Compile Data Set for Download or QSAR
maximum 50k data
Found 14 Enz. Inhib. hit(s) with all data for entry = 50013224
Target72 kDa type IV collagenase(Homo sapiens (Human))
Université

Curated by ChEMBL
LigandPNGBDBM50062351((R)-N*4*-Hydroxy-N*1*-[(S)-2-(1H-indol-3-yl)-1-met...)
Affinity DataIC50:  0.400nMAssay Description:Inhibition of Matrix metalloproteinase-2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Université

Curated by ChEMBL
LigandPNGBDBM50062351((R)-N*4*-Hydroxy-N*1*-[(S)-2-(1H-indol-3-yl)-1-met...)
Affinity DataIC50:  3nMAssay Description:Inhibition of matrix metalloproteinase-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Université

Curated by ChEMBL
LigandPNGBDBM50127864((R)-3-[2-(1H-Indol-3-yl)-1-methylcarbamoyl-ethylca...)
Affinity DataIC50:  6nMAssay Description:Inhibition of matrix metalloproteinase-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Université

Curated by ChEMBL
LigandPNGBDBM50127863((R)-2-[(4-methylphenyl)sulfonyl]Hydrazinocarbonylm...)
Affinity DataIC50: >10nMAssay Description:Inhibition of matrix metalloproteinase-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Université

Curated by ChEMBL
LigandPNGBDBM50127864((R)-3-[2-(1H-Indol-3-yl)-1-methylcarbamoyl-ethylca...)
Affinity DataIC50:  20nMAssay Description:Inhibition of Matrix metalloproteinase-2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Université

Curated by ChEMBL
LigandPNGBDBM50127863((R)-2-[(4-methylphenyl)sulfonyl]Hydrazinocarbonylm...)
Affinity DataIC50:  30nMAssay Description:Inhibition of Matrix metalloproteinase-2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Université

Curated by ChEMBL
LigandPNGBDBM50127867(2-(R)-1-Hydrazinocarbonylmethyl-4-methyl-pentanoic...)
Affinity DataIC50:  50nMAssay Description:Inhibition of matrix metalloproteinase-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Université

Curated by ChEMBL
LigandPNGBDBM50127862((R)-N*1*-[2-(1H-Indol-3-yl)-1-methylcarbamoyl-ethy...)
Affinity DataIC50:  50nMAssay Description:Inhibition of Matrix metalloproteinase-2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Université

Curated by ChEMBL
LigandPNGBDBM50127862((R)-N*1*-[2-(1H-Indol-3-yl)-1-methylcarbamoyl-ethy...)
Affinity DataIC50:  60nMAssay Description:Inhibition of matrix metalloproteinase-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Université

Curated by ChEMBL
LigandPNGBDBM50127865(4-Methyl-2-((R)-2-oxo-2-pyridin-2-yl-ethyl)-pentan...)
Affinity DataIC50:  180nMAssay Description:Inhibition of Matrix metalloproteinase-2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Université

Curated by ChEMBL
LigandPNGBDBM50127866(4-Methyl-2-[(R)-2-oxo-2-(1H-pyrrol-2-yl)-ethyl]-pe...)
Affinity DataIC50:  540nMAssay Description:Inhibition of Matrix metalloproteinase-2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Université

Curated by ChEMBL
LigandPNGBDBM50127867(2-(R)-1-Hydrazinocarbonylmethyl-4-methyl-pentanoic...)
Affinity DataIC50:  550nMAssay Description:Inhibition of Matrix metalloproteinase-2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Université

Curated by ChEMBL
LigandPNGBDBM50127865(4-Methyl-2-((R)-2-oxo-2-pyridin-2-yl-ethyl)-pentan...)
Affinity DataIC50:  730nMAssay Description:Inhibition of matrix metalloproteinase-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Université

Curated by ChEMBL
LigandPNGBDBM50127866(4-Methyl-2-[(R)-2-oxo-2-(1H-pyrrol-2-yl)-ethyl]-pe...)
Affinity DataIC50:  860nMAssay Description:Inhibition of matrix metalloproteinase-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed