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Found 29 Enz. Inhib. hit(s) with all data for entry = 50013273
TargetInsulin-like growth factor-binding protein 3(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50106431(1-(3,4-Dihydroxy-benzoyl)-6,7-dihydroxy-isoquinoli...)
Affinity DataKi:  5.60nMAssay Description:Ability to displace Insulin-Like Growth Factor (IGF-I) from its binding to human insulin-like growth factor binding protein 3 (hIGFBP-3)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor-binding protein 3(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50128442(1-[4-(3,5-Dichloro-phenoxy)-3-fluoro-benzoyl]-6,7-...)
Affinity DataKi:  9nMAssay Description:Ability to displace Insulin-Like Growth Factor (IGF-I) from its binding to human insulin-like growth factor binding protein 3 (hIGFBP-3)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor-binding protein 3(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50128432(1-(3-Fluoro-4-p-tolyloxy-benzoyl)-6,7-dihydroxy-is...)
Affinity DataKi:  9.40nMAssay Description:Ability to displace Insulin-Like Growth Factor (IGF-I) from its binding to human insulin-like growth factor binding protein 3 (hIGFBP-3)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor-binding protein 3(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50128452(6,7-Dihydroxy-1-[hydroxy-(2,4,6-trimethyl-phenyl)-...)
Affinity DataKi:  11nMAssay Description:Ability to displace Insulin-Like Growth Factor (IGF-I) from its binding to human insulin-like growth factor binding protein 3 (hIGFBP-3)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor-binding protein 3(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50128450(1-[4-(3-Chloro-phenoxy)-3-fluoro-benzoyl]-6,7-dihy...)
Affinity DataKi:  11nMAssay Description:Ability to displace Insulin-Like Growth Factor (IGF-I) from its binding to human insulin-like growth factor binding protein 3 (hIGFBP-3)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor-binding protein 3(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50128451(1-[4-(3,4-Dichloro-phenoxy)-3-fluoro-benzoyl]-6,7-...)
Affinity DataKi:  12nMAssay Description:Ability to displace Insulin-Like Growth Factor (IGF-I) from its binding to human insulin-like growth factor binding protein 3 (hIGFBP-3)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor-binding protein 3(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50128430(6,7-Dihydroxy-1-[hydroxy-(4-trifluoromethyl-phenyl...)
Affinity DataKi:  18nMAssay Description:Ability to displace Insulin-Like Growth Factor (IGF-I) from its binding to human insulin-like growth factor binding protein 3 (hIGFBP-3)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor-binding protein 3(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50128454(1-[4-(4-Chloro-phenoxy)-3-fluoro-benzoyl]-6,7-dihy...)
Affinity DataKi:  20nMAssay Description:Ability to displace Insulin-Like Growth Factor (IGF-I) from its binding to human insulin-like growth factor binding protein 3 (hIGFBP-3)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor-binding protein 3(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50128433(1-[(3-Fluoro-phenyl)-hydroxy-methyl]-6,7-dihydroxy...)
Affinity DataKi:  24nMAssay Description:Ability to displace Insulin-Like Growth Factor (IGF-I) from its binding to human insulin-like growth factor binding protein 3 (hIGFBP-3)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor-binding protein 3(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50128438(1-[(2-Chloro-phenyl)-hydroxy-methyl]-6,7-dihydroxy...)
Affinity DataKi:  25nMAssay Description:Ability to displace Insulin-Like Growth Factor (IGF-I) from its binding to human insulin-like growth factor binding protein 3 (hIGFBP-3)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor-binding protein 3(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50128447(1-(3,4-Dichloro-benzoyl)-6,7-dihydroxy-isoquinolin...)
Affinity DataKi:  29nMAssay Description:Ability to displace Insulin-Like Growth Factor (IGF-I) from its binding to human insulin-like growth factor binding protein 3 (hIGFBP-3)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor-binding protein 3(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50128434(1-[4-(4-Chloro-phenylsulfanyl)-3-fluoro-benzoyl]-6...)
Affinity DataKi:  31nMAssay Description:Ability to displace Insulin-Like Growth Factor (IGF-I) from its binding to human insulin-like growth factor binding protein 3 (hIGFBP-3)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor-binding protein 3(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50128446(6,7-Dihydroxy-1-(4-nitro-benzoyl)-isoquinoline-3-c...)
Affinity DataKi:  32nMAssay Description:Ability to displace Insulin-Like Growth Factor (IGF-I) from its binding to human insulin-like growth factor binding protein 3 (hIGFBP-3)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor-binding protein 3(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50128443(6,7-Dihydroxy-1-[hydroxy-(4-phenoxy-phenyl)-methyl...)
Affinity DataKi:  32nMAssay Description:Ability to displace Insulin-Like Growth Factor (IGF-I) from its binding to human insulin-like growth factor binding protein 3 (hIGFBP-3)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor-binding protein 3(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50128436(1-[4-(Biphenyl-4-yloxy)-3-fluoro-benzoyl]-6,7-dihy...)
Affinity DataKi:  32nMAssay Description:Ability to displace Insulin-Like Growth Factor (IGF-I) from its binding to human insulin-like growth factor binding protein 3 (hIGFBP-3)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor-binding protein 3(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50128431(1-[3-Fluoro-4-(4-trifluoromethyl-phenoxy)-benzoyl]...)
Affinity DataKi:  32nMAssay Description:Ability to displace Insulin-Like Growth Factor (IGF-I) from its binding to human insulin-like growth factor binding protein 3 (hIGFBP-3)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor-binding protein 3(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50128437(6,7-Dihydroxy-1-(4-trifluoromethyl-benzoyl)-isoqui...)
Affinity DataKi:  38nMAssay Description:Ability to displace Insulin-Like Growth Factor (IGF-I) from its binding to human insulin-like growth factor binding protein 3 (hIGFBP-3)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor-binding protein 3(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50128455(1-(3,4-Difluoro-benzoyl)-6,7-dihydroxy-isoquinolin...)
Affinity DataKi:  51nMAssay Description:Ability to displace Insulin-Like Growth Factor (IGF-I) from its binding to human insulin-like growth factor binding protein 3 (hIGFBP-3)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor-binding protein 3(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50128444(6-Amino-1-(3,4-dihydroxy-benzoyl)-7-hydroxy-isoqui...)
Affinity DataKi:  60nMAssay Description:Ability to displace Insulin-Like Growth Factor (IGF-I) from its binding to human insulin-like growth factor binding protein 3 (hIGFBP-3)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor-binding protein 3(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50128440(1-[4-(2-Ethyl-hexylamino)-3-fluoro-benzoyl]-6,7-di...)
Affinity DataKi:  62nMAssay Description:Ability to displace Insulin-Like Growth Factor (IGF-I) from its binding to human insulin-like growth factor binding protein 3 (hIGFBP-3)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor-binding protein 3(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50106438(1-(Benzo[1,3]dioxole-5-carbonyl)-6,7-dihydroxy-iso...)
Affinity DataKi:  70nMAssay Description:Ability to displace Insulin-Like Growth Factor (IGF-I) from its binding to human insulin-like growth factor binding protein 3 (hIGFBP-3)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor-binding protein 3(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50128439(1-Benzo[1,3]dioxol-5-ylmethyl-6,7-dihydroxy-isoqui...)
Affinity DataKi:  72nMAssay Description:Ability to displace Insulin-Like Growth Factor (IGF-I) from its binding to human insulin-like growth factor binding protein 3 (hIGFBP-3)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor-binding protein 3(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50128435(6,7-Dihydroxy-1-(2,4,6-trimethyl-benzoyl)-isoquino...)
Affinity DataKi:  100nMAssay Description:Ability to displace Insulin-Like Growth Factor (IGF-I) from its binding to human insulin-like growth factor binding protein 3 (hIGFBP-3)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor-binding protein 3(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50128449(1-(3-Fluoro-benzoyl)-6,7-dihydroxy-isoquinoline-3-...)
Affinity DataKi:  110nMAssay Description:Ability to displace Insulin-Like Growth Factor (IGF-I) from its binding to human insulin-like growth factor binding protein 3 (hIGFBP-3)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor-binding protein 3(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50128441(6,7-Dihydroxy-1-(4-methanesulfonylamino-benzoyl)-i...)
Affinity DataKi:  110nMAssay Description:Ability to displace Insulin-Like Growth Factor (IGF-I) from its binding to human insulin-like growth factor binding protein 3 (hIGFBP-3)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor-binding protein 3(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50128453(1-(2-Chloro-benzoyl)-6,7-dihydroxy-isoquinoline-3-...)
Affinity DataKi:  110nMAssay Description:Ability to displace Insulin-Like Growth Factor (IGF-I) from its binding to human insulin-like growth factor binding protein 3 (hIGFBP-3)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor-binding protein 3(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50128448(1-(4-Amino-benzoyl)-6,7-dihydroxy-isoquinoline-3-c...)
Affinity DataKi:  130nMAssay Description:Ability to displace Insulin-Like Growth Factor (IGF-I) from its binding to human insulin-like growth factor binding protein 3 (hIGFBP-3)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor-binding protein 3(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50128445(6-Amino-1-(benzo[1,3]dioxole-5-carbonyl)-7-hydroxy...)
Affinity DataKi:  850nMAssay Description:Ability to displace Insulin-Like Growth Factor (IGF-I) from its binding to human insulin-like growth factor binding protein 3 (hIGFBP-3)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor-binding protein 3(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50128429(1-(Benzo[1,3]dioxole-5-carbonyl)-7-hydroxy-6-metha...)
Affinity DataKi: >1.00E+4nMAssay Description:Ability to displace Insulin-Like Growth Factor (IGF-I) from its binding to human insulin-like growth factor binding protein 3 (hIGFBP-3)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed