Compile Data Set for Download or QSAR
maximum 50k data
Found 39 Enz. Inhib. hit(s) with all data for entry = 50013382
TargetProthrombin(Homo sapiens (Human))
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50129977(4-[7-(1,1-Dimethyl-2-oxo-2-pyrrolidin-1-yl-ethyl)-...)
Affinity DataIC50:  5nMAssay Description:Inhibition of human thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50129957(2-[2-(4-Carbamimidoyl-phenoxy)-4-methyl-quinolin-7...)
Affinity DataIC50:  6nMAssay Description:Inhibition of human thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50129976(4-{4-Methyl-3-oxo-7-[1-(pyrrolidine-1-carbonyl)-cy...)
Affinity DataIC50:  8nMAssay Description:Inhibition of human thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50129968(4-[7-(1,1-Dimethyl-2-oxo-2-piperidin-1-yl-ethyl)-4...)
Affinity DataIC50:  8nMAssay Description:Inhibition of human thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50129973(2-[3-(4-Carbamimidoyl-benzyl)-1-methyl-2-oxo-1,2-d...)
Affinity DataIC50:  10nMAssay Description:Inhibition of human thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50129979(4-{7-[1,1-Dimethyl-2-(3-methyl-piperidin-1-yl)-2-o...)
Affinity DataIC50:  12nMAssay Description:Inhibition of human thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50129974(4-{7-[1-(2-Hydroxymethyl-pyrrolidine-1-carbonyl)-c...)
Affinity DataIC50:  13nMAssay Description:Inhibition of human thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50129969(CHEMBL74263 | N-{1-[3-(4-Carbamimidoyl-benzyl)-1-m...)
Affinity DataIC50:  15nMAssay Description:Inhibition of human thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50129972(2-[3-(4-Carbamimidoyl-benzyl)-1-methyl-2-oxo-1,2-d...)
Affinity DataIC50:  16nMAssay Description:Inhibition of human thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50129970(1-[3-(4-Carbamimidoyl-benzyl)-1-methyl-2-oxo-1,2-d...)
Affinity DataIC50:  27nMAssay Description:Inhibition of human thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50129964(1-[2-(4-Carbamimidoyl-phenoxy)-4-methyl-quinolin-7...)
Affinity DataIC50:  30nMAssay Description:Inhibition of human thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50129975(4-[7-(1,1-Dimethyl-2-oxo-2-piperazin-1-yl-ethyl)-4...)
Affinity DataIC50:  68nMAssay Description:Inhibition of human thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50129976(4-{4-Methyl-3-oxo-7-[1-(pyrrolidine-1-carbonyl)-cy...)
Affinity DataIC50:  84nMAssay Description:Inhibition of coagulation factor XMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50129978(CHEMBL76068 | [(1-{1-[3-(4-Carbamimidoyl-benzyl)-1...)
Affinity DataIC50:  190nMAssay Description:Inhibition of human thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50129968(4-[7-(1,1-Dimethyl-2-oxo-2-piperidin-1-yl-ethyl)-4...)
Affinity DataIC50:  400nMAssay Description:Inhibition of coagulation factor XMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50129977(4-[7-(1,1-Dimethyl-2-oxo-2-pyrrolidin-1-yl-ethyl)-...)
Affinity DataIC50:  500nMAssay Description:Inhibition of coagulation factor XMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50129979(4-{7-[1,1-Dimethyl-2-(3-methyl-piperidin-1-yl)-2-o...)
Affinity DataIC50:  590nMAssay Description:Inhibition of coagulation factor XMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50129974(4-{7-[1-(2-Hydroxymethyl-pyrrolidine-1-carbonyl)-c...)
Affinity DataIC50:  1.40E+3nMAssay Description:Inhibition of coagulation factor XMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50129964(1-[2-(4-Carbamimidoyl-phenoxy)-4-methyl-quinolin-7...)
Affinity DataIC50:  1.50E+3nMAssay Description:Inhibition of coagulation factor XMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50129969(CHEMBL74263 | N-{1-[3-(4-Carbamimidoyl-benzyl)-1-m...)
Affinity DataIC50:  3.00E+3nMAssay Description:Inhibition of coagulation factor XMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50129971(1-[3-(4-Carbamimidoyl-benzyl)-1-methyl-2-oxo-1,2-d...)
Affinity DataIC50:  3.30E+3nMAssay Description:Inhibition of human thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasminogen(Homo sapiens (Human))
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50129964(1-[2-(4-Carbamimidoyl-phenoxy)-4-methyl-quinolin-7...)
Affinity DataIC50:  5.80E+3nMAssay Description:Inhibition of plasminMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50129972(2-[3-(4-Carbamimidoyl-benzyl)-1-methyl-2-oxo-1,2-d...)
Affinity DataIC50:  9.20E+3nMAssay Description:Inhibition of coagulation factor XMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50129973(2-[3-(4-Carbamimidoyl-benzyl)-1-methyl-2-oxo-1,2-d...)
Affinity DataIC50:  1.06E+4nMAssay Description:Inhibition of coagulation factor XMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50129957(2-[2-(4-Carbamimidoyl-phenoxy)-4-methyl-quinolin-7...)
Affinity DataIC50:  1.21E+4nMAssay Description:Inhibition of coagulation factor XMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasminogen(Homo sapiens (Human))
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50129957(2-[2-(4-Carbamimidoyl-phenoxy)-4-methyl-quinolin-7...)
Affinity DataIC50:  2.00E+4nMAssay Description:Inhibition of plasminMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50129975(4-[7-(1,1-Dimethyl-2-oxo-2-piperazin-1-yl-ethyl)-4...)
Affinity DataIC50:  3.10E+4nMAssay Description:Inhibition of coagulation factor XMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasminogen(Homo sapiens (Human))
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50129969(CHEMBL74263 | N-{1-[3-(4-Carbamimidoyl-benzyl)-1-m...)
Affinity DataIC50:  3.60E+4nMAssay Description:Inhibition of plasminMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50129970(1-[3-(4-Carbamimidoyl-benzyl)-1-methyl-2-oxo-1,2-d...)
Affinity DataIC50:  4.60E+4nMAssay Description:Inhibition of coagulation factor XMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasminogen(Homo sapiens (Human))
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50129977(4-[7-(1,1-Dimethyl-2-oxo-2-pyrrolidin-1-yl-ethyl)-...)
Affinity DataIC50:  5.30E+4nMAssay Description:Inhibition of plasminMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasminogen(Homo sapiens (Human))
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50129968(4-[7-(1,1-Dimethyl-2-oxo-2-piperidin-1-yl-ethyl)-4...)
Affinity DataIC50:  6.00E+4nMAssay Description:Inhibition of plasminMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasminogen(Homo sapiens (Human))
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50129976(4-{4-Methyl-3-oxo-7-[1-(pyrrolidine-1-carbonyl)-cy...)
Affinity DataIC50:  6.60E+4nMAssay Description:Inhibition of plasminMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasminogen(Homo sapiens (Human))
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50129978(CHEMBL76068 | [(1-{1-[3-(4-Carbamimidoyl-benzyl)-1...)
Affinity DataIC50:  6.80E+4nMAssay Description:Inhibition of plasminMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasminogen(Homo sapiens (Human))
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50129970(1-[3-(4-Carbamimidoyl-benzyl)-1-methyl-2-oxo-1,2-d...)
Affinity DataIC50:  6.90E+4nMAssay Description:Inhibition of plasminMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasminogen(Homo sapiens (Human))
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50129974(4-{7-[1-(2-Hydroxymethyl-pyrrolidine-1-carbonyl)-c...)
Affinity DataIC50:  7.20E+4nMAssay Description:Inhibition of plasminMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasminogen(Homo sapiens (Human))
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50129973(2-[3-(4-Carbamimidoyl-benzyl)-1-methyl-2-oxo-1,2-d...)
Affinity DataIC50:  7.50E+4nMAssay Description:Inhibition of plasminMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50129978(CHEMBL76068 | [(1-{1-[3-(4-Carbamimidoyl-benzyl)-1...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of coagulation factor XMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasminogen(Homo sapiens (Human))
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50129972(2-[3-(4-Carbamimidoyl-benzyl)-1-methyl-2-oxo-1,2-d...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of plasminMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50129971(1-[3-(4-Carbamimidoyl-benzyl)-1-methyl-2-oxo-1,2-d...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of coagulation factor XMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed