
Affinity DataKi:  1.60nMAssay Description:Inhibition of ThrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50124091(2-[6-Methyl-2-oxo-3-(2-pyridin-2-yl-ethylamino)-2H...)
Affinity DataKi:  3.20nMAssay Description:Inhibition of ThrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50124092(2-(6-Methyl-2-oxo-3-phenethylamino-2H-pyrazin-1-yl...)
Affinity DataKi:  3.70nMAssay Description:Inhibition of ThrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50124090(2-[6-Methyl-2-oxo-3-(2-pyridin-2-yl-ethylamino)-2H...)
Affinity DataKi:  6.60nMAssay Description:Inhibition of ThrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50124087(CHEMBL101563 | N-(1H-Benzoimidazol-5-ylmethyl)-2-(...)
Affinity DataKi:  11nMAssay Description:Inhibition of ThrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50124089(2-(6-Methyl-2-oxo-3-phenethylamino-2H-pyrazin-1-yl...)
Affinity DataKi:  11nMAssay Description:Inhibition of ThrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50124088(CHEMBL353213 | N-(5-Methyl-imidazo[1,2-a]pyridin-6...)
Affinity DataKi:  11nMAssay Description:Inhibition of ThrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50124097(CHEMBL422387 | N-(1H-Indol-5-ylmethyl)-2-(6-methyl...)
Affinity DataKi:  18nMAssay Description:Inhibition of ThrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50124095(2-(6-Methyl-2-oxo-3-phenethylamino-2H-pyrazin-1-yl...)
Affinity DataKi:  18nMAssay Description:Inhibition of ThrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50124098(CHEMBL167550 | N-Imidazo[1,2-a]pyridin-6-ylmethyl-...)
Affinity DataKi:  140nMAssay Description:Inhibition of ThrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50124096(CHEMBL166602 | N-Imidazo[1,2-a]pyridin-7-ylmethyl-...)
Affinity DataKi:  270nMAssay Description:Inhibition of ThrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50124094(CHEMBL166530 | N-(1H-Indol-6-ylmethyl)-2-(6-methyl...)
Affinity DataKi:  830nMAssay Description:Inhibition of ThrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50067797(CHEMBL19080 | L-37378 | N-(6-Amino-2-methyl-pyridi...)
Affinity DataKi:  1.80E+3nMAssay Description:Inhibition of TrypsinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50124087(CHEMBL101563 | N-(1H-Benzoimidazol-5-ylmethyl)-2-(...)
Affinity DataKi:  2.00E+3nMAssay Description:Inhibition of TrypsinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50124088(CHEMBL353213 | N-(5-Methyl-imidazo[1,2-a]pyridin-6...)
Affinity DataKi:  6.80E+3nMAssay Description:Inhibition of TrypsinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50124095(2-(6-Methyl-2-oxo-3-phenethylamino-2H-pyrazin-1-yl...)
Affinity DataKi: >1.00E+5nMAssay Description:Inhibition of TrypsinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50124089(2-(6-Methyl-2-oxo-3-phenethylamino-2H-pyrazin-1-yl...)
Affinity DataKi: >1.00E+5nMAssay Description:Inhibition of TrypsinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50124094(CHEMBL166530 | N-(1H-Indol-6-ylmethyl)-2-(6-methyl...)
Affinity DataKi: >1.00E+5nMAssay Description:Inhibition of TrypsinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50124097(CHEMBL422387 | N-(1H-Indol-5-ylmethyl)-2-(6-methyl...)
Affinity DataKi: >1.00E+5nMAssay Description:Inhibition of TrypsinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50124092(2-(6-Methyl-2-oxo-3-phenethylamino-2H-pyrazin-1-yl...)
Affinity DataKi: >1.00E+5nMAssay Description:Inhibition of TrypsinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50124098(CHEMBL167550 | N-Imidazo[1,2-a]pyridin-6-ylmethyl-...)
Affinity DataKi:  1.00E+5nMAssay Description:Inhibition of TrypsinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50124096(CHEMBL166602 | N-Imidazo[1,2-a]pyridin-7-ylmethyl-...)
Affinity DataKi:  1.20E+5nMAssay Description:Inhibition of TrypsinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50124090(2-[6-Methyl-2-oxo-3-(2-pyridin-2-yl-ethylamino)-2H...)
Affinity DataKi:  1.40E+5nMAssay Description:Inhibition of TrypsinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50124086(2-[6-Methyl-2-oxo-3-(2-pyridin-2-yl-ethylamino)-2H...)
Affinity DataKi:  2.00E+5nMAssay Description:Inhibition of TrypsinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50124093(CHEMBL355730 | N-(1H-Indol-5-ylmethyl)-2-[6-methyl...)
Affinity DataKi:  2.90E+5nMAssay Description:Inhibition of TrypsinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50124091(2-[6-Methyl-2-oxo-3-(2-pyridin-2-yl-ethylamino)-2H...)
Affinity DataKi: >1.00E+6nMAssay Description:Inhibition of TrypsinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed