BindingDB logo
myBDB logout

PubMed code 12617924

Compile data set for download or QSAR
Found 140 hits of Enzyme Inhibition Constant Data   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Peroxisome proliferator-activated receptor


(Homo sapiens (Human))
BDBM33283
PNG
((3-{4-[(3-phenyl-7-propyl-1,2-benzisoxazol-6-yl)ox...)
Show SMILES CCCc1c(OCCCCOc2cccc(CC(O)=O)c2)ccc2c(noc12)-c1ccccc1
Show InChI InChI=1S/C28H29NO5/c1-2-9-23-25(15-14-24-27(29-34-28(23)24)21-11-4-3-5-12-21)33-17-7-6-16-32-22-13-8-10-20(18-22)19-26(30)31/h3-5,8,10-15,18H,2,6-7,9,16-17,19H2,1H3,(H,30,31)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
0.300n/an/an/an/an/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Agonistic activity was determined in COS1 cells transfected with GAL 4-PPAR gamma receptor


Bioorg Med Chem Lett 13: 931-5 (2003)


Article DOI: 10.1016/s0960-894x(02)01029-6
BindingDB Entry DOI: 10.7270/Q2HX1C1Z
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor delta (PPAR delta)


(Homo sapiens (Human))
BDBM50124377
PNG
(3-{4-[3-(3-Phenyl-7-propyl-benzo[d]isoxazol-6-ylox...)
Show SMILES CCCc1c(OCCCOc2ccc(CCC(O)=O)cc2)ccc2c(noc12)-c1ccccc1
Show InChI InChI=1S/C28H29NO5/c1-2-7-23-25(16-15-24-27(29-34-28(23)24)21-8-4-3-5-9-21)33-19-6-18-32-22-13-10-20(11-14-22)12-17-26(30)31/h3-5,8-11,13-16H,2,6-7,12,17-19H2,1H3,(H,30,31)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
2n/an/an/an/an/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
In vitro binding affinity towards human peroxisome proliferator activated receptor delta (PPAR delta)


Bioorg Med Chem Lett 13: 931-5 (2003)


Article DOI: 10.1016/s0960-894x(02)01029-6
BindingDB Entry DOI: 10.7270/Q2HX1C1Z
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor


(Homo sapiens (human))
BDBM50124394
PNG
(2-Methyl-2-{4-[4-(3-phenyl-7-propyl-benzo[d]isoxaz...)
Show SMILES CCCc1c(OCCCCOc2ccc(OC(C)(C)C(O)=O)cc2)ccc2c(noc12)-c1ccccc1
Show InChI InChI=1S/C30H33NO6/c1-4-10-24-26(18-17-25-27(31-37-28(24)25)21-11-6-5-7-12-21)35-20-9-8-19-34-22-13-15-23(16-14-22)36-30(2,3)29(32)33/h5-7,11-18H,4,8-10,19-20H2,1-3H3,(H,32,33)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
2.40n/an/an/an/an/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
In vitro binding affinity towards human peroxisome proliferator activated receptor gamma (PPAR gamma)


Bioorg Med Chem Lett 13: 931-5 (2003)


Article DOI: 10.1016/s0960-894x(02)01029-6
BindingDB Entry DOI: 10.7270/Q2HX1C1Z
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha (PPAR alpha)


(Homo sapiens (Human))
BDBM50124379
PNG
(2-(4-(3-(3-phenyl-7-propylbenzo[d]isoxazol-6-yloxy...)
Show SMILES CCCc1c(OCCCOc2ccc(CC(O)=O)cc2)ccc2c(noc12)-c1ccccc1
Show InChI InChI=1S/C27H27NO5/c1-2-7-22-24(15-14-23-26(28-33-27(22)23)20-8-4-3-5-9-20)32-17-6-16-31-21-12-10-19(11-13-21)18-25(29)30/h3-5,8-15H,2,6-7,16-18H2,1H3,(H,29,30)
UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
3n/an/an/an/an/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
In vitro binding affinity towards human peroxisome proliferator activated receptor alpha (PPAR alpha)


Bioorg Med Chem Lett 13: 931-5 (2003)


Article DOI: 10.1016/s0960-894x(02)01029-6
BindingDB Entry DOI: 10.7270/Q2HX1C1Z
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor


(Homo sapiens (human))
BDBM33283
PNG
((3-{4-[(3-phenyl-7-propyl-1,2-benzisoxazol-6-yl)ox...)
Show SMILES CCCc1c(OCCCCOc2cccc(CC(O)=O)c2)ccc2c(noc12)-c1ccccc1
Show InChI InChI=1S/C28H29NO5/c1-2-9-23-25(15-14-24-27(29-34-28(23)24)21-11-4-3-5-12-21)33-17-7-6-16-32-22-13-8-10-20(18-22)19-26(30)31/h3-5,8,10-15,18H,2,6-7,9,16-17,19H2,1H3,(H,30,31)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
3.10n/an/an/an/an/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
In vitro binding affinity towards human peroxisome proliferator activated receptor alpha (PPAR alpha)


Bioorg Med Chem Lett 13: 931-5 (2003)


Article DOI: 10.1016/s0960-894x(02)01029-6
BindingDB Entry DOI: 10.7270/Q2HX1C1Z
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor delta (PPAR delta)


(Homo sapiens (Human))
BDBM50124369
PNG
(CHEMBL367019 | {3-Chloro-4-[3-(3-phenyl-7-propyl-b...)
Show SMILES CCCc1c(OCCCSc2ccc(CC(O)=O)cc2Cl)ccc2c(noc12)-c1ccccc1
Show InChI InChI=1S/C27H26ClNO4S/c1-2-7-20-23(12-11-21-26(29-33-27(20)21)19-8-4-3-5-9-19)32-14-6-15-34-24-13-10-18(16-22(24)28)17-25(30)31/h3-5,8-13,16H,2,6-7,14-15,17H2,1H3,(H,30,31)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
3.70n/an/an/an/an/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
In vitro binding affinity towards human peroxisome proliferator activated receptor delta (PPAR delta)


Bioorg Med Chem Lett 13: 931-5 (2003)


Article DOI: 10.1016/s0960-894x(02)01029-6
BindingDB Entry DOI: 10.7270/Q2HX1C1Z
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor


(Homo sapiens (Human))
BDBM50124384
PNG
(CHEMBL173494 | {4-[3-(3-Phenyl-7-propyl-benzo[d]is...)
Show SMILES CCCc1c(OCCCOc2ccc(OCC(O)=O)cc2)ccc2c(noc12)-c1ccccc1
Show InChI InChI=1S/C27H27NO6/c1-2-7-22-24(15-14-23-26(28-34-27(22)23)19-8-4-3-5-9-19)32-17-6-16-31-20-10-12-21(13-11-20)33-18-25(29)30/h3-5,8-15H,2,6-7,16-18H2,1H3,(H,29,30)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
3.70n/an/an/an/an/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Agonistic activity was determined in COS1 cells transfected with GAL 4-PPAR alpha receptor


Bioorg Med Chem Lett 13: 931-5 (2003)


Article DOI: 10.1016/s0960-894x(02)01029-6
BindingDB Entry DOI: 10.7270/Q2HX1C1Z
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor


(Homo sapiens (Human))
BDBM50124378
PNG
(2-{4-[3-(3-Phenyl-7-propyl-benzo[d]isoxazol-6-ylox...)
Show SMILES CCCc1c(OCCCOc2ccc(OC(C)C(O)=O)cc2)ccc2c(noc12)-c1ccccc1
Show InChI InChI=1S/C28H29NO6/c1-3-8-23-25(16-15-24-26(29-35-27(23)24)20-9-5-4-6-10-20)33-18-7-17-32-21-11-13-22(14-12-21)34-19(2)28(30)31/h4-6,9-16,19H,3,7-8,17-18H2,1-2H3,(H,30,31)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
4.60n/an/an/an/an/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Agonistic activity was determined in COS1 cells transfected with GAL 4-PPAR gamma receptor


Bioorg Med Chem Lett 13: 931-5 (2003)


Article DOI: 10.1016/s0960-894x(02)01029-6
BindingDB Entry DOI: 10.7270/Q2HX1C1Z
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor


(Homo sapiens (Human))
BDBM50124379
PNG
(2-(4-(3-(3-phenyl-7-propylbenzo[d]isoxazol-6-yloxy...)
Show SMILES CCCc1c(OCCCOc2ccc(CC(O)=O)cc2)ccc2c(noc12)-c1ccccc1
Show InChI InChI=1S/C27H27NO5/c1-2-7-22-24(15-14-23-26(28-33-27(22)23)20-8-4-3-5-9-20)32-17-6-16-31-21-12-10-19(11-13-21)18-25(29)30/h3-5,8-15H,2,6-7,16-18H2,1H3,(H,29,30)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
5n/an/an/an/an/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
In vitro binding affinity towards human peroxisome proliferator activated receptor alpha (PPAR alpha)


Bioorg Med Chem Lett 13: 931-5 (2003)


Article DOI: 10.1016/s0960-894x(02)01029-6
BindingDB Entry DOI: 10.7270/Q2HX1C1Z
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor


(Homo sapiens (Human))
BDBM50124385
PNG
(3-[4-(3-Phenyl-7-propyl-benzo[d]isoxazol-6-yloxy)-...)
Show SMILES CCCc1c(OCCCCOc2cccc(c2)C(O)=O)ccc2c(noc12)-c1ccccc1
Show InChI InChI=1S/C27H27NO5/c1-2-9-22-24(15-14-23-25(28-33-26(22)23)19-10-4-3-5-11-19)32-17-7-6-16-31-21-13-8-12-20(18-21)27(29)30/h3-5,8,10-15,18H,2,6-7,9,16-17H2,1H3,(H,29,30)
UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
5.20n/an/an/an/an/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Agonistic activity was determined in COS1 cells transfected with GAL 4-PPAR delta receptor


Bioorg Med Chem Lett 13: 931-5 (2003)


Article DOI: 10.1016/s0960-894x(02)01029-6
BindingDB Entry DOI: 10.7270/Q2HX1C1Z
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor


(Homo sapiens (Human))
BDBM50124386
PNG
(CHEMBL367311 | {4-[4-(3-Phenyl-7-propyl-benzo[d]is...)
Show SMILES CCCc1c(OCCCCOc2ccc(CC(O)=O)cc2)ccc2c(noc12)-c1ccccc1
Show InChI InChI=1S/C28H29NO5/c1-2-8-23-25(16-15-24-27(29-34-28(23)24)21-9-4-3-5-10-21)33-18-7-6-17-32-22-13-11-20(12-14-22)19-26(30)31/h3-5,9-16H,2,6-8,17-19H2,1H3,(H,30,31)
UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
7n/an/an/an/an/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Agonistic activity was determined in COS1 cells transfected with GAL 4-PPAR alpha receptor


Bioorg Med Chem Lett 13: 931-5 (2003)


Article DOI: 10.1016/s0960-894x(02)01029-6
BindingDB Entry DOI: 10.7270/Q2HX1C1Z
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor


(Homo sapiens (Human))
BDBM33283
PNG
((3-{4-[(3-phenyl-7-propyl-1,2-benzisoxazol-6-yl)ox...)
Show SMILES CCCc1c(OCCCCOc2cccc(CC(O)=O)c2)ccc2c(noc12)-c1ccccc1
Show InChI InChI=1S/C28H29NO5/c1-2-9-23-25(15-14-24-27(29-34-28(23)24)21-11-4-3-5-12-21)33-17-7-6-16-32-22-13-8-10-20(18-22)19-26(30)31/h3-5,8,10-15,18H,2,6-7,9,16-17,19H2,1H3,(H,30,31)
UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
7.20n/an/an/an/an/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
In vitro binding affinity towards human peroxisome proliferator activated receptor gamma (PPAR gamma)


Bioorg Med Chem Lett 13: 931-5 (2003)


Article DOI: 10.1016/s0960-894x(02)01029-6
BindingDB Entry DOI: 10.7270/Q2HX1C1Z
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha (PPAR alpha)


(Homo sapiens (Human))
BDBM50124377
PNG
(3-{4-[3-(3-Phenyl-7-propyl-benzo[d]isoxazol-6-ylox...)
Show SMILES CCCc1c(OCCCOc2ccc(CCC(O)=O)cc2)ccc2c(noc12)-c1ccccc1
Show InChI InChI=1S/C28H29NO5/c1-2-7-23-25(16-15-24-27(29-34-28(23)24)21-8-4-3-5-9-21)33-19-6-18-32-22-13-10-20(11-14-22)12-17-26(30)31/h3-5,8-11,13-16H,2,6-7,12,17-19H2,1H3,(H,30,31)
UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
7.30n/an/an/an/an/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
In vitro binding affinity towards human peroxisome proliferator activated receptor alpha (PPAR alpha)


Bioorg Med Chem Lett 13: 931-5 (2003)


Article DOI: 10.1016/s0960-894x(02)01029-6
BindingDB Entry DOI: 10.7270/Q2HX1C1Z
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha (PPAR alpha)


(Homo sapiens (Human))
BDBM50124374
PNG
(3-{4-[4-(3-Phenyl-7-propyl-benzo[d]isoxazol-6-ylox...)
Show SMILES CCCc1c(OCCCCOc2ccc(CCC(O)=O)cc2)ccc2c(noc12)-c1ccccc1
Show InChI InChI=1S/C29H31NO5/c1-2-8-24-26(17-16-25-28(30-35-29(24)25)22-9-4-3-5-10-22)34-20-7-6-19-33-23-14-11-21(12-15-23)13-18-27(31)32/h3-5,9-12,14-17H,2,6-8,13,18-20H2,1H3,(H,31,32)
UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
7.60n/an/an/an/an/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
In vitro binding affinity towards human peroxisome proliferator activated receptor alpha (PPAR alpha)


Bioorg Med Chem Lett 13: 931-5 (2003)


Article DOI: 10.1016/s0960-894x(02)01029-6
BindingDB Entry DOI: 10.7270/Q2HX1C1Z
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha (PPAR alpha)


(Homo sapiens (Human))
BDBM50124384
PNG
(CHEMBL173494 | {4-[3-(3-Phenyl-7-propyl-benzo[d]is...)
Show SMILES CCCc1c(OCCCOc2ccc(OCC(O)=O)cc2)ccc2c(noc12)-c1ccccc1
Show InChI InChI=1S/C27H27NO6/c1-2-7-22-24(15-14-23-26(28-34-27(22)23)19-8-4-3-5-9-19)32-17-6-16-31-20-10-12-21(13-11-20)33-18-25(29)30/h3-5,8-15H,2,6-7,16-18H2,1H3,(H,29,30)
UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
8.10n/an/an/an/an/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
In vitro binding affinity towards human peroxisome proliferator activated receptor alpha (PPAR alpha)


Bioorg Med Chem Lett 13: 931-5 (2003)


Article DOI: 10.1016/s0960-894x(02)01029-6
BindingDB Entry DOI: 10.7270/Q2HX1C1Z
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor


(Homo sapiens (human))
BDBM50124374
PNG
(3-{4-[4-(3-Phenyl-7-propyl-benzo[d]isoxazol-6-ylox...)
Show SMILES CCCc1c(OCCCCOc2ccc(CCC(O)=O)cc2)ccc2c(noc12)-c1ccccc1
Show InChI InChI=1S/C29H31NO5/c1-2-8-24-26(17-16-25-28(30-35-29(24)25)22-9-4-3-5-10-22)34-20-7-6-19-33-23-14-11-21(12-15-23)13-18-27(31)32/h3-5,9-12,14-17H,2,6-8,13,18-20H2,1H3,(H,31,32)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
8.90n/an/an/an/an/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
In vitro binding affinity towards human peroxisome proliferator activated receptor gamma (PPAR gamma)


Bioorg Med Chem Lett 13: 931-5 (2003)


Article DOI: 10.1016/s0960-894x(02)01029-6
BindingDB Entry DOI: 10.7270/Q2HX1C1Z
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha (PPAR alpha)


(Homo sapiens (Human))
BDBM50124378
PNG
(2-{4-[3-(3-Phenyl-7-propyl-benzo[d]isoxazol-6-ylox...)
Show SMILES CCCc1c(OCCCOc2ccc(OC(C)C(O)=O)cc2)ccc2c(noc12)-c1ccccc1
Show InChI InChI=1S/C28H29NO6/c1-3-8-23-25(16-15-24-26(29-35-27(23)24)20-9-5-4-6-10-20)33-18-7-17-32-21-11-13-22(14-12-21)34-19(2)28(30)31/h4-6,9-16,19H,3,7-8,17-18H2,1-2H3,(H,30,31)
UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
9.30n/an/an/an/an/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
In vitro binding affinity towards human peroxisome proliferator activated receptor alpha (PPAR alpha)


Bioorg Med Chem Lett 13: 931-5 (2003)


Article DOI: 10.1016/s0960-894x(02)01029-6
BindingDB Entry DOI: 10.7270/Q2HX1C1Z
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor


(Homo sapiens (human))
BDBM50124369
PNG
(CHEMBL367019 | {3-Chloro-4-[3-(3-phenyl-7-propyl-b...)
Show SMILES CCCc1c(OCCCSc2ccc(CC(O)=O)cc2Cl)ccc2c(noc12)-c1ccccc1
Show InChI InChI=1S/C27H26ClNO4S/c1-2-7-20-23(12-11-21-26(29-33-27(20)21)19-8-4-3-5-9-19)32-14-6-15-34-24-13-10-18(16-22(24)28)17-25(30)31/h3-5,8-13,16H,2,6-7,14-15,17H2,1H3,(H,30,31)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
11n/an/an/an/an/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
In vitro binding affinity towards human peroxisome proliferator activated receptor gamma (PPAR gamma)


Bioorg Med Chem Lett 13: 931-5 (2003)


Article DOI: 10.1016/s0960-894x(02)01029-6
BindingDB Entry DOI: 10.7270/Q2HX1C1Z
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha (PPAR alpha)


(Homo sapiens (Human))
BDBM50124383
PNG
(3-{4-[2-(3-Phenyl-7-propyl-benzo[d]isoxazol-6-ylox...)
Show SMILES CCCc1c(OCCOc2ccc(CCC(O)=O)cc2)ccc2c(noc12)-c1ccccc1
Show InChI InChI=1S/C27H27NO5/c1-2-6-22-24(15-14-23-26(28-33-27(22)23)20-7-4-3-5-8-20)32-18-17-31-21-12-9-19(10-13-21)11-16-25(29)30/h3-5,7-10,12-15H,2,6,11,16-18H2,1H3,(H,29,30)
UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
11n/an/an/an/an/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
In vitro binding affinity towards human peroxisome proliferator activated receptor alpha (PPAR alpha)


Bioorg Med Chem Lett 13: 931-5 (2003)


Article DOI: 10.1016/s0960-894x(02)01029-6
BindingDB Entry DOI: 10.7270/Q2HX1C1Z
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor delta (PPAR delta)


(Homo sapiens (Human))
BDBM50124383
PNG
(3-{4-[2-(3-Phenyl-7-propyl-benzo[d]isoxazol-6-ylox...)
Show SMILES CCCc1c(OCCOc2ccc(CCC(O)=O)cc2)ccc2c(noc12)-c1ccccc1
Show InChI InChI=1S/C27H27NO5/c1-2-6-22-24(15-14-23-26(28-33-27(22)23)20-7-4-3-5-8-20)32-18-17-31-21-12-9-19(10-13-21)11-16-25(29)30/h3-5,7-10,12-15H,2,6,11,16-18H2,1H3,(H,29,30)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
11n/an/an/an/an/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
In vitro binding affinity towards human peroxisome proliferator activated receptor delta (PPAR delta)


Bioorg Med Chem Lett 13: 931-5 (2003)


Article DOI: 10.1016/s0960-894x(02)01029-6
BindingDB Entry DOI: 10.7270/Q2HX1C1Z
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor


(Homo sapiens (human))
BDBM50124372
PNG
((E)-3-{4-[4-(3-Phenyl-7-propyl-benzo[d]isoxazol-6-...)
Show SMILES CCCc1c(OCCCCOc2ccc(\C=C\C(O)=O)cc2)ccc2c(noc12)-c1ccccc1
Show InChI InChI=1S/C29H29NO5/c1-2-8-24-26(17-16-25-28(30-35-29(24)25)22-9-4-3-5-10-22)34-20-7-6-19-33-23-14-11-21(12-15-23)13-18-27(31)32/h3-5,9-18H,2,6-8,19-20H2,1H3,(H,31,32)/b18-13+
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
13n/an/an/an/an/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Agonistic activity was determined in COS1 cells transfected with GAL 4-PPAR alpha receptor


Bioorg Med Chem Lett 13: 931-5 (2003)


Article DOI: 10.1016/s0960-894x(02)01029-6
BindingDB Entry DOI: 10.7270/Q2HX1C1Z
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha (PPAR alpha)


(Homo sapiens (Human))
BDBM50124389
PNG
(2,2-Dimethyl-3-{4-[4-(3-phenyl-7-propyl-benzo[d]is...)
Show SMILES CCCc1c(OCCCCOc2ccc(CC(C)(C)C(O)=O)cc2)ccc2c(noc12)-c1ccccc1
Show InChI InChI=1S/C31H35NO5/c1-4-10-25-27(18-17-26-28(32-37-29(25)26)23-11-6-5-7-12-23)36-20-9-8-19-35-24-15-13-22(14-16-24)21-31(2,3)30(33)34/h5-7,11-18H,4,8-10,19-21H2,1-3H3,(H,33,34)
UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
13n/an/an/an/an/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
In vitro binding affinity towards human peroxisome proliferator activated receptor alpha (PPAR alpha)


Bioorg Med Chem Lett 13: 931-5 (2003)


Article DOI: 10.1016/s0960-894x(02)01029-6
BindingDB Entry DOI: 10.7270/Q2HX1C1Z
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor


(Homo sapiens (Human))
BDBM50124369
PNG
(CHEMBL367019 | {3-Chloro-4-[3-(3-phenyl-7-propyl-b...)
Show SMILES CCCc1c(OCCCSc2ccc(CC(O)=O)cc2Cl)ccc2c(noc12)-c1ccccc1
Show InChI InChI=1S/C27H26ClNO4S/c1-2-7-20-23(12-11-21-26(29-33-27(20)21)19-8-4-3-5-9-19)32-14-6-15-34-24-13-10-18(16-22(24)28)17-25(30)31/h3-5,8-13,16H,2,6-7,14-15,17H2,1H3,(H,30,31)
UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
14n/an/an/an/an/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
In vitro binding affinity towards human peroxisome proliferator activated receptor alpha (PPAR alpha)


Bioorg Med Chem Lett 13: 931-5 (2003)


Article DOI: 10.1016/s0960-894x(02)01029-6
BindingDB Entry DOI: 10.7270/Q2HX1C1Z
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor


(Homo sapiens (Human))
BDBM50124394
PNG
(2-Methyl-2-{4-[4-(3-phenyl-7-propyl-benzo[d]isoxaz...)
Show SMILES CCCc1c(OCCCCOc2ccc(OC(C)(C)C(O)=O)cc2)ccc2c(noc12)-c1ccccc1
Show InChI InChI=1S/C30H33NO6/c1-4-10-24-26(18-17-25-27(31-37-28(24)25)21-11-6-5-7-12-21)35-20-9-8-19-34-22-13-15-23(16-14-22)36-30(2,3)29(32)33/h5-7,11-18H,4,8-10,19-20H2,1-3H3,(H,32,33)
UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
17n/an/an/an/an/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Agonistic activity was determined in COS1 cells transfected with GAL 4-PPAR alpha receptor


Bioorg Med Chem Lett 13: 931-5 (2003)


Article DOI: 10.1016/s0960-894x(02)01029-6
BindingDB Entry DOI: 10.7270/Q2HX1C1Z
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor


(Homo sapiens (human))
BDBM50124375
PNG
(2-Methyl-2-{4-[4-(3-phenyl-7-propyl-benzo[d]isoxaz...)
Show SMILES CCCc1c(OCCCCOc2ccc(cc2)C(C)(C)C(O)=O)ccc2c(noc12)-c1ccccc1
Show InChI InChI=1S/C30H33NO5/c1-4-10-24-26(18-17-25-27(31-36-28(24)25)21-11-6-5-7-12-21)35-20-9-8-19-34-23-15-13-22(14-16-23)30(2,3)29(32)33/h5-7,11-18H,4,8-10,19-20H2,1-3H3,(H,32,33)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
17n/an/an/an/an/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
In vitro binding affinity towards human peroxisome proliferator activated receptor gamma (PPAR gamma)


Bioorg Med Chem Lett 13: 931-5 (2003)


Article DOI: 10.1016/s0960-894x(02)01029-6
BindingDB Entry DOI: 10.7270/Q2HX1C1Z
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor


(Homo sapiens (Human))
BDBM50124372
PNG
((E)-3-{4-[4-(3-Phenyl-7-propyl-benzo[d]isoxazol-6-...)
Show SMILES CCCc1c(OCCCCOc2ccc(\C=C\C(O)=O)cc2)ccc2c(noc12)-c1ccccc1
Show InChI InChI=1S/C29H29NO5/c1-2-8-24-26(17-16-25-28(30-35-29(24)25)22-9-4-3-5-10-22)34-20-7-6-19-33-23-14-11-21(12-15-23)13-18-27(31)32/h3-5,9-18H,2,6-8,19-20H2,1H3,(H,31,32)/b18-13+
UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
18n/an/an/an/an/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Agonistic activity was determined in COS1 cells transfected with GAL 4-PPAR alpha receptor


Bioorg Med Chem Lett 13: 931-5 (2003)


Article DOI: 10.1016/s0960-894x(02)01029-6
BindingDB Entry DOI: 10.7270/Q2HX1C1Z
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor delta (PPAR delta)


(Homo sapiens (Human))
BDBM50124371
PNG
((E)-3-{4-[3-(3-Phenyl-7-propyl-benzo[d]isoxazol-6-...)
Show SMILES CCCc1c(OCCCOc2ccc(\C=C\C(O)=O)cc2)ccc2c(noc12)-c1ccccc1
Show InChI InChI=1S/C28H27NO5/c1-2-7-23-25(16-15-24-27(29-34-28(23)24)21-8-4-3-5-9-21)33-19-6-18-32-22-13-10-20(11-14-22)12-17-26(30)31/h3-5,8-17H,2,6-7,18-19H2,1H3,(H,30,31)/b17-12+
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
18n/an/an/an/an/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
In vitro binding affinity towards human peroxisome proliferator activated receptor delta (PPAR delta)


Bioorg Med Chem Lett 13: 931-5 (2003)


Article DOI: 10.1016/s0960-894x(02)01029-6
BindingDB Entry DOI: 10.7270/Q2HX1C1Z
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor


(Homo sapiens (human))
BDBM50124392
PNG
(2-{4-[4-(3-Phenyl-7-propyl-benzo[d]isoxazol-6-ylox...)
Show SMILES CCCc1c(OCCCCOc2ccc(OC(C)C(O)=O)cc2)ccc2c(noc12)-c1ccccc1
Show InChI InChI=1S/C29H31NO6/c1-3-9-24-26(17-16-25-27(30-36-28(24)25)21-10-5-4-6-11-21)34-19-8-7-18-33-22-12-14-23(15-13-22)35-20(2)29(31)32/h4-6,10-17,20H,3,7-9,18-19H2,1-2H3,(H,31,32)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
20n/an/an/an/an/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Agonistic activity was determined in COS1 cells transfected with GAL 4-PPAR delta receptor


Bioorg Med Chem Lett 13: 931-5 (2003)


Article DOI: 10.1016/s0960-894x(02)01029-6
BindingDB Entry DOI: 10.7270/Q2HX1C1Z
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor


(Homo sapiens (human))
BDBM50124389
PNG
(2,2-Dimethyl-3-{4-[4-(3-phenyl-7-propyl-benzo[d]is...)
Show SMILES CCCc1c(OCCCCOc2ccc(CC(C)(C)C(O)=O)cc2)ccc2c(noc12)-c1ccccc1
Show InChI InChI=1S/C31H35NO5/c1-4-10-25-27(18-17-26-28(32-37-29(25)26)23-11-6-5-7-12-23)36-20-9-8-19-35-24-15-13-22(14-16-24)21-31(2,3)30(33)34/h5-7,11-18H,4,8-10,19-21H2,1-3H3,(H,33,34)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
20n/an/an/an/an/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
In vitro binding affinity towards human peroxisome proliferator activated receptor gamma (PPAR gamma)


Bioorg Med Chem Lett 13: 931-5 (2003)


Article DOI: 10.1016/s0960-894x(02)01029-6
BindingDB Entry DOI: 10.7270/Q2HX1C1Z
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor delta (PPAR delta)


(Homo sapiens (Human))
BDBM50124388
PNG
(3-{3-[3-(3-Phenyl-7-propyl-benzo[d]isoxazol-6-ylox...)
Show SMILES CCCc1c(OCCCOc2cccc(CCC(O)=O)c2)ccc2c(noc12)-c1ccccc1
Show InChI InChI=1S/C28H29NO5/c1-2-8-23-25(15-14-24-27(29-34-28(23)24)21-10-4-3-5-11-21)33-18-7-17-32-22-12-6-9-20(19-22)13-16-26(30)31/h3-6,9-12,14-15,19H,2,7-8,13,16-18H2,1H3,(H,30,31)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
21n/an/an/an/an/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
In vitro binding affinity towards human peroxisome proliferator activated receptor delta (PPAR delta)


Bioorg Med Chem Lett 13: 931-5 (2003)


Article DOI: 10.1016/s0960-894x(02)01029-6
BindingDB Entry DOI: 10.7270/Q2HX1C1Z
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor


(Homo sapiens (human))
BDBM50124378
PNG
(2-{4-[3-(3-Phenyl-7-propyl-benzo[d]isoxazol-6-ylox...)
Show SMILES CCCc1c(OCCCOc2ccc(OC(C)C(O)=O)cc2)ccc2c(noc12)-c1ccccc1
Show InChI InChI=1S/C28H29NO6/c1-3-8-23-25(16-15-24-26(29-35-27(23)24)20-9-5-4-6-10-20)33-18-7-17-32-21-11-13-22(14-12-21)34-19(2)28(30)31/h4-6,9-16,19H,3,7-8,17-18H2,1-2H3,(H,30,31)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
22n/an/an/an/an/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
In vitro binding affinity towards human peroxisome proliferator activated receptor gamma (PPAR gamma)


Bioorg Med Chem Lett 13: 931-5 (2003)


Article DOI: 10.1016/s0960-894x(02)01029-6
BindingDB Entry DOI: 10.7270/Q2HX1C1Z
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha (PPAR alpha)


(Homo sapiens (Human))
BDBM50124375
PNG
(2-Methyl-2-{4-[4-(3-phenyl-7-propyl-benzo[d]isoxaz...)
Show SMILES CCCc1c(OCCCCOc2ccc(cc2)C(C)(C)C(O)=O)ccc2c(noc12)-c1ccccc1
Show InChI InChI=1S/C30H33NO5/c1-4-10-24-26(18-17-25-27(31-36-28(24)25)21-11-6-5-7-12-21)35-20-9-8-19-34-23-15-13-22(14-16-23)30(2,3)29(32)33/h5-7,11-18H,4,8-10,19-20H2,1-3H3,(H,32,33)
UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
23n/an/an/an/an/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
In vitro binding affinity towards human peroxisome proliferator activated receptor alpha (PPAR alpha)


Bioorg Med Chem Lett 13: 931-5 (2003)


Article DOI: 10.1016/s0960-894x(02)01029-6
BindingDB Entry DOI: 10.7270/Q2HX1C1Z
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor


(Homo sapiens (Human))
BDBM50124394
PNG
(2-Methyl-2-{4-[4-(3-phenyl-7-propyl-benzo[d]isoxaz...)
Show SMILES CCCc1c(OCCCCOc2ccc(OC(C)(C)C(O)=O)cc2)ccc2c(noc12)-c1ccccc1
Show InChI InChI=1S/C30H33NO6/c1-4-10-24-26(18-17-25-27(31-37-28(24)25)21-11-6-5-7-12-21)35-20-9-8-19-34-22-13-15-23(16-14-22)36-30(2,3)29(32)33/h5-7,11-18H,4,8-10,19-20H2,1-3H3,(H,32,33)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
23n/an/an/an/an/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Agonistic activity was determined in COS1 cells transfected with GAL 4-PPAR delta receptor


Bioorg Med Chem Lett 13: 931-5 (2003)


Article DOI: 10.1016/s0960-894x(02)01029-6
BindingDB Entry DOI: 10.7270/Q2HX1C1Z
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor


(Homo sapiens (human))
BDBM50124387
PNG
(2-Methyl-2-{3-[4-(3-phenyl-7-propyl-benzo[d]isoxaz...)
Show SMILES CCCc1c(OCCCCOc2cccc(c2)C(C)(C)C(O)=O)ccc2c(noc12)-c1ccccc1
Show InChI InChI=1S/C30H33NO5/c1-4-11-24-26(17-16-25-27(31-36-28(24)25)21-12-6-5-7-13-21)35-19-9-8-18-34-23-15-10-14-22(20-23)30(2,3)29(32)33/h5-7,10,12-17,20H,4,8-9,11,18-19H2,1-3H3,(H,32,33)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
26n/an/an/an/an/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
In vitro binding affinity towards human peroxisome proliferator activated receptor gamma (PPAR gamma)


Bioorg Med Chem Lett 13: 931-5 (2003)


Article DOI: 10.1016/s0960-894x(02)01029-6
BindingDB Entry DOI: 10.7270/Q2HX1C1Z
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor delta (PPAR delta)


(Homo sapiens (Human))
BDBM50124381
PNG
(CHEMBL172718 | {3-[3-(3-Phenyl-7-propyl-benzo[d]is...)
Show SMILES CCCc1c(OCCCOc2cccc(CC(O)=O)c2)ccc2c(noc12)-c1ccccc1
Show InChI InChI=1S/C27H27NO5/c1-2-8-22-24(14-13-23-26(28-33-27(22)23)20-10-4-3-5-11-20)32-16-7-15-31-21-12-6-9-19(17-21)18-25(29)30/h3-6,9-14,17H,2,7-8,15-16,18H2,1H3,(H,29,30)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
26n/an/an/an/an/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
In vitro binding affinity towards human peroxisome proliferator activated receptor delta (PPAR delta)


Bioorg Med Chem Lett 13: 931-5 (2003)


Article DOI: 10.1016/s0960-894x(02)01029-6
BindingDB Entry DOI: 10.7270/Q2HX1C1Z
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor


(Homo sapiens (human))
BDBM50124386
PNG
(CHEMBL367311 | {4-[4-(3-Phenyl-7-propyl-benzo[d]is...)
Show SMILES CCCc1c(OCCCCOc2ccc(CC(O)=O)cc2)ccc2c(noc12)-c1ccccc1
Show InChI InChI=1S/C28H29NO5/c1-2-8-23-25(16-15-24-27(29-34-28(23)24)21-9-4-3-5-10-21)33-18-7-6-17-32-22-13-11-20(12-14-22)19-26(30)31/h3-5,9-16H,2,6-8,17-19H2,1H3,(H,30,31)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
30n/an/an/an/an/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Agonistic activity was determined in COS1 cells transfected with GAL 4-PPAR delta receptor


Bioorg Med Chem Lett 13: 931-5 (2003)


Article DOI: 10.1016/s0960-894x(02)01029-6
BindingDB Entry DOI: 10.7270/Q2HX1C1Z
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor


(Homo sapiens (human))
BDBM50124377
PNG
(3-{4-[3-(3-Phenyl-7-propyl-benzo[d]isoxazol-6-ylox...)
Show SMILES CCCc1c(OCCCOc2ccc(CCC(O)=O)cc2)ccc2c(noc12)-c1ccccc1
Show InChI InChI=1S/C28H29NO5/c1-2-7-23-25(16-15-24-27(29-34-28(23)24)21-8-4-3-5-9-21)33-19-6-18-32-22-13-10-20(11-14-22)12-17-26(30)31/h3-5,8-11,13-16H,2,6-7,12,17-19H2,1H3,(H,30,31)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
32n/an/an/an/an/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
In vitro binding affinity towards human peroxisome proliferator activated receptor gamma (PPAR gamma)


Bioorg Med Chem Lett 13: 931-5 (2003)


Article DOI: 10.1016/s0960-894x(02)01029-6
BindingDB Entry DOI: 10.7270/Q2HX1C1Z
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor


(Homo sapiens (human))
BDBM50124379
PNG
(2-(4-(3-(3-phenyl-7-propylbenzo[d]isoxazol-6-yloxy...)
Show SMILES CCCc1c(OCCCOc2ccc(CC(O)=O)cc2)ccc2c(noc12)-c1ccccc1
Show InChI InChI=1S/C27H27NO5/c1-2-7-22-24(15-14-23-26(28-33-27(22)23)20-8-4-3-5-9-20)32-17-6-16-31-21-12-10-19(11-13-21)18-25(29)30/h3-5,8-15H,2,6-7,16-18H2,1H3,(H,29,30)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
32n/an/an/an/an/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
In vitro binding affinity towards human peroxisome proliferator activated receptor gamma (PPAR gamma)


Bioorg Med Chem Lett 13: 931-5 (2003)


Article DOI: 10.1016/s0960-894x(02)01029-6
BindingDB Entry DOI: 10.7270/Q2HX1C1Z
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor


(Homo sapiens (human))
BDBM50124384
PNG
(CHEMBL173494 | {4-[3-(3-Phenyl-7-propyl-benzo[d]is...)
Show SMILES CCCc1c(OCCCOc2ccc(OCC(O)=O)cc2)ccc2c(noc12)-c1ccccc1
Show InChI InChI=1S/C27H27NO6/c1-2-7-22-24(15-14-23-26(28-34-27(22)23)19-8-4-3-5-9-19)32-17-6-16-31-20-10-12-21(13-11-20)33-18-25(29)30/h3-5,8-15H,2,6-7,16-18H2,1H3,(H,29,30)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
34n/an/an/an/an/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
In vitro binding affinity towards human peroxisome proliferator activated receptor gamma (PPAR gamma)


Bioorg Med Chem Lett 13: 931-5 (2003)


Article DOI: 10.1016/s0960-894x(02)01029-6
BindingDB Entry DOI: 10.7270/Q2HX1C1Z
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor delta (PPAR delta)


(Homo sapiens (Human))
BDBM50124376
PNG
(4-{4-[3-(3-Phenyl-7-propyl-benzo[d]isoxazol-6-ylox...)
Show SMILES CCCc1c(OCCCOc2ccc(CCCC(O)=O)cc2)ccc2c(noc12)-c1ccccc1
Show InChI InChI=1S/C29H31NO5/c1-2-8-24-26(18-17-25-28(30-35-29(24)25)22-10-4-3-5-11-22)34-20-7-19-33-23-15-13-21(14-16-23)9-6-12-27(31)32/h3-5,10-11,13-18H,2,6-9,12,19-20H2,1H3,(H,31,32)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
38n/an/an/an/an/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
In vitro binding affinity towards human peroxisome proliferator activated receptor delta (PPAR delta)


Bioorg Med Chem Lett 13: 931-5 (2003)


Article DOI: 10.1016/s0960-894x(02)01029-6
BindingDB Entry DOI: 10.7270/Q2HX1C1Z
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor delta (PPAR delta)


(Homo sapiens (Human))
BDBM50124374
PNG
(3-{4-[4-(3-Phenyl-7-propyl-benzo[d]isoxazol-6-ylox...)
Show SMILES CCCc1c(OCCCCOc2ccc(CCC(O)=O)cc2)ccc2c(noc12)-c1ccccc1
Show InChI InChI=1S/C29H31NO5/c1-2-8-24-26(17-16-25-28(30-35-29(24)25)22-9-4-3-5-10-22)34-20-7-6-19-33-23-14-11-21(12-15-23)13-18-27(31)32/h3-5,9-12,14-17H,2,6-8,13,18-20H2,1H3,(H,31,32)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
38n/an/an/an/an/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
In vitro binding affinity towards human peroxisome proliferator activated receptor delta (PPAR delta)


Bioorg Med Chem Lett 13: 931-5 (2003)


Article DOI: 10.1016/s0960-894x(02)01029-6
BindingDB Entry DOI: 10.7270/Q2HX1C1Z
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor


(Homo sapiens (human))
BDBM50124380
PNG
(2-Methyl-2-{3-[4-(3-phenyl-7-propyl-benzo[d]isoxaz...)
Show SMILES CCCc1c(OCCCCOc2cccc(OC(C)(C)C(O)=O)c2)ccc2c(noc12)-c1ccccc1
Show InChI InChI=1S/C30H33NO6/c1-4-11-24-26(17-16-25-27(31-37-28(24)25)21-12-6-5-7-13-21)35-19-9-8-18-34-22-14-10-15-23(20-22)36-30(2,3)29(32)33/h5-7,10,12-17,20H,4,8-9,11,18-19H2,1-3H3,(H,32,33)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
41n/an/an/an/an/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
In vitro binding affinity towards human peroxisome proliferator activated receptor gamma (PPAR gamma)


Bioorg Med Chem Lett 13: 931-5 (2003)


Article DOI: 10.1016/s0960-894x(02)01029-6
BindingDB Entry DOI: 10.7270/Q2HX1C1Z
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha (PPAR alpha)


(Homo sapiens (Human))
BDBM50124387
PNG
(2-Methyl-2-{3-[4-(3-phenyl-7-propyl-benzo[d]isoxaz...)
Show SMILES CCCc1c(OCCCCOc2cccc(c2)C(C)(C)C(O)=O)ccc2c(noc12)-c1ccccc1
Show InChI InChI=1S/C30H33NO5/c1-4-11-24-26(17-16-25-27(31-36-28(24)25)21-12-6-5-7-13-21)35-19-9-8-18-34-23-15-10-14-22(20-23)30(2,3)29(32)33/h5-7,10,12-17,20H,4,8-9,11,18-19H2,1-3H3,(H,32,33)
UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
46n/an/an/an/an/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
In vitro binding affinity towards human peroxisome proliferator activated receptor alpha (PPAR alpha)


Bioorg Med Chem Lett 13: 931-5 (2003)


Article DOI: 10.1016/s0960-894x(02)01029-6
BindingDB Entry DOI: 10.7270/Q2HX1C1Z
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor delta (PPAR delta)


(Homo sapiens (Human))
BDBM50124370
PNG
(CHEMBL173409 | {3-[4-(3-Phenyl-7-propyl-benzo[d]is...)
Show SMILES CCCc1c(OCCCCOc2cccc(OCC(O)=O)c2)ccc2c(noc12)-c1ccccc1
Show InChI InChI=1S/C28H29NO6/c1-2-9-23-25(15-14-24-27(29-35-28(23)24)20-10-4-3-5-11-20)33-17-7-6-16-32-21-12-8-13-22(18-21)34-19-26(30)31/h3-5,8,10-15,18H,2,6-7,9,16-17,19H2,1H3,(H,30,31)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
47n/an/an/an/an/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
In vitro binding affinity towards human peroxisome proliferator activated receptor delta (PPAR delta)


Bioorg Med Chem Lett 13: 931-5 (2003)


Article DOI: 10.1016/s0960-894x(02)01029-6
BindingDB Entry DOI: 10.7270/Q2HX1C1Z
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor


(Homo sapiens (Human))
BDBM50124392
PNG
(2-{4-[4-(3-Phenyl-7-propyl-benzo[d]isoxazol-6-ylox...)
Show SMILES CCCc1c(OCCCCOc2ccc(OC(C)C(O)=O)cc2)ccc2c(noc12)-c1ccccc1
Show InChI InChI=1S/C29H31NO6/c1-3-9-24-26(17-16-25-27(30-36-28(24)25)21-10-5-4-6-11-21)34-19-8-7-18-33-22-12-14-23(15-13-22)35-20(2)29(31)32/h4-6,10-17,20H,3,7-9,18-19H2,1-2H3,(H,31,32)
UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
47n/an/an/an/an/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
In vitro binding affinity towards human peroxisome proliferator activated receptor alpha (PPAR alpha)


Bioorg Med Chem Lett 13: 931-5 (2003)


Article DOI: 10.1016/s0960-894x(02)01029-6
BindingDB Entry DOI: 10.7270/Q2HX1C1Z
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor delta (PPAR delta)


(Homo sapiens (Human))
BDBM50124391
PNG
(CHEMBL176421 | {2-[4-(3-Phenyl-7-propyl-benzo[d]is...)
Show SMILES CCCc1c(OCCCCOc2ccccc2CC(O)=O)ccc2c(noc12)-c1ccccc1
Show InChI InChI=1S/C28H29NO5/c1-2-10-22-25(16-15-23-27(29-34-28(22)23)20-11-4-3-5-12-20)33-18-9-8-17-32-24-14-7-6-13-21(24)19-26(30)31/h3-7,11-16H,2,8-10,17-19H2,1H3,(H,30,31)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
47n/an/an/an/an/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
In vitro binding affinity towards human peroxisome proliferator activated receptor delta (PPAR delta)


Bioorg Med Chem Lett 13: 931-5 (2003)


Article DOI: 10.1016/s0960-894x(02)01029-6
BindingDB Entry DOI: 10.7270/Q2HX1C1Z
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha (PPAR alpha)


(Homo sapiens (Human))
BDBM50124371
PNG
((E)-3-{4-[3-(3-Phenyl-7-propyl-benzo[d]isoxazol-6-...)
Show SMILES CCCc1c(OCCCOc2ccc(\C=C\C(O)=O)cc2)ccc2c(noc12)-c1ccccc1
Show InChI InChI=1S/C28H27NO5/c1-2-7-23-25(16-15-24-27(29-34-28(23)24)21-8-4-3-5-9-21)33-19-6-18-32-22-13-10-20(11-14-22)12-17-26(30)31/h3-5,8-17H,2,6-7,18-19H2,1H3,(H,30,31)/b17-12+
UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
50n/an/an/an/an/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
In vitro binding affinity towards human peroxisome proliferator activated receptor alpha (PPAR alpha)


Bioorg Med Chem Lett 13: 931-5 (2003)


Article DOI: 10.1016/s0960-894x(02)01029-6
BindingDB Entry DOI: 10.7270/Q2HX1C1Z
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor


(Homo sapiens (human))
BDBM50124382
PNG
(3-Methyl-3-{4-[4-(3-phenyl-7-propyl-benzo[d]isoxaz...)
Show SMILES CCCc1c(OCCCCOc2ccc(cc2)C(C)(C)CC(O)=O)ccc2c(noc12)-c1ccccc1
Show InChI InChI=1S/C31H35NO5/c1-4-10-25-27(18-17-26-29(32-37-30(25)26)22-11-6-5-7-12-22)36-20-9-8-19-35-24-15-13-23(14-16-24)31(2,3)21-28(33)34/h5-7,11-18H,4,8-10,19-21H2,1-3H3,(H,33,34)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
52n/an/an/an/an/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
In vitro binding affinity towards human peroxisome proliferator activated receptor gamma (PPAR gamma)


Bioorg Med Chem Lett 13: 931-5 (2003)


Article DOI: 10.1016/s0960-894x(02)01029-6
BindingDB Entry DOI: 10.7270/Q2HX1C1Z
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor delta (PPAR delta)


(Homo sapiens (Human))
BDBM50124368
PNG
(3-{3-[4-(3-Phenyl-7-propyl-benzo[d]isoxazol-6-ylox...)
Show SMILES CCCc1c(OCCCCOc2cccc(CCC(O)=O)c2)ccc2c(noc12)-c1ccccc1
Show InChI InChI=1S/C29H31NO5/c1-2-9-24-26(16-15-25-28(30-35-29(24)25)22-11-4-3-5-12-22)34-19-7-6-18-33-23-13-8-10-21(20-23)14-17-27(31)32/h3-5,8,10-13,15-16,20H,2,6-7,9,14,17-19H2,1H3,(H,31,32)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
52n/an/an/an/an/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
In vitro binding affinity towards human peroxisome proliferator activated receptor delta (PPAR delta)


Bioorg Med Chem Lett 13: 931-5 (2003)


Article DOI: 10.1016/s0960-894x(02)01029-6
BindingDB Entry DOI: 10.7270/Q2HX1C1Z
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor


(Homo sapiens (human))
BDBM50124370
PNG
(CHEMBL173409 | {3-[4-(3-Phenyl-7-propyl-benzo[d]is...)
Show SMILES CCCc1c(OCCCCOc2cccc(OCC(O)=O)c2)ccc2c(noc12)-c1ccccc1
Show InChI InChI=1S/C28H29NO6/c1-2-9-23-25(15-14-24-27(29-35-28(23)24)20-10-4-3-5-11-20)33-17-7-6-16-32-21-12-8-13-22(18-21)34-19-26(30)31/h3-5,8,10-15,18H,2,6-7,9,16-17,19H2,1H3,(H,30,31)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
52n/an/an/an/an/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
In vitro binding affinity towards human peroxisome proliferator activated receptor gamma (PPAR gamma)


Bioorg Med Chem Lett 13: 931-5 (2003)


Article DOI: 10.1016/s0960-894x(02)01029-6
BindingDB Entry DOI: 10.7270/Q2HX1C1Z
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha (PPAR alpha)


(Homo sapiens (Human))
BDBM50124388
PNG
(3-{3-[3-(3-Phenyl-7-propyl-benzo[d]isoxazol-6-ylox...)
Show SMILES CCCc1c(OCCCOc2cccc(CCC(O)=O)c2)ccc2c(noc12)-c1ccccc1
Show InChI InChI=1S/C28H29NO5/c1-2-8-23-25(15-14-24-27(29-34-28(23)24)21-10-4-3-5-11-21)33-18-7-17-32-22-12-6-9-20(19-22)13-16-26(30)31/h3-6,9-12,14-15,19H,2,7-8,13,16-18H2,1H3,(H,30,31)
UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
53n/an/an/an/an/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
In vitro binding affinity towards human peroxisome proliferator activated receptor alpha (PPAR alpha)


Bioorg Med Chem Lett 13: 931-5 (2003)


Article DOI: 10.1016/s0960-894x(02)01029-6
BindingDB Entry DOI: 10.7270/Q2HX1C1Z
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor delta (PPAR delta)


(Homo sapiens (Human))
BDBM50124390
PNG
(CHEMBL175213 | {2-[3-(3-Phenyl-7-propyl-benzo[d]is...)
Show SMILES CCCc1c(OCCCOc2ccccc2CC(O)=O)ccc2c(noc12)-c1ccccc1
Show InChI InChI=1S/C27H27NO5/c1-2-9-21-24(15-14-22-26(28-33-27(21)22)19-10-4-3-5-11-19)32-17-8-16-31-23-13-7-6-12-20(23)18-25(29)30/h3-7,10-15H,2,8-9,16-18H2,1H3,(H,29,30)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
62n/an/an/an/an/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
In vitro binding affinity towards human peroxisome proliferator activated receptor delta (PPAR delta)


Bioorg Med Chem Lett 13: 931-5 (2003)


Article DOI: 10.1016/s0960-894x(02)01029-6
BindingDB Entry DOI: 10.7270/Q2HX1C1Z
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha (PPAR alpha)


(Homo sapiens (Human))
BDBM50124381
PNG
(CHEMBL172718 | {3-[3-(3-Phenyl-7-propyl-benzo[d]is...)
Show SMILES CCCc1c(OCCCOc2cccc(CC(O)=O)c2)ccc2c(noc12)-c1ccccc1
Show InChI InChI=1S/C27H27NO5/c1-2-8-22-24(14-13-23-26(28-33-27(22)23)20-10-4-3-5-11-20)32-16-7-15-31-21-12-6-9-19(17-21)18-25(29)30/h3-6,9-14,17H,2,7-8,15-16,18H2,1H3,(H,29,30)
UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
76n/an/an/an/an/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
In vitro binding affinity towards human peroxisome proliferator activated receptor alpha (PPAR alpha)


Bioorg Med Chem Lett 13: 931-5 (2003)


Article DOI: 10.1016/s0960-894x(02)01029-6
BindingDB Entry DOI: 10.7270/Q2HX1C1Z
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha (PPAR alpha)


(Homo sapiens (Human))
BDBM50124391
PNG
(CHEMBL176421 | {2-[4-(3-Phenyl-7-propyl-benzo[d]is...)
Show SMILES CCCc1c(OCCCCOc2ccccc2CC(O)=O)ccc2c(noc12)-c1ccccc1
Show InChI InChI=1S/C28H29NO5/c1-2-10-22-25(16-15-23-27(29-34-28(22)23)20-11-4-3-5-12-20)33-18-9-8-17-32-24-14-7-6-13-21(24)19-26(30)31/h3-7,11-16H,2,8-10,17-19H2,1H3,(H,30,31)
UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
86n/an/an/an/an/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
In vitro binding affinity towards human peroxisome proliferator activated receptor alpha (PPAR alpha)


Bioorg Med Chem Lett 13: 931-5 (2003)


Article DOI: 10.1016/s0960-894x(02)01029-6
BindingDB Entry DOI: 10.7270/Q2HX1C1Z
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor delta (PPAR delta)


(Homo sapiens (Human))
BDBM50124386
PNG
(CHEMBL367311 | {4-[4-(3-Phenyl-7-propyl-benzo[d]is...)
Show SMILES CCCc1c(OCCCCOc2ccc(CC(O)=O)cc2)ccc2c(noc12)-c1ccccc1
Show InChI InChI=1S/C28H29NO5/c1-2-8-23-25(16-15-24-27(29-34-28(23)24)21-9-4-3-5-10-21)33-18-7-6-17-32-22-13-11-20(12-14-22)19-26(30)31/h3-5,9-16H,2,6-8,17-19H2,1H3,(H,30,31)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
93n/an/an/an/an/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
In vitro binding affinity towards human peroxisome proliferator activated receptor delta (PPAR delta)


Bioorg Med Chem Lett 13: 931-5 (2003)


Article DOI: 10.1016/s0960-894x(02)01029-6
BindingDB Entry DOI: 10.7270/Q2HX1C1Z
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor


(Homo sapiens (human))
BDBM50124385
PNG
(3-[4-(3-Phenyl-7-propyl-benzo[d]isoxazol-6-yloxy)-...)
Show SMILES CCCc1c(OCCCCOc2cccc(c2)C(O)=O)ccc2c(noc12)-c1ccccc1
Show InChI InChI=1S/C27H27NO5/c1-2-9-22-24(15-14-23-25(28-33-26(22)23)19-10-4-3-5-11-19)32-17-7-6-16-31-21-13-8-12-20(18-21)27(29)30/h3-5,8,10-15,18H,2,6-7,9,16-17H2,1H3,(H,29,30)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
100n/an/an/an/an/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Agonistic activity was determined in COS1 cells transfected with GAL 4-PPAR gamma receptor


Bioorg Med Chem Lett 13: 931-5 (2003)


Article DOI: 10.1016/s0960-894x(02)01029-6
BindingDB Entry DOI: 10.7270/Q2HX1C1Z
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor delta (PPAR delta)


(Homo sapiens (Human))
BDBM50124380
PNG
(2-Methyl-2-{3-[4-(3-phenyl-7-propyl-benzo[d]isoxaz...)
Show SMILES CCCc1c(OCCCCOc2cccc(OC(C)(C)C(O)=O)c2)ccc2c(noc12)-c1ccccc1
Show InChI InChI=1S/C30H33NO6/c1-4-11-24-26(17-16-25-27(31-37-28(24)25)21-12-6-5-7-13-21)35-19-9-8-18-34-22-14-10-15-23(20-22)36-30(2,3)29(32)33/h5-7,10,12-17,20H,4,8-9,11,18-19H2,1-3H3,(H,32,33)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
110n/an/an/an/an/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
In vitro binding affinity towards human peroxisome proliferator activated receptor delta (PPAR delta)


Bioorg Med Chem Lett 13: 931-5 (2003)


Article DOI: 10.1016/s0960-894x(02)01029-6
BindingDB Entry DOI: 10.7270/Q2HX1C1Z
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor


(Homo sapiens (human))
BDBM50124368
PNG
(3-{3-[4-(3-Phenyl-7-propyl-benzo[d]isoxazol-6-ylox...)
Show SMILES CCCc1c(OCCCCOc2cccc(CCC(O)=O)c2)ccc2c(noc12)-c1ccccc1
Show InChI InChI=1S/C29H31NO5/c1-2-9-24-26(16-15-25-28(30-35-29(24)25)22-11-4-3-5-12-22)34-19-7-6-18-33-23-13-8-10-21(20-23)14-17-27(31)32/h3-5,8,10-13,15-16,20H,2,6-7,9,14,17-19H2,1H3,(H,31,32)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
115n/an/an/an/an/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
In vitro binding affinity towards human peroxisome proliferator activated receptor gamma (PPAR gamma)


Bioorg Med Chem Lett 13: 931-5 (2003)


Article DOI: 10.1016/s0960-894x(02)01029-6
BindingDB Entry DOI: 10.7270/Q2HX1C1Z
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor


(Homo sapiens (Human))
BDBM50124376
PNG
(4-{4-[3-(3-Phenyl-7-propyl-benzo[d]isoxazol-6-ylox...)
Show SMILES CCCc1c(OCCCOc2ccc(CCCC(O)=O)cc2)ccc2c(noc12)-c1ccccc1
Show InChI InChI=1S/C29H31NO5/c1-2-8-24-26(18-17-25-28(30-35-29(24)25)22-10-4-3-5-11-22)34-20-7-19-33-23-15-13-21(14-16-23)9-6-12-27(31)32/h3-5,10-11,13-18H,2,6-9,12,19-20H2,1H3,(H,31,32)
UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
121n/an/an/an/an/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Agonistic activity was determined in COS1 cells transfected with GAL 4-PPAR alpha receptor


Bioorg Med Chem Lett 13: 931-5 (2003)


Article DOI: 10.1016/s0960-894x(02)01029-6
BindingDB Entry DOI: 10.7270/Q2HX1C1Z
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha (PPAR alpha)


(Homo sapiens (Human))
BDBM50124370
PNG
(CHEMBL173409 | {3-[4-(3-Phenyl-7-propyl-benzo[d]is...)
Show SMILES CCCc1c(OCCCCOc2cccc(OCC(O)=O)c2)ccc2c(noc12)-c1ccccc1
Show InChI InChI=1S/C28H29NO6/c1-2-9-23-25(15-14-24-27(29-35-28(23)24)20-10-4-3-5-11-20)33-17-7-6-16-32-21-12-8-13-22(18-21)34-19-26(30)31/h3-5,8,10-15,18H,2,6-7,9,16-17,19H2,1H3,(H,30,31)
UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
133n/an/an/an/an/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
In vitro binding affinity towards human peroxisome proliferator activated receptor alpha (PPAR alpha)


Bioorg Med Chem Lett 13: 931-5 (2003)


Article DOI: 10.1016/s0960-894x(02)01029-6
BindingDB Entry DOI: 10.7270/Q2HX1C1Z
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor delta (PPAR delta)


(Homo sapiens (Human))
BDBM50124392
PNG
(2-{4-[4-(3-Phenyl-7-propyl-benzo[d]isoxazol-6-ylox...)
Show SMILES CCCc1c(OCCCCOc2ccc(OC(C)C(O)=O)cc2)ccc2c(noc12)-c1ccccc1
Show InChI InChI=1S/C29H31NO6/c1-3-9-24-26(17-16-25-27(30-36-28(24)25)21-10-5-4-6-11-21)34-19-8-7-18-33-22-12-14-23(15-13-22)35-20(2)29(31)32/h4-6,10-17,20H,3,7-9,18-19H2,1-2H3,(H,31,32)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
136n/an/an/an/an/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
In vitro binding affinity towards human peroxisome proliferator activated receptor delta (PPAR delta)


Bioorg Med Chem Lett 13: 931-5 (2003)


Article DOI: 10.1016/s0960-894x(02)01029-6
BindingDB Entry DOI: 10.7270/Q2HX1C1Z
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor


(Homo sapiens (human))
BDBM28681
PNG
(5-[(4-{2-[methyl(pyridin-2-yl)amino]ethoxy}phenyl)...)
Show SMILES CN(CCOc1ccc(Cc2sc(=O)[nH]c2O)cc1)c1ccccn1
Show InChI InChI=1S/C18H19N3O3S/c1-21(16-4-2-3-9-19-16)10-11-24-14-7-5-13(6-8-14)12-15-17(22)20-18(23)25-15/h2-9,22H,10-12H2,1H3,(H,20,23)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
136n/an/an/an/an/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
In vitro binding affinity towards human peroxisome proliferator activated receptor gamma (PPAR gamma)


Bioorg Med Chem Lett 13: 931-5 (2003)


Article DOI: 10.1016/s0960-894x(02)01029-6
BindingDB Entry DOI: 10.7270/Q2HX1C1Z
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor


(Homo sapiens (human))
BDBM50124376
PNG
(4-{4-[3-(3-Phenyl-7-propyl-benzo[d]isoxazol-6-ylox...)
Show SMILES CCCc1c(OCCCOc2ccc(CCCC(O)=O)cc2)ccc2c(noc12)-c1ccccc1
Show InChI InChI=1S/C29H31NO5/c1-2-8-24-26(18-17-25-28(30-35-29(24)25)22-10-4-3-5-11-22)34-20-7-19-33-23-15-13-21(14-16-23)9-6-12-27(31)32/h3-5,10-11,13-18H,2,6-9,12,19-20H2,1H3,(H,31,32)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
145n/an/an/an/an/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
In vitro binding affinity towards human peroxisome proliferator activated receptor gamma (PPAR gamma)


Bioorg Med Chem Lett 13: 931-5 (2003)


Article DOI: 10.1016/s0960-894x(02)01029-6
BindingDB Entry DOI: 10.7270/Q2HX1C1Z
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor


(Homo sapiens (human))
BDBM50124371
PNG
((E)-3-{4-[3-(3-Phenyl-7-propyl-benzo[d]isoxazol-6-...)
Show SMILES CCCc1c(OCCCOc2ccc(\C=C\C(O)=O)cc2)ccc2c(noc12)-c1ccccc1
Show InChI InChI=1S/C28H27NO5/c1-2-7-23-25(16-15-24-27(29-34-28(23)24)21-8-4-3-5-9-21)33-19-6-18-32-22-13-10-20(11-14-22)12-17-26(30)31/h3-5,8-17H,2,6-7,18-19H2,1H3,(H,30,31)/b17-12+
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
152n/an/an/an/an/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
In vitro binding affinity towards human peroxisome proliferator activated receptor gamma (PPAR gamma)


Bioorg Med Chem Lett 13: 931-5 (2003)


Article DOI: 10.1016/s0960-894x(02)01029-6
BindingDB Entry DOI: 10.7270/Q2HX1C1Z
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor delta (PPAR delta)


(Homo sapiens (Human))
BDBM50124393
PNG
(4-{4-[2-(3-Phenyl-7-propyl-benzo[d]isoxazol-6-ylox...)
Show SMILES CCCc1c(OCCOc2ccc(CCCC(O)=O)cc2)ccc2c(noc12)-c1ccccc1
Show InChI InChI=1S/C28H29NO5/c1-2-7-23-25(17-16-24-27(29-34-28(23)24)21-9-4-3-5-10-21)33-19-18-32-22-14-12-20(13-15-22)8-6-11-26(30)31/h3-5,9-10,12-17H,2,6-8,11,18-19H2,1H3,(H,30,31)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
156n/an/an/an/an/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
In vitro binding affinity towards human peroxisome proliferator activated receptor delta (PPAR delta)


Bioorg Med Chem Lett 13: 931-5 (2003)


Article DOI: 10.1016/s0960-894x(02)01029-6
BindingDB Entry DOI: 10.7270/Q2HX1C1Z
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor delta (PPAR delta)


(Homo sapiens (Human))
BDBM50124387
PNG
(2-Methyl-2-{3-[4-(3-phenyl-7-propyl-benzo[d]isoxaz...)
Show SMILES CCCc1c(OCCCCOc2cccc(c2)C(C)(C)C(O)=O)ccc2c(noc12)-c1ccccc1
Show InChI InChI=1S/C30H33NO5/c1-4-11-24-26(17-16-25-27(31-36-28(24)25)21-12-6-5-7-13-21)35-19-9-8-18-34-23-15-10-14-22(20-23)30(2,3)29(32)33/h5-7,10,12-17,20H,4,8-9,11,18-19H2,1-3H3,(H,32,33)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
165n/an/an/an/an/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
In vitro binding affinity towards human peroxisome proliferator activated receptor delta (PPAR delta)


Bioorg Med Chem Lett 13: 931-5 (2003)


Article DOI: 10.1016/s0960-894x(02)01029-6
BindingDB Entry DOI: 10.7270/Q2HX1C1Z
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor delta (PPAR delta)


(Homo sapiens (Human))
BDBM50124375
PNG
(2-Methyl-2-{4-[4-(3-phenyl-7-propyl-benzo[d]isoxaz...)
Show SMILES CCCc1c(OCCCCOc2ccc(cc2)C(C)(C)C(O)=O)ccc2c(noc12)-c1ccccc1
Show InChI InChI=1S/C30H33NO5/c1-4-10-24-26(18-17-25-27(31-36-28(24)25)21-11-6-5-7-12-21)35-20-9-8-19-34-23-15-13-22(14-16-23)30(2,3)29(32)33/h5-7,11-18H,4,8-10,19-20H2,1-3H3,(H,32,33)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
203n/an/an/an/an/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
In vitro binding affinity towards human peroxisome proliferator activated receptor delta (PPAR delta)


Bioorg Med Chem Lett 13: 931-5 (2003)


Article DOI: 10.1016/s0960-894x(02)01029-6
BindingDB Entry DOI: 10.7270/Q2HX1C1Z
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha (PPAR alpha)


(Homo sapiens (Human))
BDBM50124382
PNG
(3-Methyl-3-{4-[4-(3-phenyl-7-propyl-benzo[d]isoxaz...)
Show SMILES CCCc1c(OCCCCOc2ccc(cc2)C(C)(C)CC(O)=O)ccc2c(noc12)-c1ccccc1
Show InChI InChI=1S/C31H35NO5/c1-4-10-25-27(18-17-26-29(32-37-30(25)26)22-11-6-5-7-12-22)36-20-9-8-19-35-24-15-13-23(14-16-24)31(2,3)21-28(33)34/h5-7,11-18H,4,8-10,19-21H2,1-3H3,(H,33,34)
UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
213n/an/an/an/an/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
In vitro binding affinity towards human peroxisome proliferator activated receptor alpha (PPAR alpha)


Bioorg Med Chem Lett 13: 931-5 (2003)


Article DOI: 10.1016/s0960-894x(02)01029-6
BindingDB Entry DOI: 10.7270/Q2HX1C1Z
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor


(Homo sapiens (Human))
BDBM50124380
PNG
(2-Methyl-2-{3-[4-(3-phenyl-7-propyl-benzo[d]isoxaz...)
Show SMILES CCCc1c(OCCCCOc2cccc(OC(C)(C)C(O)=O)c2)ccc2c(noc12)-c1ccccc1
Show InChI InChI=1S/C30H33NO6/c1-4-11-24-26(17-16-25-27(31-37-28(24)25)21-12-6-5-7-13-21)35-19-9-8-18-34-22-14-10-15-23(20-22)36-30(2,3)29(32)33/h5-7,10,12-17,20H,4,8-9,11,18-19H2,1-3H3,(H,32,33)
UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
255n/an/an/an/an/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
In vitro binding affinity towards human peroxisome proliferator activated receptor alpha (PPAR alpha)


Bioorg Med Chem Lett 13: 931-5 (2003)


Article DOI: 10.1016/s0960-894x(02)01029-6
BindingDB Entry DOI: 10.7270/Q2HX1C1Z
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor delta (PPAR delta)


(Homo sapiens (Human))
BDBM50124372
PNG
((E)-3-{4-[4-(3-Phenyl-7-propyl-benzo[d]isoxazol-6-...)
Show SMILES CCCc1c(OCCCCOc2ccc(\C=C\C(O)=O)cc2)ccc2c(noc12)-c1ccccc1
Show InChI InChI=1S/C29H29NO5/c1-2-8-24-26(17-16-25-28(30-35-29(24)25)22-9-4-3-5-10-22)34-20-7-6-19-33-23-14-11-21(12-15-23)13-18-27(31)32/h3-5,9-18H,2,6-8,19-20H2,1H3,(H,31,32)/b18-13+
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
265n/an/an/an/an/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
In vitro binding affinity towards human peroxisome proliferator activated receptor delta (PPAR delta)


Bioorg Med Chem Lett 13: 931-5 (2003)


Article DOI: 10.1016/s0960-894x(02)01029-6
BindingDB Entry DOI: 10.7270/Q2HX1C1Z
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor


(Homo sapiens (human))
BDBM50124383
PNG
(3-{4-[2-(3-Phenyl-7-propyl-benzo[d]isoxazol-6-ylox...)
Show SMILES CCCc1c(OCCOc2ccc(CCC(O)=O)cc2)ccc2c(noc12)-c1ccccc1
Show InChI InChI=1S/C27H27NO5/c1-2-6-22-24(15-14-23-26(28-33-27(22)23)20-7-4-3-5-8-20)32-18-17-31-21-12-9-19(10-13-21)11-16-25(29)30/h3-5,7-10,12-15H,2,6,11,16-18H2,1H3,(H,29,30)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
304n/an/an/an/an/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
In vitro binding affinity towards human peroxisome proliferator activated receptor gamma (PPAR gamma)


Bioorg Med Chem Lett 13: 931-5 (2003)


Article DOI: 10.1016/s0960-894x(02)01029-6
BindingDB Entry DOI: 10.7270/Q2HX1C1Z
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha (PPAR alpha)


(Homo sapiens (Human))
BDBM50124393
PNG
(4-{4-[2-(3-Phenyl-7-propyl-benzo[d]isoxazol-6-ylox...)
Show SMILES CCCc1c(OCCOc2ccc(CCCC(O)=O)cc2)ccc2c(noc12)-c1ccccc1
Show InChI InChI=1S/C28H29NO5/c1-2-7-23-25(17-16-24-27(29-34-28(23)24)21-9-4-3-5-10-21)33-19-18-32-22-14-12-20(13-15-22)8-6-11-26(30)31/h3-5,9-10,12-17H,2,6-8,11,18-19H2,1H3,(H,30,31)
UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
305n/an/an/an/an/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
In vitro binding affinity towards human peroxisome proliferator activated receptor alpha (PPAR alpha)


Bioorg Med Chem Lett 13: 931-5 (2003)


Article DOI: 10.1016/s0960-894x(02)01029-6
BindingDB Entry DOI: 10.7270/Q2HX1C1Z
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor delta (PPAR delta)


(Homo sapiens (Human))
BDBM50124389
PNG
(2,2-Dimethyl-3-{4-[4-(3-phenyl-7-propyl-benzo[d]is...)
Show SMILES CCCc1c(OCCCCOc2ccc(CC(C)(C)C(O)=O)cc2)ccc2c(noc12)-c1ccccc1
Show InChI InChI=1S/C31H35NO5/c1-4-10-25-27(18-17-26-28(32-37-29(25)26)23-11-6-5-7-12-23)36-20-9-8-19-35-24-15-13-22(14-16-24)21-31(2,3)30(33)34/h5-7,11-18H,4,8-10,19-21H2,1-3H3,(H,33,34)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
317n/an/an/an/an/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
In vitro binding affinity towards human peroxisome proliferator activated receptor delta (PPAR delta)


Bioorg Med Chem Lett 13: 931-5 (2003)


Article DOI: 10.1016/s0960-894x(02)01029-6
BindingDB Entry DOI: 10.7270/Q2HX1C1Z
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha (PPAR alpha)


(Homo sapiens (Human))
BDBM50124368
PNG
(3-{3-[4-(3-Phenyl-7-propyl-benzo[d]isoxazol-6-ylox...)
Show SMILES CCCc1c(OCCCCOc2cccc(CCC(O)=O)c2)ccc2c(noc12)-c1ccccc1
Show InChI InChI=1S/C29H31NO5/c1-2-9-24-26(16-15-25-28(30-35-29(24)25)22-11-4-3-5-12-22)34-19-7-6-18-33-23-13-8-10-21(20-23)14-17-27(31)32/h3-5,8,10-13,15-16,20H,2,6-7,9,14,17-19H2,1H3,(H,31,32)
UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
329n/an/an/an/an/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
In vitro binding affinity towards human peroxisome proliferator activated receptor alpha (PPAR alpha)


Bioorg Med Chem Lett 13: 931-5 (2003)


Article DOI: 10.1016/s0960-894x(02)01029-6
BindingDB Entry DOI: 10.7270/Q2HX1C1Z
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor


(Homo sapiens (human))
BDBM50124391
PNG
(CHEMBL176421 | {2-[4-(3-Phenyl-7-propyl-benzo[d]is...)
Show SMILES CCCc1c(OCCCCOc2ccccc2CC(O)=O)ccc2c(noc12)-c1ccccc1
Show InChI InChI=1S/C28H29NO5/c1-2-10-22-25(16-15-23-27(29-34-28(22)23)20-11-4-3-5-12-20)33-18-9-8-17-32-24-14-7-6-13-21(24)19-26(30)31/h3-7,11-16H,2,8-10,17-19H2,1H3,(H,30,31)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
348n/an/an/an/an/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
In vitro binding affinity towards human peroxisome proliferator activated receptor gamma (PPAR gamma)


Bioorg Med Chem Lett 13: 931-5 (2003)


Article DOI: 10.1016/s0960-894x(02)01029-6
BindingDB Entry DOI: 10.7270/Q2HX1C1Z
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor


(Homo sapiens (human))
BDBM50124388
PNG
(3-{3-[3-(3-Phenyl-7-propyl-benzo[d]isoxazol-6-ylox...)
Show SMILES CCCc1c(OCCCOc2cccc(CCC(O)=O)c2)ccc2c(noc12)-c1ccccc1
Show InChI InChI=1S/C28H29NO5/c1-2-8-23-25(15-14-24-27(29-34-28(23)24)21-10-4-3-5-11-21)33-18-7-17-32-22-12-6-9-20(19-22)13-16-26(30)31/h3-6,9-12,14-15,19H,2,7-8,13,16-18H2,1H3,(H,30,31)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
448n/an/an/an/an/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
In vitro binding affinity towards human peroxisome proliferator activated receptor gamma (PPAR gamma)


Bioorg Med Chem Lett 13: 931-5 (2003)


Article DOI: 10.1016/s0960-894x(02)01029-6
BindingDB Entry DOI: 10.7270/Q2HX1C1Z
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha (PPAR alpha)


(Homo sapiens (Human))
BDBM50124390
PNG
(CHEMBL175213 | {2-[3-(3-Phenyl-7-propyl-benzo[d]is...)
Show SMILES CCCc1c(OCCCOc2ccccc2CC(O)=O)ccc2c(noc12)-c1ccccc1
Show InChI InChI=1S/C27H27NO5/c1-2-9-21-24(15-14-22-26(28-33-27(21)22)19-10-4-3-5-11-19)32-17-8-16-31-23-13-7-6-12-20(23)18-25(29)30/h3-7,10-15H,2,8-9,16-18H2,1H3,(H,29,30)
UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
489n/an/an/an/an/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
In vitro binding affinity towards human peroxisome proliferator activated receptor alpha (PPAR alpha)


Bioorg Med Chem Lett 13: 931-5 (2003)


Article DOI: 10.1016/s0960-894x(02)01029-6
BindingDB Entry DOI: 10.7270/Q2HX1C1Z
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor


(Homo sapiens (human))
BDBM50124390
PNG
(CHEMBL175213 | {2-[3-(3-Phenyl-7-propyl-benzo[d]is...)
Show SMILES CCCc1c(OCCCOc2ccccc2CC(O)=O)ccc2c(noc12)-c1ccccc1
Show InChI InChI=1S/C27H27NO5/c1-2-9-21-24(15-14-22-26(28-33-27(21)22)19-10-4-3-5-11-19)32-17-8-16-31-23-13-7-6-12-20(23)18-25(29)30/h3-7,10-15H,2,8-9,16-18H2,1H3,(H,29,30)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
498n/an/an/an/an/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
In vitro binding affinity towards human peroxisome proliferator activated receptor gamma (PPAR gamma)


Bioorg Med Chem Lett 13: 931-5 (2003)


Article DOI: 10.1016/s0960-894x(02)01029-6
BindingDB Entry DOI: 10.7270/Q2HX1C1Z
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor delta (PPAR delta)


(Homo sapiens (Human))
BDBM50124385
PNG
(3-[4-(3-Phenyl-7-propyl-benzo[d]isoxazol-6-yloxy)-...)
Show SMILES CCCc1c(OCCCCOc2cccc(c2)C(O)=O)ccc2c(noc12)-c1ccccc1
Show InChI InChI=1S/C27H27NO5/c1-2-9-22-24(15-14-23-25(28-33-26(22)23)19-10-4-3-5-11-19)32-17-7-6-16-31-21-13-8-12-20(18-21)27(29)30/h3-5,8,10-15,18H,2,6-7,9,16-17H2,1H3,(H,29,30)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
508n/an/an/an/an/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
In vitro binding affinity towards human peroxisome proliferator activated receptor delta (PPAR delta)


Bioorg Med Chem Lett 13: 931-5 (2003)


Article DOI: 10.1016/s0960-894x(02)01029-6
BindingDB Entry DOI: 10.7270/Q2HX1C1Z
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor delta (PPAR delta)


(Homo sapiens (Human))
BDBM50124382
PNG
(3-Methyl-3-{4-[4-(3-phenyl-7-propyl-benzo[d]isoxaz...)
Show SMILES CCCc1c(OCCCCOc2ccc(cc2)C(C)(C)CC(O)=O)ccc2c(noc12)-c1ccccc1
Show InChI InChI=1S/C31H35NO5/c1-4-10-25-27(18-17-26-29(32-37-30(25)26)22-11-6-5-7-12-22)36-20-9-8-19-35-24-15-13-23(14-16-24)31(2,3)21-28(33)34/h5-7,11-18H,4,8-10,19-21H2,1-3H3,(H,33,34)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
529n/an/an/an/an/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
In vitro binding affinity towards human peroxisome proliferator activated receptor delta (PPAR delta)


Bioorg Med Chem Lett 13: 931-5 (2003)


Article DOI: 10.1016/s0960-894x(02)01029-6
BindingDB Entry DOI: 10.7270/Q2HX1C1Z
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor


(Homo sapiens (human))
BDBM50124393
PNG
(4-{4-[2-(3-Phenyl-7-propyl-benzo[d]isoxazol-6-ylox...)
Show SMILES CCCc1c(OCCOc2ccc(CCCC(O)=O)cc2)ccc2c(noc12)-c1ccccc1
Show InChI InChI=1S/C28H29NO5/c1-2-7-23-25(17-16-24-27(29-34-28(23)24)21-9-4-3-5-10-21)33-19-18-32-22-14-12-20(13-15-22)8-6-11-26(30)31/h3-5,9-10,12-17H,2,6-8,11,18-19H2,1H3,(H,30,31)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
616n/an/an/an/an/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
In vitro binding affinity towards human peroxisome proliferator activated receptor gamma (PPAR gamma)


Bioorg Med Chem Lett 13: 931-5 (2003)


Article DOI: 10.1016/s0960-894x(02)01029-6
BindingDB Entry DOI: 10.7270/Q2HX1C1Z
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor


(Homo sapiens (human))
BDBM50124381
PNG
(CHEMBL172718 | {3-[3-(3-Phenyl-7-propyl-benzo[d]is...)
Show SMILES CCCc1c(OCCCOc2cccc(CC(O)=O)c2)ccc2c(noc12)-c1ccccc1
Show InChI InChI=1S/C27H27NO5/c1-2-8-22-24(14-13-23-26(28-33-27(22)23)20-10-4-3-5-11-20)32-16-7-15-31-21-12-6-9-19(17-21)18-25(29)30/h3-6,9-14,17H,2,7-8,15-16,18H2,1H3,(H,29,30)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
662n/an/an/an/an/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
In vitro binding affinity towards human peroxisome proliferator activated receptor gamma (PPAR gamma)


Bioorg Med Chem Lett 13: 931-5 (2003)


Article DOI: 10.1016/s0960-894x(02)01029-6
BindingDB Entry DOI: 10.7270/Q2HX1C1Z
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha (PPAR alpha)


(Homo sapiens (Human))
BDBM50124395
PNG
(4-[4-(3-Phenyl-7-propyl-benzo[d]isoxazol-6-yloxy)-...)
Show SMILES CCCc1c(OCCCCOc2ccc(cc2)C(O)=O)ccc2c(noc12)-c1ccccc1
Show InChI InChI=1S/C27H27NO5/c1-2-8-22-24(16-15-23-25(28-33-26(22)23)19-9-4-3-5-10-19)32-18-7-6-17-31-21-13-11-20(12-14-21)27(29)30/h3-5,9-16H,2,6-8,17-18H2,1H3,(H,29,30)
UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
920n/an/an/an/an/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
In vitro binding affinity towards human peroxisome proliferator activated receptor alpha (PPAR alpha)


Bioorg Med Chem Lett 13: 931-5 (2003)


Article DOI: 10.1016/s0960-894x(02)01029-6
BindingDB Entry DOI: 10.7270/Q2HX1C1Z
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor


(Homo sapiens (human))
BDBM50124373
PNG
(3-{2-[3-(3-Phenyl-7-propyl-benzo[d]isoxazol-6-ylox...)
Show SMILES CCCc1c(OCCCOc2ccccc2CCC(O)=O)ccc2c(noc12)-c1ccccc1
Show InChI InChI=1S/C28H29NO5/c1-2-9-22-25(16-15-23-27(29-34-28(22)23)21-11-4-3-5-12-21)33-19-8-18-32-24-13-7-6-10-20(24)14-17-26(30)31/h3-7,10-13,15-16H,2,8-9,14,17-19H2,1H3,(H,30,31)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
1.33E+3n/an/an/an/an/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
In vitro binding affinity towards human peroxisome proliferator activated receptor gamma (PPAR gamma)


Bioorg Med Chem Lett 13: 931-5 (2003)


Article DOI: 10.1016/s0960-894x(02)01029-6
BindingDB Entry DOI: 10.7270/Q2HX1C1Z
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor delta (PPAR delta)


(Homo sapiens (Human))
BDBM50124373
PNG
(3-{2-[3-(3-Phenyl-7-propyl-benzo[d]isoxazol-6-ylox...)
Show SMILES CCCc1c(OCCCOc2ccccc2CCC(O)=O)ccc2c(noc12)-c1ccccc1
Show InChI InChI=1S/C28H29NO5/c1-2-9-22-25(16-15-23-27(29-34-28(22)23)21-11-4-3-5-12-21)33-19-8-18-32-24-13-7-6-10-20(24)14-17-26(30)31/h3-7,10-13,15-16H,2,8-9,14,17-19H2,1H3,(H,30,31)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
3.52E+3n/an/an/an/an/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
In vitro binding affinity towards human peroxisome proliferator activated receptor delta (PPAR delta)


Bioorg Med Chem Lett 13: 931-5 (2003)


Article DOI: 10.1016/s0960-894x(02)01029-6
BindingDB Entry DOI: 10.7270/Q2HX1C1Z
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor


(Homo sapiens (human))
BDBM50124395
PNG
(4-[4-(3-Phenyl-7-propyl-benzo[d]isoxazol-6-yloxy)-...)
Show SMILES CCCc1c(OCCCCOc2ccc(cc2)C(O)=O)ccc2c(noc12)-c1ccccc1
Show InChI InChI=1S/C27H27NO5/c1-2-8-22-24(16-15-23-25(28-33-26(22)23)19-9-4-3-5-10-19)32-18-7-6-17-31-21-13-11-20(12-14-21)27(29)30/h3-5,9-16H,2,6-8,17-18H2,1H3,(H,29,30)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
>5.30E+3n/an/an/an/an/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
In vitro binding affinity towards human peroxisome proliferator activated receptor gamma (PPAR gamma)


Bioorg Med Chem Lett 13: 931-5 (2003)


Article DOI: 10.1016/s0960-894x(02)01029-6
BindingDB Entry DOI: 10.7270/Q2HX1C1Z
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor delta (PPAR delta)


(Homo sapiens (Human))
BDBM50124395
PNG
(4-[4-(3-Phenyl-7-propyl-benzo[d]isoxazol-6-yloxy)-...)
Show SMILES CCCc1c(OCCCCOc2ccc(cc2)C(O)=O)ccc2c(noc12)-c1ccccc1
Show InChI InChI=1S/C27H27NO5/c1-2-8-22-24(16-15-23-25(28-33-26(22)23)19-9-4-3-5-10-19)32-18-7-6-17-31-21-13-11-20(12-14-21)27(29)30/h3-5,9-16H,2,6-8,17-18H2,1H3,(H,29,30)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
>1.40E+4n/an/an/an/an/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
In vitro binding affinity towards human peroxisome proliferator activated receptor delta (PPAR delta)


Bioorg Med Chem Lett 13: 931-5 (2003)


Article DOI: 10.1016/s0960-894x(02)01029-6
BindingDB Entry DOI: 10.7270/Q2HX1C1Z
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor delta (PPAR delta)


(Homo sapiens (Human))
BDBM28681
PNG
(5-[(4-{2-[methyl(pyridin-2-yl)amino]ethoxy}phenyl)...)
Show SMILES CN(CCOc1ccc(Cc2sc(=O)[nH]c2O)cc1)c1ccccn1
Show InChI InChI=1S/C18H19N3O3S/c1-21(16-4-2-3-9-19-16)10-11-24-14-7-5-13(6-8-14)12-15-17(22)20-18(23)25-15/h2-9,22H,10-12H2,1H3,(H,20,23)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
>3.33E+4n/an/an/an/an/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
In vitro binding affinity towards human peroxisome proliferator activated receptor delta (PPAR delta)


Bioorg Med Chem Lett 13: 931-5 (2003)


Article DOI: 10.1016/s0960-894x(02)01029-6
BindingDB Entry DOI: 10.7270/Q2HX1C1Z
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha (PPAR alpha)


(Homo sapiens (Human))
BDBM28681
PNG
(5-[(4-{2-[methyl(pyridin-2-yl)amino]ethoxy}phenyl)...)
Show SMILES CN(CCOc1ccc(Cc2sc(=O)[nH]c2O)cc1)c1ccccn1
Show InChI InChI=1S/C18H19N3O3S/c1-21(16-4-2-3-9-19-16)10-11-24-14-7-5-13(6-8-14)12-15-17(22)20-18(23)25-15/h2-9,22H,10-12H2,1H3,(H,20,23)
UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
>3.33E+4n/an/an/an/an/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
In vitro binding affinity towards human peroxisome proliferator activated receptor alpha (PPAR alpha)


Bioorg Med Chem Lett 13: 931-5 (2003)


Article DOI: 10.1016/s0960-894x(02)01029-6
BindingDB Entry DOI: 10.7270/Q2HX1C1Z
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha (PPAR alpha)


(Homo sapiens (Human))
BDBM50124373
PNG
(3-{2-[3-(3-Phenyl-7-propyl-benzo[d]isoxazol-6-ylox...)
Show SMILES CCCc1c(OCCCOc2ccccc2CCC(O)=O)ccc2c(noc12)-c1ccccc1
Show InChI InChI=1S/C28H29NO5/c1-2-9-22-25(16-15-23-27(29-34-28(22)23)21-11-4-3-5-12-21)33-19-8-18-32-24-13-7-6-10-20(24)14-17-26(30)31/h3-7,10-13,15-16H,2,8-9,14,17-19H2,1H3,(H,30,31)
UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
>3.33E+4n/an/an/an/an/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
In vitro binding affinity towards human peroxisome proliferator activated receptor alpha (PPAR alpha)


Bioorg Med Chem Lett 13: 931-5 (2003)


Article DOI: 10.1016/s0960-894x(02)01029-6
BindingDB Entry DOI: 10.7270/Q2HX1C1Z
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor


(Homo sapiens (Human))
BDBM50124387
PNG
(2-Methyl-2-{3-[4-(3-phenyl-7-propyl-benzo[d]isoxaz...)
Show SMILES CCCc1c(OCCCCOc2cccc(c2)C(C)(C)C(O)=O)ccc2c(noc12)-c1ccccc1
Show InChI InChI=1S/C30H33NO5/c1-4-11-24-26(17-16-25-27(31-36-28(24)25)21-12-6-5-7-13-21)35-19-9-8-18-34-23-15-10-14-22(20-23)30(2,3)29(32)33/h5-7,10,12-17,20H,4,8-9,11,18-19H2,1-3H3,(H,32,33)
UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/a 50n/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
In vitro binding affinity towards human peroxisome proliferator activated receptor alpha (PPAR alpha)


Bioorg Med Chem Lett 13: 931-5 (2003)


Article DOI: 10.1016/s0960-894x(02)01029-6
BindingDB Entry DOI: 10.7270/Q2HX1C1Z
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor


(Homo sapiens (human))
BDBM50124370
PNG
(CHEMBL173409 | {3-[4-(3-Phenyl-7-propyl-benzo[d]is...)
Show SMILES CCCc1c(OCCCCOc2cccc(OCC(O)=O)c2)ccc2c(noc12)-c1ccccc1
Show InChI InChI=1S/C28H29NO6/c1-2-9-23-25(15-14-24-27(29-35-28(23)24)20-10-4-3-5-11-20)33-17-7-6-16-32-21-12-8-13-22(18-21)34-19-26(30)31/h3-5,8,10-15,18H,2,6-7,9,16-17,19H2,1H3,(H,30,31)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/an/an/a 87n/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
In vitro binding affinity towards human peroxisome proliferator activated receptor alpha (PPAR alpha)


Bioorg Med Chem Lett 13: 931-5 (2003)


Article DOI: 10.1016/s0960-894x(02)01029-6
BindingDB Entry DOI: 10.7270/Q2HX1C1Z
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor


(Homo sapiens (Human))
BDBM50124371
PNG
((E)-3-{4-[3-(3-Phenyl-7-propyl-benzo[d]isoxazol-6-...)
Show SMILES CCCc1c(OCCCOc2ccc(\C=C\C(O)=O)cc2)ccc2c(noc12)-c1ccccc1
Show InChI InChI=1S/C28H27NO5/c1-2-7-23-25(16-15-24-27(29-34-28(23)24)21-8-4-3-5-9-21)33-19-6-18-32-22-13-10-20(11-14-22)12-17-26(30)31/h3-5,8-17H,2,6-7,18-19H2,1H3,(H,30,31)/b17-12+
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/a 148n/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Agonistic activity was determined in COS1 cells transfected with GAL 4-PPAR gamma receptor


Bioorg Med Chem Lett 13: 931-5 (2003)


Article DOI: 10.1016/s0960-894x(02)01029-6
BindingDB Entry DOI: 10.7270/Q2HX1C1Z
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor delta (PPAR delta)


(Homo sapiens (Human))
BDBM50124384
PNG
(CHEMBL173494 | {4-[3-(3-Phenyl-7-propyl-benzo[d]is...)
Show SMILES CCCc1c(OCCCOc2ccc(OCC(O)=O)cc2)ccc2c(noc12)-c1ccccc1
Show InChI InChI=1S/C27H27NO6/c1-2-7-22-24(15-14-23-26(28-34-27(22)23)19-8-4-3-5-9-19)32-17-6-16-31-20-10-12-21(13-11-20)33-18-25(29)30/h3-5,8-15H,2,6-7,16-18H2,1H3,(H,29,30)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/an/an/a 16n/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Agonistic activity was determined in COS1 cells transfected with GAL 4-PPAR delta receptor


Bioorg Med Chem Lett 13: 931-5 (2003)


Article DOI: 10.1016/s0960-894x(02)01029-6
BindingDB Entry DOI: 10.7270/Q2HX1C1Z
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor


(Homo sapiens (human))
BDBM33283
PNG
((3-{4-[(3-phenyl-7-propyl-1,2-benzisoxazol-6-yl)ox...)
Show SMILES CCCc1c(OCCCCOc2cccc(CC(O)=O)c2)ccc2c(noc12)-c1ccccc1
Show InChI InChI=1S/C28H29NO5/c1-2-9-23-25(15-14-24-27(29-34-28(23)24)21-11-4-3-5-12-21)33-17-7-6-16-32-22-13-8-10-20(18-22)19-26(30)31/h3-5,8,10-15,18H,2,6-7,9,16-17,19H2,1H3,(H,30,31)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/an/an/a 6n/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Agonistic activity was determined in COS1 cells transfected with GAL 4-PPAR gamma receptor


Bioorg Med Chem Lett 13: 931-5 (2003)


Article DOI: 10.1016/s0960-894x(02)01029-6
BindingDB Entry DOI: 10.7270/Q2HX1C1Z
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor delta (PPAR delta)


(Homo sapiens (Human))
BDBM50124379
PNG
(2-(4-(3-(3-phenyl-7-propylbenzo[d]isoxazol-6-yloxy...)
Show SMILES CCCc1c(OCCCOc2ccc(CC(O)=O)cc2)ccc2c(noc12)-c1ccccc1
Show InChI InChI=1S/C27H27NO5/c1-2-7-22-24(15-14-23-26(28-33-27(22)23)20-8-4-3-5-9-20)32-17-6-16-31-21-12-10-19(11-13-21)18-25(29)30/h3-5,8-15H,2,6-7,16-18H2,1H3,(H,29,30)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/an/an/a 147n/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Agonistic activity was determined in COS1 cells transfected with GAL 4-PPAR delta receptor


Bioorg Med Chem Lett 13: 931-5 (2003)


Article DOI: 10.1016/s0960-894x(02)01029-6
BindingDB Entry DOI: 10.7270/Q2HX1C1Z
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor


(Homo sapiens (Human))
BDBM50124379
PNG
(2-(4-(3-(3-phenyl-7-propylbenzo[d]isoxazol-6-yloxy...)
Show SMILES CCCc1c(OCCCOc2ccc(CC(O)=O)cc2)ccc2c(noc12)-c1ccccc1
Show InChI InChI=1S/C27H27NO5/c1-2-7-22-24(15-14-23-26(28-33-27(22)23)20-8-4-3-5-9-20)32-17-6-16-31-21-12-10-19(11-13-21)18-25(29)30/h3-5,8-15H,2,6-7,16-18H2,1H3,(H,29,30)
UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/an/an/a 3n/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Agonistic activity was determined in COS1 cells transfected with GAL 4-PPAR gamma receptor


Bioorg Med Chem Lett 13: 931-5 (2003)


Article DOI: 10.1016/s0960-894x(02)01029-6
BindingDB Entry DOI: 10.7270/Q2HX1C1Z
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor


(Homo sapiens (Human))
BDBM50124375
PNG
(2-Methyl-2-{4-[4-(3-phenyl-7-propyl-benzo[d]isoxaz...)
Show SMILES CCCc1c(OCCCCOc2ccc(cc2)C(C)(C)C(O)=O)ccc2c(noc12)-c1ccccc1
Show InChI InChI=1S/C30H33NO5/c1-4-10-24-26(18-17-25-27(31-36-28(24)25)21-11-6-5-7-12-21)35-20-9-8-19-34-23-15-13-22(14-16-23)30(2,3)29(32)33/h5-7,11-18H,4,8-10,19-20H2,1-3H3,(H,32,33)
UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/a 2n/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
In vitro binding affinity towards human peroxisome proliferator activated receptor gamma (PPAR gamma)


Bioorg Med Chem Lett 13: 931-5 (2003)


Article DOI: 10.1016/s0960-894x(02)01029-6
BindingDB Entry DOI: 10.7270/Q2HX1C1Z
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor delta (PPAR delta)


(Homo sapiens (Human))
BDBM33283
PNG
((3-{4-[(3-phenyl-7-propyl-1,2-benzisoxazol-6-yl)ox...)
Show SMILES CCCc1c(OCCCCOc2cccc(CC(O)=O)c2)ccc2c(noc12)-c1ccccc1
Show InChI InChI=1S/C28H29NO5/c1-2-9-23-25(15-14-24-27(29-34-28(23)24)21-11-4-3-5-12-21)33-17-7-6-16-32-22-13-8-10-20(18-22)19-26(30)31/h3-5,8,10-15,18H,2,6-7,9,16-17,19H2,1H3,(H,30,31)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/an/an/a 20n/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Agonistic activity was determined in COS1 cells transfected with GAL 4-PPAR delta receptor


Bioorg Med Chem Lett 13: 931-5 (2003)


Article DOI: 10.1016/s0960-894x(02)01029-6
BindingDB Entry DOI: 10.7270/Q2HX1C1Z
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor


(Homo sapiens (human))
BDBM50124372
PNG
((E)-3-{4-[4-(3-Phenyl-7-propyl-benzo[d]isoxazol-6-...)
Show SMILES CCCc1c(OCCCCOc2ccc(\C=C\C(O)=O)cc2)ccc2c(noc12)-c1ccccc1
Show InChI InChI=1S/C29H29NO5/c1-2-8-24-26(17-16-25-28(30-35-29(24)25)22-9-4-3-5-10-22)34-20-7-6-19-33-23-14-11-21(12-15-23)13-18-27(31)32/h3-5,9-18H,2,6-8,19-20H2,1H3,(H,31,32)/b18-13+
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/a 29n/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Agonistic activity was determined in COS1 cells transfected with GAL 4-PPAR gamma receptor


Bioorg Med Chem Lett 13: 931-5 (2003)


Article DOI: 10.1016/s0960-894x(02)01029-6
BindingDB Entry DOI: 10.7270/Q2HX1C1Z
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor


(Homo sapiens (Human))
BDBM50124387
PNG
(2-Methyl-2-{3-[4-(3-phenyl-7-propyl-benzo[d]isoxaz...)
Show SMILES CCCc1c(OCCCCOc2cccc(c2)C(C)(C)C(O)=O)ccc2c(noc12)-c1ccccc1
Show InChI InChI=1S/C30H33NO5/c1-4-11-24-26(17-16-25-27(31-36-28(24)25)21-12-6-5-7-13-21)35-19-9-8-18-34-23-15-10-14-22(20-23)30(2,3)29(32)33/h5-7,10,12-17,20H,4,8-9,11,18-19H2,1-3H3,(H,32,33)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/a 400n/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Agonistic activity was determined in COS1 cells transfected with GAL 4-PPAR delta receptor


Bioorg Med Chem Lett 13: 931-5 (2003)


Article DOI: 10.1016/s0960-894x(02)01029-6
BindingDB Entry DOI: 10.7270/Q2HX1C1Z
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor delta (PPAR delta)


(Homo sapiens (Human))
BDBM50124378
PNG
(2-{4-[3-(3-Phenyl-7-propyl-benzo[d]isoxazol-6-ylox...)
Show SMILES CCCc1c(OCCCOc2ccc(OC(C)C(O)=O)cc2)ccc2c(noc12)-c1ccccc1
Show InChI InChI=1S/C28H29NO6/c1-3-8-23-25(16-15-24-26(29-35-27(23)24)20-9-5-4-6-10-20)33-18-7-17-32-21-11-13-22(14-12-21)34-19(2)28(30)31/h4-6,9-16,19H,3,7-8,17-18H2,1-2H3,(H,30,31)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/an/an/a 13n/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Agonistic activity was determined in COS1 cells transfected with GAL 4-PPAR delta receptor


Bioorg Med Chem Lett 13: 931-5 (2003)


Article DOI: 10.1016/s0960-894x(02)01029-6
BindingDB Entry DOI: 10.7270/Q2HX1C1Z
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor


(Homo sapiens (human))
BDBM50124386
PNG
(CHEMBL367311 | {4-[4-(3-Phenyl-7-propyl-benzo[d]is...)
Show SMILES CCCc1c(OCCCCOc2ccc(CC(O)=O)cc2)ccc2c(noc12)-c1ccccc1
Show InChI InChI=1S/C28H29NO5/c1-2-8-23-25(16-15-24-27(29-34-28(23)24)21-9-4-3-5-10-21)33-18-7-6-17-32-22-13-11-20(12-14-22)19-26(30)31/h3-5,9-16H,2,6-8,17-19H2,1H3,(H,30,31)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/a 60n/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Agonistic activity was determined in COS1 cells transfected with GAL 4-PPAR gamma receptor


Bioorg Med Chem Lett 13: 931-5 (2003)


Article DOI: 10.1016/s0960-894x(02)01029-6
BindingDB Entry DOI: 10.7270/Q2HX1C1Z
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor


(Homo sapiens (human))
BDBM50124374
PNG
(3-{4-[4-(3-Phenyl-7-propyl-benzo[d]isoxazol-6-ylox...)
Show SMILES CCCc1c(OCCCCOc2ccc(CCC(O)=O)cc2)ccc2c(noc12)-c1ccccc1
Show InChI InChI=1S/C29H31NO5/c1-2-8-24-26(17-16-25-28(30-35-29(24)25)22-9-4-3-5-10-22)34-20-7-6-19-33-23-14-11-21(12-15-23)13-18-27(31)32/h3-5,9-12,14-17H,2,6-8,13,18-20H2,1H3,(H,31,32)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/an/an/a 485n/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
In vitro binding affinity towards human peroxisome proliferator activated receptor delta (PPAR delta)


Bioorg Med Chem Lett 13: 931-5 (2003)


Article DOI: 10.1016/s0960-894x(02)01029-6
BindingDB Entry DOI: 10.7270/Q2HX1C1Z
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha (PPAR alpha)


(Homo sapiens (Human))
BDBM50124385
PNG
(3-[4-(3-Phenyl-7-propyl-benzo[d]isoxazol-6-yloxy)-...)
Show SMILES CCCc1c(OCCCCOc2cccc(c2)C(O)=O)ccc2c(noc12)-c1ccccc1
Show InChI InChI=1S/C27H27NO5/c1-2-9-22-24(15-14-23-25(28-33-26(22)23)19-10-4-3-5-11-19)32-17-7-6-16-31-21-13-8-12-20(18-21)27(29)30/h3-5,8,10-15,18H,2,6-7,9,16-17H2,1H3,(H,29,30)
UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/a 8n/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Agonistic activity was determined in COS1 cells transfected with GAL 4-PPAR alpha receptor


Bioorg Med Chem Lett 13: 931-5 (2003)


Article DOI: 10.1016/s0960-894x(02)01029-6
BindingDB Entry DOI: 10.7270/Q2HX1C1Z
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha (PPAR alpha)


(Homo sapiens (Human))
BDBM50124394
PNG
(2-Methyl-2-{4-[4-(3-phenyl-7-propyl-benzo[d]isoxaz...)
Show SMILES CCCc1c(OCCCCOc2ccc(OC(C)(C)C(O)=O)cc2)ccc2c(noc12)-c1ccccc1
Show InChI InChI=1S/C30H33NO6/c1-4-10-24-26(18-17-25-27(31-37-28(24)25)21-11-6-5-7-12-21)35-20-9-8-19-34-22-13-15-23(16-14-22)36-30(2,3)29(32)33/h5-7,11-18H,4,8-10,19-20H2,1-3H3,(H,32,33)
UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/a 2n/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Agonistic activity was determined in COS1 cells transfected with GAL 4-PPAR alpha receptor


Bioorg Med Chem Lett 13: 931-5 (2003)


Article DOI: 10.1016/s0960-894x(02)01029-6
BindingDB Entry DOI: 10.7270/Q2HX1C1Z
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha (PPAR alpha)


(Homo sapiens (Human))
BDBM50124372
PNG
((E)-3-{4-[4-(3-Phenyl-7-propyl-benzo[d]isoxazol-6-...)
Show SMILES CCCc1c(OCCCCOc2ccc(\C=C\C(O)=O)cc2)ccc2c(noc12)-c1ccccc1
Show InChI InChI=1S/C29H29NO5/c1-2-8-24-26(17-16-25-28(30-35-29(24)25)22-9-4-3-5-10-22)34-20-7-6-19-33-23-14-11-21(12-15-23)13-18-27(31)32/h3-5,9-18H,2,6-8,19-20H2,1H3,(H,31,32)/b18-13+
UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/a 13n/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Agonistic activity was determined in COS1 cells transfected with GAL 4-PPAR alpha receptor


Bioorg Med Chem Lett 13: 931-5 (2003)


Article DOI: 10.1016/s0960-894x(02)01029-6
BindingDB Entry DOI: 10.7270/Q2HX1C1Z
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor


(Homo sapiens (Human))
BDBM50124369
PNG
(CHEMBL367019 | {3-Chloro-4-[3-(3-phenyl-7-propyl-b...)
Show SMILES CCCc1c(OCCCSc2ccc(CC(O)=O)cc2Cl)ccc2c(noc12)-c1ccccc1
Show InChI InChI=1S/C27H26ClNO4S/c1-2-7-20-23(12-11-21-26(29-33-27(20)21)19-8-4-3-5-9-19)32-14-6-15-34-24-13-10-18(16-22(24)28)17-25(30)31/h3-5,8-13,16H,2,6-7,14-15,17H2,1H3,(H,30,31)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/an/an/a 3n/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
In vitro binding affinity towards human peroxisome proliferator activated receptor gamma (PPAR gamma)


Bioorg Med Chem Lett 13: 931-5 (2003)


Article DOI: 10.1016/s0960-894x(02)01029-6
BindingDB Entry DOI: 10.7270/Q2HX1C1Z
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor


(Homo sapiens (human))
BDBM50124371
PNG
((E)-3-{4-[3-(3-Phenyl-7-propyl-benzo[d]isoxazol-6-...)
Show SMILES CCCc1c(OCCCOc2ccc(\C=C\C(O)=O)cc2)ccc2c(noc12)-c1ccccc1
Show InChI InChI=1S/C28H27NO5/c1-2-7-23-25(16-15-24-27(29-34-28(23)24)21-8-4-3-5-9-21)33-19-6-18-32-22-13-10-20(11-14-22)12-17-26(30)31/h3-5,8-17H,2,6-7,18-19H2,1H3,(H,30,31)/b17-12+
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/a 254n/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Agonistic activity was determined in COS1 cells transfected with GAL 4-PPAR gamma receptor


Bioorg Med Chem Lett 13: 931-5 (2003)


Article DOI: 10.1016/s0960-894x(02)01029-6
BindingDB Entry DOI: 10.7270/Q2HX1C1Z
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor


(Homo sapiens (human))
BDBM50124394
PNG
(2-Methyl-2-{4-[4-(3-phenyl-7-propyl-benzo[d]isoxaz...)
Show SMILES CCCc1c(OCCCCOc2ccc(OC(C)(C)C(O)=O)cc2)ccc2c(noc12)-c1ccccc1
Show InChI InChI=1S/C30H33NO6/c1-4-10-24-26(18-17-25-27(31-37-28(24)25)21-11-6-5-7-12-21)35-20-9-8-19-34-22-13-15-23(16-14-22)36-30(2,3)29(32)33/h5-7,11-18H,4,8-10,19-20H2,1-3H3,(H,32,33)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/a 2n/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Agonistic activity was determined in COS1 cells transfected with GAL 4-PPAR gamma receptor


Bioorg Med Chem Lett 13: 931-5 (2003)


Article DOI: 10.1016/s0960-894x(02)01029-6
BindingDB Entry DOI: 10.7270/Q2HX1C1Z
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor


(Homo sapiens (Human))
BDBM50124384
PNG
(CHEMBL173494 | {4-[3-(3-Phenyl-7-propyl-benzo[d]is...)
Show SMILES CCCc1c(OCCCOc2ccc(OCC(O)=O)cc2)ccc2c(noc12)-c1ccccc1
Show InChI InChI=1S/C27H27NO6/c1-2-7-22-24(15-14-23-26(28-34-27(22)23)19-8-4-3-5-9-19)32-17-6-16-31-20-10-12-21(13-11-20)33-18-25(29)30/h3-5,8-15H,2,6-7,16-18H2,1H3,(H,29,30)
UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/an/an/a 4n/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
In vitro binding affinity towards human peroxisome proliferator activated receptor gamma (PPAR gamma)


Bioorg Med Chem Lett 13: 931-5 (2003)


Article DOI: 10.1016/s0960-894x(02)01029-6
BindingDB Entry DOI: 10.7270/Q2HX1C1Z
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor


(Homo sapiens (Human))
BDBM50124378
PNG
(2-{4-[3-(3-Phenyl-7-propyl-benzo[d]isoxazol-6-ylox...)
Show SMILES CCCc1c(OCCCOc2ccc(OC(C)C(O)=O)cc2)ccc2c(noc12)-c1ccccc1
Show InChI InChI=1S/C28H29NO6/c1-3-8-23-25(16-15-24-26(29-35-27(23)24)20-9-5-4-6-10-20)33-18-7-17-32-21-11-13-22(14-12-21)34-19(2)28(30)31/h4-6,9-16,19H,3,7-8,17-18H2,1-2H3,(H,30,31)
UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/an/an/a 2n/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
In vitro binding affinity towards human peroxisome proliferator activated receptor delta (PPAR delta)


Bioorg Med Chem Lett 13: 931-5 (2003)


Article DOI: 10.1016/s0960-894x(02)01029-6
BindingDB Entry DOI: 10.7270/Q2HX1C1Z
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha (PPAR alpha)


(Homo sapiens (Human))
BDBM50124386
PNG
(CHEMBL367311 | {4-[4-(3-Phenyl-7-propyl-benzo[d]is...)
Show SMILES CCCc1c(OCCCCOc2ccc(CC(O)=O)cc2)ccc2c(noc12)-c1ccccc1
Show InChI InChI=1S/C28H29NO5/c1-2-8-23-25(16-15-24-27(29-34-28(23)24)21-9-4-3-5-10-21)33-18-7-6-17-32-22-13-11-20(12-14-22)19-26(30)31/h3-5,9-16H,2,6-8,17-19H2,1H3,(H,30,31)
UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/a 8n/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Agonistic activity was determined in COS1 cells transfected with GAL 4-PPAR alpha receptor


Bioorg Med Chem Lett 13: 931-5 (2003)


Article DOI: 10.1016/s0960-894x(02)01029-6
BindingDB Entry DOI: 10.7270/Q2HX1C1Z
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor


(Homo sapiens (human))
BDBM50124380
PNG
(2-Methyl-2-{3-[4-(3-phenyl-7-propyl-benzo[d]isoxaz...)
Show SMILES CCCc1c(OCCCCOc2cccc(OC(C)(C)C(O)=O)c2)ccc2c(noc12)-c1ccccc1
Show InChI InChI=1S/C30H33NO6/c1-4-11-24-26(17-16-25-27(31-37-28(24)25)21-12-6-5-7-13-21)35-19-9-8-18-34-22-14-10-15-23(20-22)36-30(2,3)29(32)33/h5-7,10,12-17,20H,4,8-9,11,18-19H2,1-3H3,(H,32,33)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/a 100n/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Agonistic activity was determined in COS1 cells transfected with GAL 4-PPAR alpha receptor


Bioorg Med Chem Lett 13: 931-5 (2003)


Article DOI: 10.1016/s0960-894x(02)01029-6
BindingDB Entry DOI: 10.7270/Q2HX1C1Z
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor


(Homo sapiens (human))
BDBM50124379
PNG
(2-(4-(3-(3-phenyl-7-propylbenzo[d]isoxazol-6-yloxy...)
Show SMILES CCCc1c(OCCCOc2ccc(CC(O)=O)cc2)ccc2c(noc12)-c1ccccc1
Show InChI InChI=1S/C27H27NO5/c1-2-7-22-24(15-14-23-26(28-33-27(22)23)20-8-4-3-5-9-20)32-17-6-16-31-21-12-10-19(11-13-21)18-25(29)30/h3-5,8-15H,2,6-7,16-18H2,1H3,(H,29,30)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/an/an/a 194n/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Agonistic activity was determined in COS1 cells transfected with GAL 4-PPAR alpha receptor


Bioorg Med Chem Lett 13: 931-5 (2003)


Article DOI: 10.1016/s0960-894x(02)01029-6
BindingDB Entry DOI: 10.7270/Q2HX1C1Z
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor


(Homo sapiens (human))
BDBM28681
PNG
(5-[(4-{2-[methyl(pyridin-2-yl)amino]ethoxy}phenyl)...)
Show SMILES CN(CCOc1ccc(Cc2sc(=O)[nH]c2O)cc1)c1ccccn1
Show InChI InChI=1S/C18H19N3O3S/c1-21(16-4-2-3-9-19-16)10-11-24-14-7-5-13(6-8-14)12-15-17(22)20-18(23)25-15/h2-9,22H,10-12H2,1H3,(H,20,23)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/an/an/a 21n/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
In vitro binding affinity towards human peroxisome proliferator activated receptor alpha (PPAR alpha)


Bioorg Med Chem Lett 13: 931-5 (2003)


Article DOI: 10.1016/s0960-894x(02)01029-6
BindingDB Entry DOI: 10.7270/Q2HX1C1Z
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor


(Homo sapiens (human))
BDBM50124385
PNG
(3-[4-(3-Phenyl-7-propyl-benzo[d]isoxazol-6-yloxy)-...)
Show SMILES CCCc1c(OCCCCOc2cccc(c2)C(O)=O)ccc2c(noc12)-c1ccccc1
Show InChI InChI=1S/C27H27NO5/c1-2-9-22-24(15-14-23-25(28-33-26(22)23)19-10-4-3-5-11-19)32-17-7-6-16-31-21-13-8-12-20(18-21)27(29)30/h3-5,8,10-15,18H,2,6-7,9,16-17H2,1H3,(H,29,30)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/a 193n/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Agonistic activity was determined in COS1 cells transfected with GAL 4-PPAR gamma receptor


Bioorg Med Chem Lett 13: 931-5 (2003)


Article DOI: 10.1016/s0960-894x(02)01029-6
BindingDB Entry DOI: 10.7270/Q2HX1C1Z
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor


(Homo sapiens (human))
BDBM50124387
PNG
(2-Methyl-2-{3-[4-(3-phenyl-7-propyl-benzo[d]isoxaz...)
Show SMILES CCCc1c(OCCCCOc2cccc(c2)C(C)(C)C(O)=O)ccc2c(noc12)-c1ccccc1
Show InChI InChI=1S/C30H33NO5/c1-4-11-24-26(17-16-25-27(31-36-28(24)25)21-12-6-5-7-13-21)35-19-9-8-18-34-23-15-10-14-22(20-23)30(2,3)29(32)33/h5-7,10,12-17,20H,4,8-9,11,18-19H2,1-3H3,(H,32,33)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/a 52n/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Agonistic activity was determined in COS1 cells transfected with GAL 4-PPAR gamma receptor


Bioorg Med Chem Lett 13: 931-5 (2003)


Article DOI: 10.1016/s0960-894x(02)01029-6
BindingDB Entry DOI: 10.7270/Q2HX1C1Z
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor


(Homo sapiens (Human))
BDBM50124389
PNG
(2,2-Dimethyl-3-{4-[4-(3-phenyl-7-propyl-benzo[d]is...)
Show SMILES CCCc1c(OCCCCOc2ccc(CC(C)(C)C(O)=O)cc2)ccc2c(noc12)-c1ccccc1
Show InChI InChI=1S/C31H35NO5/c1-4-10-25-27(18-17-26-28(32-37-29(25)26)23-11-6-5-7-12-23)36-20-9-8-19-35-24-15-13-22(14-16-24)21-31(2,3)30(33)34/h5-7,11-18H,4,8-10,19-21H2,1-3H3,(H,33,34)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/a 860n/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Agonistic activity was determined in COS1 cells transfected with GAL 4-PPAR delta receptor


Bioorg Med Chem Lett 13: 931-5 (2003)


Article DOI: 10.1016/s0960-894x(02)01029-6
BindingDB Entry DOI: 10.7270/Q2HX1C1Z
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha (PPAR alpha)


(Homo sapiens (Human))
BDBM50124369
PNG
(CHEMBL367019 | {3-Chloro-4-[3-(3-phenyl-7-propyl-b...)
Show SMILES CCCc1c(OCCCSc2ccc(CC(O)=O)cc2Cl)ccc2c(noc12)-c1ccccc1
Show InChI InChI=1S/C27H26ClNO4S/c1-2-7-20-23(12-11-21-26(29-33-27(20)21)19-8-4-3-5-9-19)32-14-6-15-34-24-13-10-18(16-22(24)28)17-25(30)31/h3-5,8-13,16H,2,6-7,14-15,17H2,1H3,(H,30,31)
UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/an/an/a 3n/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Agonistic activity was determined in COS1 cells transfected with GAL 4-PPAR alpha receptor


Bioorg Med Chem Lett 13: 931-5 (2003)


Article DOI: 10.1016/s0960-894x(02)01029-6
BindingDB Entry DOI: 10.7270/Q2HX1C1Z
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor


(Homo sapiens (Human))
BDBM50124376
PNG
(4-{4-[3-(3-Phenyl-7-propyl-benzo[d]isoxazol-6-ylox...)
Show SMILES CCCc1c(OCCCOc2ccc(CCCC(O)=O)cc2)ccc2c(noc12)-c1ccccc1
Show InChI InChI=1S/C29H31NO5/c1-2-8-24-26(18-17-25-28(30-35-29(24)25)22-10-4-3-5-11-22)34-20-7-19-33-23-15-13-21(14-16-23)9-6-12-27(31)32/h3-5,10-11,13-18H,2,6-9,12,19-20H2,1H3,(H,31,32)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/a 183n/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Agonistic activity was determined in COS1 cells transfected with GAL 4-PPAR gamma receptor


Bioorg Med Chem Lett 13: 931-5 (2003)


Article DOI: 10.1016/s0960-894x(02)01029-6
BindingDB Entry DOI: 10.7270/Q2HX1C1Z
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor


(Homo sapiens (Human))
BDBM50124393
PNG
(4-{4-[2-(3-Phenyl-7-propyl-benzo[d]isoxazol-6-ylox...)
Show SMILES CCCc1c(OCCOc2ccc(CCCC(O)=O)cc2)ccc2c(noc12)-c1ccccc1
Show InChI InChI=1S/C28H29NO5/c1-2-7-23-25(17-16-24-27(29-34-28(23)24)21-9-4-3-5-10-21)33-19-18-32-22-14-12-20(13-15-22)8-6-11-26(30)31/h3-5,9-10,12-17H,2,6-8,11,18-19H2,1H3,(H,30,31)
UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/a 33n/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Agonistic activity was determined in COS1 cells transfected with GAL 4-PPAR gamma receptor


Bioorg Med Chem Lett 13: 931-5 (2003)


Article DOI: 10.1016/s0960-894x(02)01029-6
BindingDB Entry DOI: 10.7270/Q2HX1C1Z
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor


(Homo sapiens (human))
BDBM50124376
PNG
(4-{4-[3-(3-Phenyl-7-propyl-benzo[d]isoxazol-6-ylox...)
Show SMILES CCCc1c(OCCCOc2ccc(CCCC(O)=O)cc2)ccc2c(noc12)-c1ccccc1
Show InChI InChI=1S/C29H31NO5/c1-2-8-24-26(18-17-25-28(30-35-29(24)25)22-10-4-3-5-11-22)34-20-7-19-33-23-15-13-21(14-16-23)9-6-12-27(31)32/h3-5,10-11,13-18H,2,6-9,12,19-20H2,1H3,(H,31,32)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/a 156n/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
In vitro binding affinity towards human peroxisome proliferator activated receptor delta (PPAR delta)


Bioorg Med Chem Lett 13: 931-5 (2003)


Article DOI: 10.1016/s0960-894x(02)01029-6
BindingDB Entry DOI: 10.7270/Q2HX1C1Z
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha (PPAR alpha)


(Homo sapiens (Human))
BDBM50124376
PNG
(4-{4-[3-(3-Phenyl-7-propyl-benzo[d]isoxazol-6-ylox...)
Show SMILES CCCc1c(OCCCOc2ccc(CCCC(O)=O)cc2)ccc2c(noc12)-c1ccccc1
Show InChI InChI=1S/C29H31NO5/c1-2-8-24-26(18-17-25-28(30-35-29(24)25)22-10-4-3-5-11-22)34-20-7-19-33-23-15-13-21(14-16-23)9-6-12-27(31)32/h3-5,10-11,13-18H,2,6-9,12,19-20H2,1H3,(H,31,32)
UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/a 3n/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Agonistic activity was determined in COS1 cells transfected with GAL 4-PPAR alpha receptor


Bioorg Med Chem Lett 13: 931-5 (2003)


Article DOI: 10.1016/s0960-894x(02)01029-6
BindingDB Entry DOI: 10.7270/Q2HX1C1Z
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor


(Homo sapiens (human))
BDBM50124375
PNG
(2-Methyl-2-{4-[4-(3-phenyl-7-propyl-benzo[d]isoxaz...)
Show SMILES CCCc1c(OCCCCOc2ccc(cc2)C(C)(C)C(O)=O)ccc2c(noc12)-c1ccccc1
Show InChI InChI=1S/C30H33NO5/c1-4-10-24-26(18-17-25-27(31-36-28(24)25)21-11-6-5-7-12-21)35-20-9-8-19-34-23-15-13-22(14-16-23)30(2,3)29(32)33/h5-7,11-18H,4,8-10,19-20H2,1-3H3,(H,32,33)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/a 10n/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
In vitro binding affinity towards human peroxisome proliferator activated receptor delta (PPAR delta)


Bioorg Med Chem Lett 13: 931-5 (2003)


Article DOI: 10.1016/s0960-894x(02)01029-6
BindingDB Entry DOI: 10.7270/Q2HX1C1Z
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor


(Homo sapiens (Human))
BDBM50124372
PNG
((E)-3-{4-[4-(3-Phenyl-7-propyl-benzo[d]isoxazol-6-...)
Show SMILES CCCc1c(OCCCCOc2ccc(\C=C\C(O)=O)cc2)ccc2c(noc12)-c1ccccc1
Show InChI InChI=1S/C29H29NO5/c1-2-8-24-26(17-16-25-28(30-35-29(24)25)22-9-4-3-5-10-22)34-20-7-6-19-33-23-14-11-21(12-15-23)13-18-27(31)32/h3-5,9-18H,2,6-8,19-20H2,1H3,(H,31,32)/b18-13+
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/a 640n/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Agonistic activity was determined in COS1 cells transfected with GAL 4-PPAR gamma receptor


Bioorg Med Chem Lett 13: 931-5 (2003)


Article DOI: 10.1016/s0960-894x(02)01029-6
BindingDB Entry DOI: 10.7270/Q2HX1C1Z
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor


(Homo sapiens (human))
BDBM50124384
PNG
(CHEMBL173494 | {4-[3-(3-Phenyl-7-propyl-benzo[d]is...)
Show SMILES CCCc1c(OCCCOc2ccc(OCC(O)=O)cc2)ccc2c(noc12)-c1ccccc1
Show InChI InChI=1S/C27H27NO6/c1-2-7-22-24(15-14-23-26(28-34-27(22)23)19-8-4-3-5-9-19)32-17-6-16-31-20-10-12-21(13-11-20)33-18-25(29)30/h3-5,8-15H,2,6-7,16-18H2,1H3,(H,29,30)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/an/an/a 75n/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Agonistic activity was determined in COS1 cells transfected with GAL 4-PPAR gamma receptor


Bioorg Med Chem Lett 13: 931-5 (2003)


Article DOI: 10.1016/s0960-894x(02)01029-6
BindingDB Entry DOI: 10.7270/Q2HX1C1Z
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor


(Homo sapiens (Human))
BDBM50124370
PNG
(CHEMBL173409 | {3-[4-(3-Phenyl-7-propyl-benzo[d]is...)
Show SMILES CCCc1c(OCCCCOc2cccc(OCC(O)=O)c2)ccc2c(noc12)-c1ccccc1
Show InChI InChI=1S/C28H29NO6/c1-2-9-23-25(15-14-24-27(29-35-28(23)24)20-10-4-3-5-11-20)33-17-7-6-16-32-21-12-8-13-22(18-21)34-19-26(30)31/h3-5,8,10-15,18H,2,6-7,9,16-17,19H2,1H3,(H,30,31)
UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/an/an/a 248n/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Agonistic activity was determined in COS1 cells transfected with GAL 4-PPAR alpha receptor


Bioorg Med Chem Lett 13: 931-5 (2003)


Article DOI: 10.1016/s0960-894x(02)01029-6
BindingDB Entry DOI: 10.7270/Q2HX1C1Z
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha (PPAR alpha)


(Homo sapiens (Human))
BDBM50124392
PNG
(2-{4-[4-(3-Phenyl-7-propyl-benzo[d]isoxazol-6-ylox...)
Show SMILES CCCc1c(OCCCCOc2ccc(OC(C)C(O)=O)cc2)ccc2c(noc12)-c1ccccc1
Show InChI InChI=1S/C29H31NO6/c1-3-9-24-26(17-16-25-27(30-36-28(24)25)21-10-5-4-6-11-21)34-19-8-7-18-33-22-12-14-23(15-13-22)35-20(2)29(31)32/h4-6,10-17,20H,3,7-9,18-19H2,1-2H3,(H,31,32)
UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/an/an/a 10n/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Agonistic activity was determined in COS1 cells transfected with GAL 4-PPAR alpha receptor


Bioorg Med Chem Lett 13: 931-5 (2003)


Article DOI: 10.1016/s0960-894x(02)01029-6
BindingDB Entry DOI: 10.7270/Q2HX1C1Z
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha (PPAR alpha)


(Homo sapiens (Human))
BDBM50124380
PNG
(2-Methyl-2-{3-[4-(3-phenyl-7-propyl-benzo[d]isoxaz...)
Show SMILES CCCc1c(OCCCCOc2cccc(OC(C)(C)C(O)=O)c2)ccc2c(noc12)-c1ccccc1
Show InChI InChI=1S/C30H33NO6/c1-4-11-24-26(17-16-25-27(31-37-28(24)25)21-12-6-5-7-13-21)35-19-9-8-18-34-22-14-10-15-23(20-22)36-30(2,3)29(32)33/h5-7,10,12-17,20H,4,8-9,11,18-19H2,1-3H3,(H,32,33)
UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/a 92n/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Agonistic activity was determined in COS1 cells transfected with GAL 4-PPAR alpha receptor


Bioorg Med Chem Lett 13: 931-5 (2003)


Article DOI: 10.1016/s0960-894x(02)01029-6
BindingDB Entry DOI: 10.7270/Q2HX1C1Z
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor


(Homo sapiens (Human))
BDBM50124389
PNG
(2,2-Dimethyl-3-{4-[4-(3-phenyl-7-propyl-benzo[d]is...)
Show SMILES CCCc1c(OCCCCOc2ccc(CC(C)(C)C(O)=O)cc2)ccc2c(noc12)-c1ccccc1
Show InChI InChI=1S/C31H35NO5/c1-4-10-25-27(18-17-26-28(32-37-29(25)26)23-11-6-5-7-12-23)36-20-9-8-19-35-24-15-13-22(14-16-24)21-31(2,3)30(33)34/h5-7,11-18H,4,8-10,19-21H2,1-3H3,(H,33,34)
UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/a 4n/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
In vitro binding affinity towards human peroxisome proliferator activated receptor gamma (PPAR gamma)


Bioorg Med Chem Lett 13: 931-5 (2003)


Article DOI: 10.1016/s0960-894x(02)01029-6
BindingDB Entry DOI: 10.7270/Q2HX1C1Z
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor


(Homo sapiens (human))
BDBM50124382
PNG
(3-Methyl-3-{4-[4-(3-phenyl-7-propyl-benzo[d]isoxaz...)
Show SMILES CCCc1c(OCCCCOc2ccc(cc2)C(C)(C)CC(O)=O)ccc2c(noc12)-c1ccccc1
Show InChI InChI=1S/C31H35NO5/c1-4-10-25-27(18-17-26-29(32-37-30(25)26)22-11-6-5-7-12-22)36-20-9-8-19-35-24-15-13-23(14-16-24)31(2,3)21-28(33)34/h5-7,11-18H,4,8-10,19-21H2,1-3H3,(H,33,34)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/a 37n/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Agonistic activity was determined in COS1 cells transfected with GAL 4-PPAR alpha receptor


Bioorg Med Chem Lett 13: 931-5 (2003)


Article DOI: 10.1016/s0960-894x(02)01029-6
BindingDB Entry DOI: 10.7270/Q2HX1C1Z
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor


(Homo sapiens (human))
BDBM50124392
PNG
(2-{4-[4-(3-Phenyl-7-propyl-benzo[d]isoxazol-6-ylox...)
Show SMILES CCCc1c(OCCCCOc2ccc(OC(C)C(O)=O)cc2)ccc2c(noc12)-c1ccccc1
Show InChI InChI=1S/C29H31NO6/c1-3-9-24-26(17-16-25-27(30-36-28(24)25)21-10-5-4-6-11-21)34-19-8-7-18-33-22-12-14-23(15-13-22)35-20(2)29(31)32/h4-6,10-17,20H,3,7-9,18-19H2,1-2H3,(H,31,32)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/an/an/a 16n/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Agonistic activity was determined in COS1 cells transfected with GAL 4-PPAR gamma receptor


Bioorg Med Chem Lett 13: 931-5 (2003)


Article DOI: 10.1016/s0960-894x(02)01029-6
BindingDB Entry DOI: 10.7270/Q2HX1C1Z
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor


(Homo sapiens (human))
BDBM50124369
PNG
(CHEMBL367019 | {3-Chloro-4-[3-(3-phenyl-7-propyl-b...)
Show SMILES CCCc1c(OCCCSc2ccc(CC(O)=O)cc2Cl)ccc2c(noc12)-c1ccccc1
Show InChI InChI=1S/C27H26ClNO4S/c1-2-7-20-23(12-11-21-26(29-33-27(20)21)19-8-4-3-5-9-19)32-14-6-15-34-24-13-10-18(16-22(24)28)17-25(30)31/h3-5,8-13,16H,2,6-7,14-15,17H2,1H3,(H,30,31)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/an/an/a 4n/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Agonistic activity was determined in COS1 cells transfected with GAL 4-PPAR gamma receptor


Bioorg Med Chem Lett 13: 931-5 (2003)


Article DOI: 10.1016/s0960-894x(02)01029-6
BindingDB Entry DOI: 10.7270/Q2HX1C1Z
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor


(Homo sapiens (human))
BDBM50124378
PNG
(2-{4-[3-(3-Phenyl-7-propyl-benzo[d]isoxazol-6-ylox...)
Show SMILES CCCc1c(OCCCOc2ccc(OC(C)C(O)=O)cc2)ccc2c(noc12)-c1ccccc1
Show InChI InChI=1S/C28H29NO6/c1-3-8-23-25(16-15-24-26(29-35-27(23)24)20-9-5-4-6-10-20)33-18-7-17-32-21-11-13-22(14-12-21)34-19(2)28(30)31/h4-6,9-16,19H,3,7-8,17-18H2,1-2H3,(H,30,31)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/an/an/a 27n/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
In vitro binding affinity towards human peroxisome proliferator activated receptor alpha (PPAR alpha)


Bioorg Med Chem Lett 13: 931-5 (2003)


Article DOI: 10.1016/s0960-894x(02)01029-6
BindingDB Entry DOI: 10.7270/Q2HX1C1Z
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha (PPAR alpha)


(Homo sapiens (Human))
BDBM33283
PNG
((3-{4-[(3-phenyl-7-propyl-1,2-benzisoxazol-6-yl)ox...)
Show SMILES CCCc1c(OCCCCOc2cccc(CC(O)=O)c2)ccc2c(noc12)-c1ccccc1
Show InChI InChI=1S/C28H29NO5/c1-2-9-23-25(15-14-24-27(29-34-28(23)24)21-11-4-3-5-12-21)33-17-7-6-16-32-22-13-8-10-20(18-22)19-26(30)31/h3-5,8,10-15,18H,2,6-7,9,16-17,19H2,1H3,(H,30,31)
UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/an/an/a 5n/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Agonistic activity was determined in COS1 cells transfected with GAL 4-PPAR alpha receptor


Bioorg Med Chem Lett 13: 931-5 (2003)


Article DOI: 10.1016/s0960-894x(02)01029-6
BindingDB Entry DOI: 10.7270/Q2HX1C1Z
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor


(Homo sapiens (Human))
BDBM50124374
PNG
(3-{4-[4-(3-Phenyl-7-propyl-benzo[d]isoxazol-6-ylox...)
Show SMILES CCCc1c(OCCCCOc2ccc(CCC(O)=O)cc2)ccc2c(noc12)-c1ccccc1
Show InChI InChI=1S/C29H31NO5/c1-2-8-24-26(17-16-25-28(30-35-29(24)25)22-9-4-3-5-10-22)34-20-7-6-19-33-23-14-11-21(12-15-23)13-18-27(31)32/h3-5,9-12,14-17H,2,6-8,13,18-20H2,1H3,(H,31,32)
UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/an/an/a 429n/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Agonistic activity was determined in COS1 cells transfected with GAL 4-PPAR gamma receptor


Bioorg Med Chem Lett 13: 931-5 (2003)


Article DOI: 10.1016/s0960-894x(02)01029-6
BindingDB Entry DOI: 10.7270/Q2HX1C1Z
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor delta (PPAR delta)


(Homo sapiens (Human))
BDBM50124394
PNG
(2-Methyl-2-{4-[4-(3-phenyl-7-propyl-benzo[d]isoxaz...)
Show SMILES CCCc1c(OCCCCOc2ccc(OC(C)(C)C(O)=O)cc2)ccc2c(noc12)-c1ccccc1
Show InChI InChI=1S/C30H33NO6/c1-4-10-24-26(18-17-25-27(31-37-28(24)25)21-11-6-5-7-12-21)35-20-9-8-19-34-22-13-15-23(16-14-22)36-30(2,3)29(32)33/h5-7,11-18H,4,8-10,19-20H2,1-3H3,(H,32,33)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/a 172n/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Agonistic activity was determined in COS1 cells transfected with GAL 4-PPAR delta receptor


Bioorg Med Chem Lett 13: 931-5 (2003)


Article DOI: 10.1016/s0960-894x(02)01029-6
BindingDB Entry DOI: 10.7270/Q2HX1C1Z
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor


(Homo sapiens (human))
BDBM50124389
PNG
(2,2-Dimethyl-3-{4-[4-(3-phenyl-7-propyl-benzo[d]is...)
Show SMILES CCCc1c(OCCCCOc2ccc(CC(C)(C)C(O)=O)cc2)ccc2c(noc12)-c1ccccc1
Show InChI InChI=1S/C31H35NO5/c1-4-10-25-27(18-17-26-28(32-37-29(25)26)23-11-6-5-7-12-23)36-20-9-8-19-35-24-15-13-22(14-16-24)21-31(2,3)30(33)34/h5-7,11-18H,4,8-10,19-21H2,1-3H3,(H,33,34)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/a 20n/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Agonistic activity was determined in COS1 cells transfected with GAL 4-PPAR gamma receptor


Bioorg Med Chem Lett 13: 931-5 (2003)


Article DOI: 10.1016/s0960-894x(02)01029-6
BindingDB Entry DOI: 10.7270/Q2HX1C1Z
More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor


(Homo sapiens (Human))
BDBM50124382
PNG
(3-Methyl-3-{4-[4-(3-phenyl-7-propyl-benzo[d]isoxaz...)
Show SMILES CCCc1c(OCCCCOc2ccc(cc2)C(C)(C)CC(O)=O)ccc2c(noc12)-c1ccccc1
Show InChI InChI=1S/C31H35NO5/c1-4-10-25-27(18-17-26-29(32-37-30(25)26)22-11-6-5-7-12-22)36-20-9-8-19-35-24-15-13-23(14-16-24)31(2,3)21-28(33)34/h5-7,11-18H,4,8-10,19-21H2,1-3H3,(H,33,34)
UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/a 53n/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
In vitro binding affinity towards human peroxisome proliferator activated receptor delta (PPAR delta)


Bioorg Med Chem Lett 13: 931-5 (2003)


Article DOI: 10.1016/s0960-894x(02)01029-6
BindingDB Entry DOI: 10.7270/Q2HX1C1Z
More data for this
Ligand-Target Pair
* indicates data uncertainty>20%